Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Iris Speigel"'
Publikováno v:
Frontiers in Systems Neuroscience, Vol 11 (2017)
Anesthetics produce unconsciousness by modulating ion channels that control neuronal excitability. Research has shown that specific GABAA receptor (GABAAR) subtypes in particular regions of the central nervous system contribute to different hyperpola
Externí odkaz:
https://doaj.org/article/865173b012964e4fa402be45ee20e689
Volatile anesthetics alter presynaptic function including effects on Ca2+ influx and neurotransmitter release. These actions are proposed to play important roles in their pleiotropic neurophysiological effects including unconsciousness and amnesia. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8369f790827911b0c5612a0a4038cf3a
https://doi.org/10.1101/2022.01.03.474845
https://doi.org/10.1101/2022.01.03.474845
Autor:
Iris Speigel, Courtney C. Elder, Edyta K. Bichler, William R. Tyor, Shavonne L Teng, Paul S. García, Vincent T. Ciavatta
Publikováno v:
Neurochemical Research. 42:3220-3232
Although antiretroviral (ARV) therapy has reduced the incidence of severe dementia associated with HIV infection, there has been a rise in milder neurocognitive complaints. Data from HIV patients taking ARVs have shown measurable neurocognitive impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cbbc21c84a145ba683ff98a4254986b
https://doi.org/10.1007/s11064-017-2358-x
https://doi.org/10.1007/s11064-017-2358-x
Publikováno v:
Anesthesia and analgesia. 129(1)
Background Clinical studies implicate the perioperative period in cognitive complications, and increasing experimental evidence shows that the anesthetic agents can affect neuronal processes that underpin learning and memory. Calcineurin, a Ca-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24d19fa3c95bddcef78d6764a464d45
https://pubmed.ncbi.nlm.nih.gov/31082969
https://pubmed.ncbi.nlm.nih.gov/31082969
Autor:
Glenda L. Keating, Iris Speigel, Andrew Jenkins, Matthias Kreuzer, Paul S. García, Seyed A. Safavynia, David B. Rye, Jonathan A. Fidler
Publikováno v:
Anesthesiology. 125:147-158
Background Transitions into conscious states are partially mediated by inactivation of sleep networks and activation of arousal networks. Pharmacologic hastening of emergence from general anesthesia has largely focused on activating subcortical monoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96185eca3ced01254b0814bcdc0a8b3f
https://doi.org/10.1097/aln.0000000000001134
https://doi.org/10.1097/aln.0000000000001134
Publikováno v:
Annals of the New York Academy of Sciences. 1279:103-113
Afferent feedback alters muscle activity during locomotion and must be tightly controlled. As primary afferent depolarization-induced presynaptic inhibition (PAD-PSI) regulates afferent signaling, we investigated hindlimb PAD-PSI during locomotion in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40e0b47c7b7c47820c6406a870b8b512
https://doi.org/10.1111/nyas.12055
https://doi.org/10.1111/nyas.12055
Autor:
Seyed A. Safavynia, Glenda Keating, Iris Speigel, Jonathan A. Fidler, Matthias Kreuzer, David B. Rye, Andrew Jenkins, Paul S. García
Publikováno v:
Anesthesiology. 126:352-353
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb09b9d6a2f4bbc6905628301ab206b
https://doi.org/10.1097/aln.0000000000001446
https://doi.org/10.1097/aln.0000000000001446
Autor:
Jianxiong Jiang, Yi Quan, Iris Speigel, Raymond Dingledine, Thota Ganesh, Min Qui, Nadia Lelutiu, Yuhong Du, Geidy Serrano, Asheebo Rojas
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(8)
With interest waning in the use of cyclooxygenase-2 (COX-2) inhibitors for inflammatory disease, prostaglandin receptors provide alternative targets for the treatment of COX-2–mediated pathological conditions in both the periphery and the central n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f5391579b73ae1b2babfffdcf30702
https://pubmed.ncbi.nlm.nih.gov/22323596
https://pubmed.ncbi.nlm.nih.gov/22323596
Autor:
Iris Speigel
Publikováno v:
Molecular Therapy. 20:S143-S144
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dfb03304efcec6654d29f5ec428181a
https://doi.org/10.1016/s1525-0016(16)36170-6
https://doi.org/10.1016/s1525-0016(16)36170-6