Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Iris L Romero"'
Association of Metformin Use with Outcomes in Advanced Endometrial Cancer Treated with Chemotherapy.
Autor:
Obiageli Ezewuiro, Tatyana A Grushko, Masha Kocherginsky, Mohammed Habis, Jean A Hurteau, Kathryn A Mills, Jessica Hunn, Olufunmilayo I Olopade, Gini F Fleming, Iris L Romero
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147145 (2016)
There is increasing evidence that metformin, a commonly used treatment for diabetes, might have the potential to be repurposed as an economical and safe cancer therapeutic. The aim of this study was to determine whether stage III-IV or recurrent endo
Externí odkaz:
https://doaj.org/article/bd820adbee604921aa45a8094b5ac95a
Autor:
Mohammed Habis, Kristen Wroblewski, Michael Bradaric, Nadia Ismail, S Diane Yamada, Lacey Litchfield, Ernst Lengyel, Iris L Romero
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104521 (2014)
To determine whether statin use is associated with improved epithelial ovarian cancer (OvCa) survival.This is a single-institution retrospective cohort review of patients treated for OvCa between 1992 and 2013. Inclusion criteria were International F
Externí odkaz:
https://doaj.org/article/8509e4c11ab04b42b43df6c1fef8b08e
Autor:
Peter C. Hart, Hilary A. Kenny, Niklas Grassl, Karen M. Watters, Lacey M. Litchfield, Fabian Coscia, Ivana Blaženović, Lisa Ploetzky, Oliver Fiehn, Matthias Mann, Ernst Lengyel, Iris L. Romero
Publikováno v:
Cell Reports, Vol 29, Iss 12, Pp 4086-4098.e6 (2019)
Summary: The tumor microenvironment (TME) plays a pivotal role in cancer progression, and, in ovarian cancer (OvCa), the primary TME is the omentum. Here, we show that the diabetes drug metformin alters mesothelial cells in the omental microenvironme
Externí odkaz:
https://doaj.org/article/0997e8ecfa2743a797aa257846e3877d
Autor:
Iris L. Romero, Ernst Lengyel, Olufunmilayo I. Olopade, S. Diane Yamada, Yusuke Nakamura, Ryuji Hamamoto, Ricardo R. Lastra, Stephanie M. McGregor, Mark A. Eckert, Peter C. Hart, Tatsuyuki Chiyoda
Fig S3 shows BRCA1 knockdown in IOSE and FT does not increase HK1 expression or AMPK activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36a2dcc7867b47d80c428e229cfa99f
https://doi.org/10.1158/1940-6207.22532365.v1
https://doi.org/10.1158/1940-6207.22532365.v1
Autor:
Ernst Lengyel, Melissa L. Gilliam, Helen H. Kim, Thomas N. Krausz, Daniela M. Dinulescu, Woo Seok Lee, Keeley L. Mui, Sujatha Jagadeeswaran, Ilyssa O. Gordon, Iris L. Romero
Perspective on this Article from Effects of Oral Contraceptives or a Gonadotropin-Releasing Hormone Agonist on Ovarian Carcinogenesis in Genetically Engineered Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d0da22896e287f938bc6cad1e42415
https://doi.org/10.1158/1940-6207.22524984.v1
https://doi.org/10.1158/1940-6207.22524984.v1
Autor:
Iris L. Romero, Ernst Lengyel, Jason W. Locasale, Stephanie M. McGregor, Ricardo Lastra, Rachel Loth, Chun-Yi Chiang, Marion Curtis, Melanie Weigert, Xiaojing Liu, Tatsuyuki Chiyoda, Peter C. Hart
Silencing SPHK1 promotes resistance to metformin-induced cytotoxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82da795a0ecc8a117ca7b7b8e4094dac
https://doi.org/10.1158/1541-7786.22512996.v1
https://doi.org/10.1158/1541-7786.22512996.v1
Autor:
Iris L. Romero, Ernst Lengyel, Jason W. Locasale, Stephanie M. McGregor, Ricardo Lastra, Rachel Loth, Chun-Yi Chiang, Marion Curtis, Melanie Weigert, Xiaojing Liu, Tatsuyuki Chiyoda, Peter C. Hart
Analysis of SPHK1 expression in multiple OvCa cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e7c4e10662e4eb5edb4818c6f5b077
https://doi.org/10.1158/1541-7786.22513011.v1
https://doi.org/10.1158/1541-7786.22513011.v1
Autor:
Iris L. Romero, Ernst Lengyel, Jason W. Locasale, Stephanie M. McGregor, Ricardo Lastra, Rachel Loth, Chun-Yi Chiang, Marion Curtis, Melanie Weigert, Xiaojing Liu, Tatsuyuki Chiyoda, Peter C. Hart
SPHK1 expression does not alter other markers of metformin sensitivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6a180c435e6c5208c4403fdfc5d1bd
https://doi.org/10.1158/1541-7786.22512993
https://doi.org/10.1158/1541-7786.22512993
Autor:
Iris L. Romero, Ernst Lengyel, Jason W. Locasale, Stephanie M. McGregor, Ricardo Lastra, Rachel Loth, Chun-Yi Chiang, Marion Curtis, Melanie Weigert, Xiaojing Liu, Tatsuyuki Chiyoda, Peter C. Hart
Knockdown of SPHK1 in OvCa cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05366f48a9982d79bf6c76ff45407227
https://doi.org/10.1158/1541-7786.22512990.v1
https://doi.org/10.1158/1541-7786.22512990.v1
Autor:
Ernst Lengyel, Melissa L. Gilliam, Helen H. Kim, Thomas N. Krausz, Daniela M. Dinulescu, Woo Seok Lee, Keeley L. Mui, Sujatha Jagadeeswaran, Ilyssa O. Gordon, Iris L. Romero
Supplementary Figure 1 from Effects of Oral Contraceptives or a Gonadotropin-Releasing Hormone Agonist on Ovarian Carcinogenesis in Genetically Engineered Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c5fd2ac4e1a8b6f3ec1d0fe2358fa0
https://doi.org/10.1158/1940-6207.22524981.v1
https://doi.org/10.1158/1940-6207.22524981.v1