A miRNA signature predicts benefit from addition of hypoxia-modifying therapy to radiation treatment in invasive bladder cancer.

Autor: Khan MT; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie NHS Foundation Trust Hospital, Manchester, UK., Irlam-Jones JJ; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie NHS Foundation Trust Hospital, Manchester, UK., Pereira RR; Translational Oncogenomics, Cancer Research UK Manchester Institute, Oglesby Cancer Research Building, University of Manchester, Manchester, UK., Lane B; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie NHS Foundation Trust Hospital, Manchester, UK., Valentine HR; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie NHS Foundation Trust Hospital, Manchester, UK., Aragaki K; Greenberg Bladder Cancer Institute, Johns Hopkins University, Baltimore, MD, USA., Dyrskjøt L; Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., McConkey DJ; Greenberg Bladder Cancer Institute, Johns Hopkins University, Baltimore, MD, USA., Hoskin PJ; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie NHS Foundation Trust Hospital, Manchester, UK., Choudhury A; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie NHS Foundation Trust Hospital, Manchester, UK., West CML; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie NHS Foundation Trust Hospital, Manchester, UK. Catharine.West@manchester.ac.uk.

Publikováno v: British journal of cancer [Br J Cancer] 2021 Jul; Vol. 125 (1), pp. 85-93. Date of Electronic Publication: 2021 Apr 12.

Selection of endogenous control genes for normalising gene expression data derived from formalin-fixed paraffin-embedded tumour tissue.

Autor: Smith TAD; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Centre, Christie Hospital NHS Found Trust, Manchester, M20 4BX, UK. tim.smith@manchester.ac.uk., AbdelKarem OA; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Centre, Christie Hospital NHS Found Trust, Manchester, M20 4BX, UK.; Medical Research Institute, Alexandria University, 165 El-Horreya Avenue, El-Hadra, Alexandria, Egypt., Irlam-Jones JJ; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Centre, Christie Hospital NHS Found Trust, Manchester, M20 4BX, UK., Lane B; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Centre, Christie Hospital NHS Found Trust, Manchester, M20 4BX, UK., Valentine H; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Centre, Christie Hospital NHS Found Trust, Manchester, M20 4BX, UK., Bibby BAS; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Centre, Christie Hospital NHS Found Trust, Manchester, M20 4BX, UK., Denley H; Pathology Centre, Shrewsbury and Telford NHS Trust, Royal Shrewsbury Hospital, Shrewsbury, SY3 8XQ, UK., Choudhury A; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Centre, Christie Hospital NHS Found Trust, Manchester, M20 4BX, UK., West CML; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Centre, Christie Hospital NHS Found Trust, Manchester, M20 4BX, UK.

Publikováno v: Scientific reports [Sci Rep] 2020 Oct 14; Vol. 10 (1), pp. 17258. Date of Electronic Publication: 2020 Oct 14.

Targeting hypoxia in solid and haematological malignancies.

Autor: Harris, Bill¹ (AUTHOR), Saleem, Sana² (AUTHOR), Cook, Natalie^1,3 (AUTHOR), Searle, Emma^2,3 (AUTHOR) emma.searle9@nhs.net

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 11/2/2022, Vol. 41 Issue 1, p1-16. 16p.

Comparison of multiple gene expression platforms for measuring a bladder cancer hypoxia signature.

Autor: Smith, Tim A.D.¹ (AUTHOR) tim.smith@manchester.ac.uk, Lane, Brian¹ (AUTHOR), More, Elisabet¹ (AUTHOR), Valentine, Helen¹ (AUTHOR), Lunj, Sapna¹ (AUTHOR), Abdelkarem, Omneya A.² (AUTHOR), Irlam-Jones, J.¹ (AUTHOR), Shabbir, Rekaya¹ (AUTHOR), Vora, Shrushti¹ (AUTHOR), Denley, Helen³ (AUTHOR), Reeves, Kimberley J.¹ (AUTHOR), Hoskin, Peter J.^1,4 (AUTHOR), Choudhury, Ananya^1,4 (AUTHOR), West, Catharine M.L.¹ (AUTHOR)

Publikováno v: Molecular Medicine Reports. Aug2022, Vol. 26 Issue 2, pN.PAG-N.PAG. 1p.

Role and mechanisms of noncoding RNAs in the regulation of metabolic reprogramming in bladder cancer (Review).

Autor: Zhang, Bin, Yang, Liming, He, Yang, Han, Dali, Qi, Peng, Shang, Panfeng

Publikováno v: International Journal of Molecular Medicine; Sep2023, Vol. 52 Issue 3, pN.PAG-N.PAG, 1p