Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Iris Quentin"'
Publikováno v:
Biochemical Pharmacology. 67:919-926
6- O -Palmitoyl ascorbic acid (PAA) has recently been used as a substitute for ascorbic acid because of its greater potency as an antioxidant. In detailed concentration response studies distinct cytotoxic effects of PAA at concentrations exceeding 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f1908087fc1c1be775c1d7d47f87d7
https://doi.org/10.1016/j.bcp.2003.10.001
https://doi.org/10.1016/j.bcp.2003.10.001
Autor:
Hans Jürgen Steinfelder, Iris Quentin, Mohammed Shaheen, Sylvia Kaap, Dereje Tamiru, Kurt Eger
Publikováno v:
Biochemical Pharmacology. 65:603-610
In the present study, we outlined the part of the molecule mediating the prominent pro-apoptotic effect of the Michael adduct of ascorbic acid with p-chloro-nitrostyrene, a new synthetic phosphatase inhibitor. The nitrostyrene (NS) moiety was identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a029f74eac2edc1c0ffe12253a913e
https://doi.org/10.1016/s0006-2952(02)01618-0
https://doi.org/10.1016/s0006-2952(02)01618-0
Autor:
Rüdiger Opitz, Frithjof Tergau, John Marwitz, Hans Jürgen Steinfelder, Iris Quentin, Vera Ritz, J. Weichert, Caroline von Zezschwitz
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 356:8-16
Two structurally different inhibitors of ser/thr phosphatases 1 and 2A, okadaic acid and calyculin A, time- and concentration-dependently stimulated and inhibited cell-specific function (hormone gene expression) in pituitary GH3 cells. The negative e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff1bfa45bf86008d843f1e46504d8dc
https://doi.org/10.1007/pl00005032
https://doi.org/10.1007/pl00005032
Publikováno v:
Journal of pharmacological and toxicological methods. 43(1)
Apoptotic cell death with its characteristic coordinated cellular breakdown can be triggered by cytotoxic drugs. One prominent feature that differentiates apoptotic from necrotic cell death is the caspase-mediated activation of an endonuclease that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6a1b880ea4c71b3f2645d14fd61d2a
https://pubmed.ncbi.nlm.nih.gov/11091133
https://pubmed.ncbi.nlm.nih.gov/11091133
Autor:
Christina Ziemann, John Marwitz, Hans Jürgen Steinfelder, Iris Quentin, Karen I. Hirsch-Ernst, S. Sieder, Vera Ritz
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 360(2)
Okadaic acid as well as other, structurally different, inhibitors of serine/threonine phosphatases 1 and 2A induce apoptosis in pituitary GH3 cells. Incubation with stepwise raised concentrations of okadaic acid resulted in the isolation of cells tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8cb296b6d28e90d945cf67110d69cb5
https://pubmed.ncbi.nlm.nih.gov/10494879
https://pubmed.ncbi.nlm.nih.gov/10494879
Autor:
Vera Ritz, John Marwitz, Hans Jürgen Steinfelder, Iris Quentin, Eva Richter, Christina Ziemann
Publikováno v:
Biochemical pharmacology. 54(9)
Pituitary GH3 cells die by apoptosis when treated with okadaic acid, a specific inhibitor of ser/thr phosphatases. Incubations starting at concentrations of 5 and 12.5 nM followed by stepwise rises resulted in two populations (the S1 and S2 sublines)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba90760bb2f695aea5ea68124b2b095
https://pubmed.ncbi.nlm.nih.gov/9374416
https://pubmed.ncbi.nlm.nih.gov/9374416