Výsledky vyhledávání - "Irismara Sousa Silva"

Akademický článek

Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation

Autor: Irismara Sousa Silva, Aline D. Almeida, Antônio C. M. Lima Filho, Weslley Fernandes-Braga, Ayslan Barra, Hortência M. C. Oliveira, Geovanni D. Cassali, Luciano S. A. Capettini, Gustavo B. Menezes, Jacqueline I. Alvarez-Leite, Maria F. Leite, André Klein

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)

Abstract Although it is well established that platelet-activated receptor (PAF) and protease-activated receptor 2 (PAR2) play a pivotal role in the pathophysiology of lung and airway inflammatory diseases, a role for a PAR2-PAFR cooperation in lung i

Externí odkaz: https://doaj.org/article/63d5d9ce84214c99b674363f35ad3477

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Akademický článek

Caryocar villosum attenuates inflammation by inhibiting CXCL1 activation and peripheral hyperalgesia through opioid pathway modulation

Autor: Gutemberg Lopes SOARES, Lívia Christine Ribeiro HILGENBERG, Giovana Reis BATISTA, Matheus Kleber de Jesus SOUZA, Renata Cristina Mendes FERREIRA, Irismara Sousa SILVA, Tallita Marques MACHADO, Carlos Cleomir de Souza PINHEIRO, Fernanda GUILHON-SIMPLICIO, Andre KLEIN, Andrea de Castro PEREZ, Emerson Silva LIMA, Clarice de Carvalho Veloso MOURA

Publikováno v: Acta Amazonica, Vol 52, Iss 3, Pp 245-253 (2022)

ABSTRACT The oil of Caryocar villosum is used in Amazonian folk medicine to treat pain and inflammatory conditions. So, we assessed the anti-inflammatory and antinociceptive properties of the ethanolic extract obtained from the fruit peels of this sp

Externí odkaz: https://doaj.org/article/81b14d7df48c4b70abcf952e0536a422

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LyeTx I-b Peptide Attenuates Tumor Burden and Metastasis in a Mouse 4T1 Breast Cancer Model

Autor: Mostafa A. L. Abdel-Salam, Irismara Sousa Silva, Bárbara Luíza Alves Pinto, Lilian Lacerda Bueno, Geovanni Dantas Cassali, Fabrício Marcus Silva Oliveira, Maria Elena de Lima, André Klein, Elaine M. Souza-Fagundes, Gabriela Rafaela Arantes Pêgas, Juliana Carvalho-Tavares

Publikováno v: Antibiotics, Vol 10, Iss 1136, p 1136 (2021)
Antibiotics
Volume 10
Issue 9

Cationic anticancer peptides have exhibited potent anti-proliferative and anti-inflammatory effects in neoplastic illness conditions. LyeTx I-b is a synthetic peptide derived from Lycosa erythrognatha spider venom that previously showed antibiotic ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6792416a1e2edb9d5f783fc04b410d
https://www.mdpi.com/2079-6382/10/9/1136

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A role for mast cells and mast cell tryptase in driving neutrophil recruitment in LPS-induced lung inflammation via protease-activated receptor 2 in mice

Autor: M. Fatima Leite, Geovanni Dantas Cassali, Aline Dias de Almeida, Luciana O. Andrade, Antônio Carlos Melo LimaFilho, Rodrigo M. Florentino, Ayslan Barra, Irismara Sousa Silva, André Klein, Weslley Fernandes-Braga

Publikováno v: Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 69(10)

This study aims to investigate the role of protease-activated receptor (PAR) 2 and mast cell (MC) tryptase in LPS-induced lung inflammation and neutrophil recruitment in the lungs of C57BL/6 mice. C57BL/6 mice were pretreated with the PAR2 antagonist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634d96e0fcc8822c13510d4f3d8608e5
https://pubmed.ncbi.nlm.nih.gov/32767096

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H2S is a key antisecretory molecule against cholera toxin-induced diarrhoea in mice: Evidence for non-involvement of the AC/cAMP/PKA pathway and AMPK

Autor: Jand Venes R. Medeiros, Francisca Beatriz M. Sousa, Thiago S.L. Araújo, Jefferson Soares de Oliveira, Luan Kelves Miranda de Souza, Simone de Araújo, Marcellus H.L.P. Souza, Lucas A.D. Nicolau, Dvison M. Pacífico, Fabiana de Moura Souza, Marcelo de Carvalho Filgueiras, Renan O. Silva, Nayara A. Sousa, Irismara Sousa Silva

Publikováno v: Nitric Oxide. 76:152-163

Hydrogen sulphide (H2S) is a gasotransmitter that participates in various physiological and pathophysiological processes within the gastrointestinal tract. We studied the effects and possible mechanism of action of H2S in secretory diarrhoea caused b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61c9fcf16e6e4e49788047f6995aef6e
https://doi.org/10.1016/j.niox.2017.09.007

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Correction to: A role for mast cells and mast cell tryptase in driving neutrophil recruitment in LPS-induced lung inflammation via protease-activated receptor 2 in mice

Autor: Aline Dias de Almeida, Irismara Sousa Silva, Weslley Fernandes-Braga, Antônio Carlos Melo LimaFilho, Rodrigo Machado Florentino, Ayslan Barra, Luciana de Oliveira Andrade, M. Fátima Leite, Geovanni Dantas Cassali, André Klein

Publikováno v: Inflammation Research. 69:1071-1071

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::711bca0948252cf1a590630ee12435d3
https://doi.org/10.1007/s00011-020-01386-2

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