Radiation response assessment of organoids derived from patients with pancreatic cancer

Autor: Iris W.J.M. van Goor, Leon Raymakers, Daan S.H. Andel, Lodewijk A.A. Brosens, Onno Kranenburg, Jeanette H.W. Leusen, Gert J. Meijer, I. Quintus Molenaar, Hjalmar C. van Santvoort, J.H. Wilfred de Vries, Andre J.M. Wopereis, Martijn P.W. Intven, Lois A. Daamen

Publikováno v: Clinical and Translational Radiation Oncology, Vol 48, Iss , Pp 100829- (2024)

Background: The effectiveness of radiotherapy for pancreatic cancer is debated. Patient-derived organoids (PDOs) already mimicked clinical radiation response in other cancer types, which could be valuable in pancreatic cancer as well. This study aime

Externí odkaz: https://doaj.org/article/d8a344c2c6f941d3a03e2dacb74c34f8

Alternative Randomized Trial Designs in Surgery: A Systematic Review

Autor: Simone Augustinus, Iris W.J.M. van Goor, Johannes Berkhof, Lois A. Daamen, Bas Groot Koerkamp, Tara M. Mackay, I.Q Molenaar, Hjalmar C. van Santvoort, Helena M. Verkooijen, Peter M. van de Ven, Marc G. Besselink

Publikováno v: Annals of Surgery, 276(5), 753-760. Lippincott Williams and Wilkins
Annals of surgery, 276(5), 753-760. Lippincott Williams and Wilkins
Augustinus, S, van Goor, I W J M, Berkhof, J, Daamen, L A, Groot Koerkamp, B, Mackay, T M, Molenaar, I Q, van Santvoort, H C, Verkooijen, H M, van de Ven, P M & Besselink, M G 2022, ' Alternative Randomized Trial Designs in Surgery : A Systematic Review ', Annals of Surgery, vol. 276, no. 5, pp. 753-760 . https://doi.org/10.1097/SLA.0000000000005620
Annals of Surgery, 276(5), 753-760. Lippincott Williams & Wilkins

INTRODUCTION: Randomized controlled trials (RCTs) yield the highest level of evidence but are notoriously difficult to perform in surgery. Surgical RCTs may be hampered by slow accrual, the surgical learning curve, and lack of financial support. Alte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21493a9710f77dca35bfdd82f39da2b
https://pubmed.ncbi.nlm.nih.gov/35866665