Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Iris Kemler"'
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Chimeric antigen receptor T (CAR-T) cell therapy is a transformative approach to cancer eradication. CAR-T is expensive partly due to the restricted use of each CAR construct for specific tumors. Thus, a CAR construct with broad antitumor ac
Externí odkaz:
https://doaj.org/article/9696af58a68d4e7b92885885e2c3598d
Publikováno v:
Molecular Therapy: Oncolytics, Vol 12, Iss , Pp 68-78 (2019)
Recombinant measles viruses (MVs) have oncolytic activity against a variety of human cancers. However, their kinetics of spread within tumors has been unexplored. We established an intravital imaging system using the dorsal skin fold chamber, which a
Externí odkaz:
https://doaj.org/article/51be7ba9637f4df884bd4458f5417e19
Autor:
David R Berg, Chetan P Offord, Iris Kemler, Matthew K Ennis, Lawrence Chang, George Paulik, Zeljko Bajzer, Claudia Neuhauser, David Dingli
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 3, p e1006773 (2019)
Tumor therapy with replication competent viruses is an exciting approach to cancer eradication where viruses are engineered to specifically infect, replicate, spread and kill tumor cells. The outcome of tumor virotherapy is complex due to the variabl
Externí odkaz:
https://doaj.org/article/7859ac3f594a44ba9e5451fe1bff53ea
Publikováno v:
Molecular Therapy Oncolytics
Molecular Therapy: Oncolytics, Vol 12, Iss, Pp 68-78 (2019)
Molecular Therapy: Oncolytics, Vol 12, Iss, Pp 68-78 (2019)
Recombinant measles viruses (MVs) have oncolytic activity against a variety of human cancers. However, their kinetics of spread within tumors has been unexplored. We established an intravital imaging system using the dorsal skin fold chamber, which a
Publikováno v:
Blood Cancer Journal
Blood Cancer Journal, Vol 11, Iss 1, Pp 1-10 (2021)
Blood Cancer Journal, Vol 11, Iss 1, Pp 1-10 (2021)
Chimeric antigen receptor T (CAR-T) cell therapy is a transformative approach to cancer eradication. CAR-T is expensive partly due to the restricted use of each CAR construct for specific tumors. Thus, a CAR construct with broad antitumor activity ca
Autor:
Iris Kemler, David Dingli, Chetan P. Offord, George F. Paulik, Claudia Neuhauser, Zeljko Bajzer, David R. Berg, Matthew K. Ennis, Lawrence Chang
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 15, Iss 3, p e1006773 (2019)
PLoS Computational Biology, Vol 15, Iss 3, p e1006773 (2019)
Tumor therapy with replication competent viruses is an exciting approach to cancer eradication where viruses are engineered to specifically infect, replicate, spread and kill tumor cells. The outcome of tumor virotherapy is complex due to the variabl
Publikováno v:
Blood. 136:24-24
Chimeric antigen receptor T (CAR-T) cell therapy is a transformative approach to cancer eradication. CAR-T is expensive in part due to the restricted use of each CAR construct for a specific set of tumors such as B cell lymphoma targeted with CD19 an
Autor:
David Dingli, Chetan P. Offord, Mi Yeon Jung, Claudia Neuhauser, Matthew K. Ennis, Iris Kemler
The use of replication-competent viruses as oncolytic agents is rapidly expanding, with several oncolytic viruses approved for cancer therapy. As responses to therapy are highly variable, understanding the dynamics of therapy is critical for optimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d57389c823d919b28c9306cf3b6870
https://europepmc.org/articles/PMC6191353/
https://europepmc.org/articles/PMC6191353/
Publikováno v:
Scopus-Elsevier