Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Irit Shefler"'
Publikováno v:
Cells, Vol 11, Iss 3, p 353 (2022)
Mast cells (MCs) function as a component of the tumor microenvironment (TME) and have both pro- and anti-tumorigenic roles depending on the tumor type and its developmental stage. Several reports indicate the involvement of MCs in angiogenesis in the
Externí odkaz:
https://doaj.org/article/025bbcca273a45988a8fc5f692e3b575
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9176 (2021)
Mast cells are major effector cells in eliciting allergic responses. They also play a significant role in establishing innate and adaptive immune responses, as well as in modulating tumor growth. Mast cells can be activated upon engagement of the hig
Externí odkaz:
https://doaj.org/article/e5e7a89de12647f49106d6532ae8eb1b
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 9, p 2145 (2019)
Allergic inflammation is accompanied by the coordinated expression of numerous genes and proteins that initiate, sustain, and propagate immune responses and tissue remodeling. MicroRNAs (miRNAs) are a large class of small regulatory molecules that ar
Externí odkaz:
https://doaj.org/article/be3d0ca7670b458680cd3083e2ebdba9
Publikováno v:
Journal of Allergy and Clinical Immunology.
Autor:
Lea Bentur, Suhair Hanna, Pazit Salamon, Irit Shefler, Yael Ben-David Gadot, Szilvia Baron, Tal Freund, Ronit Confino-Cohen, David Hagin, idit Lachover Roth, Tova Hershkovitz
Publikováno v:
Journal of Clinical Immunology. 40:977-986
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder caused by defects in the NADPH oxidase complex. Mutations in NCF2 encoding the cytosolic factor p67phox result in autosomal recessive CGD. We describe three patients with
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9176, p 9176 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Mast cells are major effector cells in eliciting allergic responses. They also play a significant role in establishing innate and adaptive immune responses, as well as in modulating tumor growth. Mast cells can be activated upon engagement of the hig
Publikováno v:
Cancer immunology, immunotherapy : CII. 69(3)
Activated mast cells are often found in the tumor microenvironment. They have both pro- and anti-tumorigenic roles, depending on the tumor type. Several lines of evidence suggest that the tumor microenvironment contains multiple soluble factors that
Autor:
Itay Moshkovits, D. Horwitz Klotzman, Y. A. Mekori, Irit Shefler, Alon Y. Hershko, Pazit Salamon, Ariel Munitz
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 47(11)
Background We have previously shown that mast cells (MCs) suppress chronic allergic dermatitis in mice. The underlying mechanism involves MC-derived IL-2, which supports regulatory T cell (Treg) response at the site of inflammation. However, it is no
Autor:
Irit Shefler, Osnat Jarchwsky Dolberg, Oshrat Attar-Schneider, Liat Drucker, Michael Lishner, Shelly Tartakover Matalon, Mahmoud Dabbah
Publikováno v:
Carcinogenesis. 38(7)
Multiple myeloma (MM) cells' interaction with the bone marrow (BM) microenvironment critically hinders disease therapy. Previously, we showed that MM co-culture with BM-mesenchymal stem cells (MSCs) caused co-modulation of translation initiation (TI)
Publikováno v:
International Archives of Allergy and Immunology. 161:174-180
Background:Vespa orientalis (VO) stings occasionally induce anaphylaxis. In the absence of commercial VO venom, allergists use commercial venoms for immunotherapy, despite having no indication regarding efficacy. We attempted to examine the effective