Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Irit Gil-Ad"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2711 (2022)
Some selective serotonin reuptake inhibitors (SSRIs), primarily sertraline, demonstrate anti-proliferative activity in malignant cell-lines and in xenografted mouse models of colorectal tumor. There is, however, a paucity of comparative studies on th
Externí odkaz:
https://doaj.org/article/744c03558ade4d7ea4573d9b3f8271c4
Autor:
Konstantin Bloch, Shay Henry Hornfeld, Shira Dar, Alexey Vanichkin, Irit Gil-Ad, Pnina Vardi, Abraham Weizman
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227879 (2020)
Accumulating evidence suggests that Alzheimer's disease is associated with brain insulin resistance, as are some other types of dementia. Intranasal insulin administration has been suggested as a potential approach to overcoming brain insulin resista
Externí odkaz:
https://doaj.org/article/6b21641591c6463ebcc010eae6f955db
Autor:
Shay Henry Hornfeld, Alexey Vanichkin, Irit Gil-Ad, Abraham Weizman, Konstantin Bloch, Pnina Vardi, Shira Dar
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227879 (2020)
PLoS ONE
PLoS ONE
Accumulating evidence suggests that Alzheimer's disease is associated with brain insulin resistance, as are some other types of dementia. Intranasal insulin administration has been suggested as a potential approach to overcoming brain insulin resista
Autor:
Abraham Weizman, Alexey Vanichkin, Pnina Vardi, Michal Taler, Shay Henry Hornfeld, Nickolay Koroukhov, Irit Gil-Ad, Konstantin Bloch
Publikováno v:
Journal of Alzheimer's Disease. 60:121-136
Background Animal models of dementia associated with metabolic abnormalities play an important role in understanding the bidirectional relationships between these pathologies. Rodent strains develop cognitive dysfunctions without alteration of periph
Autor:
Abraham Weizman, Ran Barzilay, Akira Sawa, Michal Taler, Shay Henry Hornfeld, Atsushi Kamiya, Daniel Offen, Hadar Segal-Gavish, Minae Niwa, Irit Gil-Ad, Yael Barhum, Inna Slutsky, Tali Ben-Zur, Neta Gazit
Publikováno v:
Human Molecular Genetics. 26:2462-2471
Cannabis abuse in adolescence is associated with increased risk of psychotic disorders. Δ-9-tetrahydrocannabinol (THC) is the primary psychoactive component of cannabis. Disrupted-In-Schizophrenia-1 (DISC1) protein is a driver for major mental illne
Publikováno v:
Behavioural Brain Research. 323:141-145
Background Schizophrenia patients who do not respond to clozapine treatment represent the most debilitating type of schizophrenia with unmet needs for novel interventions. To date there is no validated animal model for clozapine-refractory schizophre
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 11:3263-3272
There is increasing evidence supporting a link between cognitive dysfunctions and impaired brain insulin signalling. Insulin therapy has previously been tested as an approach to ameliorate brain insulin resistance and deficiency in patients with vari
Publikováno v:
Transplantation. 103(6)
Autor:
Irit Gil-Ad, Abraham Weizman, Liat Shbiro, Israel Vered, Michal Taler, Aron Weller, Rea Globus
Publikováno v:
Journal of Molecular Neuroscience. 58:66-73
Olanzapine-induced weight gain is associated with atherosclerosis, hypertension, dyslipidemia, and diabetes. We synthesized a novel antipsychotic drug (PGW5) possessing an olanzapine moiety linked to sarcosine, a glycine transporter 1 inhibitor. In t
Autor:
Konstantin Bloch, Irit Gil-Ad, Alexey Vanichkin, Dmitry Azarov, Michal Taler, Pnina Vardi, Abraham Weizman, Shay Henry Hornfeld, Shira Dar
Publikováno v:
Journal of Alzheimer's disease : JAD. 65(4)
Background Alzheimer's disease (AD) is often associated with brain insulin resistance and peripheral metabolic dysfunctions. Recently, we developed a model of sporadic AD associated with obesity-related peripheral metabolic abnormalities in Lewis rat