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Akademický článek

It’s Time for Entropic Clocks: The Roles of Random Chain Protein Sequences in Timing Ion Channel Processes Underlying Action Potential Properties

Autor: Esraa Nsasra, Irit Dahan, Jerry Eichler, Ofer Yifrach

Publikováno v: Entropy, Vol 25, Iss 9, p 1351 (2023)

In recent years, it has become clear that intrinsically disordered protein segments play diverse functional roles in many cellular processes, thus leading to a reassessment of the classical structure–function paradigm. One class of intrinsically di

Externí odkaz: https://doaj.org/article/4997122b34374199b5f7a4bc5f6e17f0

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Akademický článek

Distinct features of the Leishmania cap-binding protein LeishIF4E2 revealed by CRISPR-Cas9 mediated hemizygous deletion.

Autor: Nofar Baron, Nitin Tupperwar, Irit Dahan, Uzi Hadad, Geula Davidov, Raz Zarivach, Michal Shapira

Publikováno v: PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0008352 (2021)

Leishmania parasites cycle between sand-fly vectors and mammalian hosts adapting to alternating environments by stage-differentiation accompanied by changes in the proteome profiles. Translation regulation plays a central role in driving the differen

Externí odkaz: https://doaj.org/article/1aa5824e79004b0d8ab45cfc75bf2165

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Akademický článek

Characterization of an Atypical eIF4E Ortholog in Leishmania, LeishIF4E-6

Autor: Nitin Tupperwar, Rohit Shrivastava, Nofar Baron, Orli Korchev, Irit Dahan, Michal Shapira

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 23, p 12720 (2021)

Leishmania parasites are digenetic protists that shuffle between sand fly vectors and mammalian hosts, transforming from flagellated extracellular promastigotes that reside within the intestinal tract of female sand flies to the obligatory intracellu

Externí odkaz: https://doaj.org/article/422f12c63a5b4f478dc1bc26003610e0

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Characterization of an Atypical eIF4E Ortholog in Leishmania, LeishIF4E-6

Autor: Irit Dahan, Orli Korchev, Nitin Tupperwar, Rohit Shrivastava, Michal Shapira, Nofar Baron

Publikováno v: International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 12720
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12720, p 12720 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5f68f422840ebfc9af6cb49af2a3b1

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Distinct features of the Leishmania cap-binding protein LeishIF4E2 revealed by CRISPR-Cas9 mediated hemizygous deletion

Autor: Nitin Tupperwar, Geula Davidov, Uzi Hadad, Nofar Baron, Irit Dahan, Michal Shapira, Raz Zarivach

Publikováno v: PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 3, p e0008352 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df7f2fe5a3e3a8504db8cad714279ef
https://pubmed.ncbi.nlm.nih.gov/33760809

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Post transcriptional control of gene expression in Leishmania

Autor: Srinivas Garlapati, Edit Dahan, Victoria Yavesky, Alon Zilka, Michal Shapira, Irit Dahan

Publikováno v: Scopus-Elsevier

Leishmania parasites are ancient eukaryotes, characterized by unusual molecular mechanisms. We have used the gene encoding for Hsp83 as a model system for studying regulatory mechanisms that control developmental gene regulation. We previously showed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879e99c77960bd07c90f778ea992b47c
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035175444&partnerID=MN8TOARS

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