Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Iris K. Pang"'
Autor:
Le Li, Alden King-Yung Leung, Tsz-Piu Kwok, Yvonne Y. Y. Lai, Iris K. Pang, Grace Tin-Yun Chung, Angel C. Y. Mak, Annie Poon, Catherine Chu, Menglu Li, Jacob J. K. Wu, Ernest T. Lam, Han Cao, Chin Lin, Justin Sibert, Siu-Ming Yiu, Ming Xiao, Kwok-Wai Lo, Pui-Yan Kwok, Ting-Fung Chan, Kevin Y. Yip
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-19 (2017)
Abstract We present a new method, OMSV, for accurately and comprehensively identifying structural variations (SVs) from optical maps. OMSV detects both homozygous and heterozygous SVs, SVs of various types and sizes, and SVs with or without creating
Externí odkaz:
https://doaj.org/article/fd1335bc468d46e4a3782b73f0fe7dac
Autor:
Edward T Schmid, Iris K Pang, Eugenio A Carrera Silva, Lidia Bosurgi, Jonathan J Miner, Michael S Diamond, Akiko Iwasaki, Carla V Rothlin
Publikováno v:
eLife, Vol 5 (2016)
The receptor tyrosine kinase (RTK) AXL is induced in response to type I interferons (IFNs) and limits their production through a negative feedback loop. Enhanced production of type I IFNs in Axl-/- dendritic cells (DCs) in vitro have led to speculati
Externí odkaz:
https://doaj.org/article/26ed936461cc4d648ecb813982f9941e
Autor:
Mark Trentalange, Huiping Dong, Akiko Iwasaki, Kimberly Martinod, Michal Caspi Tal, Albert C. Shaw, Ryan D. Molony, Richard A. Flavell, Angel G. Solis, Peter Staeheli, Robert J. Homer, Denisa D. Wagner, Ruth R. Montgomery, Piotr Bielecki, Subhasis Mohanty, Iris K. Pang, Padmini S. Pillai
Publikováno v:
Science. 352:463-466
Flu immunity shows its age As we age, our immune systems change; in many ways not for the better. For instance, the elderly account for 90% of influenza deaths annually. Pillai et al. now report that influenza-infected human monocytes, a type of immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856587a398437861ba873b320e970257
https://doi.org/10.1126/science.aaf3926
https://doi.org/10.1126/science.aaf3926
Autor:
Iris K. Pang, Alden King-Yung Leung, Tsz-Piu Kwok, Ming Xiao, Le Li, Pui-Yan Kwok, Siu-Ming Yiu, Angel C.Y. Mak, Grace Tin Yun Chung, Han Cao, Yvonne Y. Y. Lai, Menglu Li, Kwok Wai Lo, Chin Lin, Ernest T. Lam, Kevin Y. Yip, Justin Sibert, Catherine Chu, Ting-Fung Chan, Jacob J. K. Wu, Annie Poon
Publikováno v:
Genome biology, vol 18, iss 1
Genome Biology
Genome Biology, Vol 18, Iss 1, Pp 1-19 (2017)
Genome Biology
Genome Biology, Vol 18, Iss 1, Pp 1-19 (2017)
Human genomes contain structural variations (SVs) that are associated with various phenotypic variations and diseases. SV detection by sequencing is incomplete due to limited read length. Nanochannel-based optical mapping (OM) allows direct observati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324fbfab90f82ddcf18cdb6f905d8826
https://doi.org/10.1186/s13059-017-1356-2
https://doi.org/10.1186/s13059-017-1356-2
Autor:
Wei Jiang, Iris K. Pang, Weichuan Yu, Kevin Y. Yip, Landon L Chan, Nelson L.S. Tang, Danny Kit-Sang Yip
Publikováno v:
Bioinformatics (Oxford, England). 34(10)
Motivation Individual genetic variants explain only a small fraction of heritability in some diseases. Some variants have weak marginal effects on disease risk, but their joint effects are significantly stronger when occurring together. Most studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d92eb9011e5b8a281b62fc609f3dbe4
https://pubmed.ncbi.nlm.nih.gov/29329369
https://pubmed.ncbi.nlm.nih.gov/29329369
Publikováno v:
Nature immunology
Immune responses to vaccines require direct recognition of pathogen-associated molecular patterns (PAMPs) through pattern-recognition receptors (PRRs) on dendritic cells (DCs). Unlike vaccination, infection by a live pathogen often impairs DC functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905ca572a5e796176596902d8ef826d9
https://doi.org/10.1038/ni.2514
https://doi.org/10.1038/ni.2514
Autor:
Eugenio Antonio Carrera Silva, Iris K. Pang, Edward T. Schmid, Michael S. Diamond, Akiko Iwasaki, Carla V. Rothlin, Jonathan J. Miner, Lidia Bosurgi
Publikováno v:
eLife, Vol 5 (2016)
eLife
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
eLife
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The receptor tyrosine kinase (RTK) AXL is induced in response to type I interferons (IFNs) and limits their production through a negative feedback loop. Enhanced production of type I IFNs in Axl-/-dendritic cells (DCs) in vitro have led to speculatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb2690437c91e8e924b2ca569448f9c
https://elifesciences.org/articles/12414
https://elifesciences.org/articles/12414
Autor:
Akiko Iwasaki, Iris K. Pang, Carla V. Rothlin, Edward T. Schmid, Eugenio Antonio Carrera Silva, Lidia Bosurgi, Michael S. Diamond, Jonathan J. Miner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b748cb497767cd1c4a7a4d4583f13747
https://doi.org/10.7554/elife.12414.023
https://doi.org/10.7554/elife.12414.023
Autor:
Akiko Iwasaki, Iris K. Pang
Publikováno v:
Immunological Reviews. 245:209-226
Human skin and mucosal surfaces are in constant contact with resident and invasive microbes. Recognition of microbial products by receptors of the innate immune system triggers rapid innate defense and transduces signals necessary for initiating and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea9b1434313d8c1deb3798e02adc249d
https://doi.org/10.1111/j.1600-065x.2011.01073.x
https://doi.org/10.1111/j.1600-065x.2011.01073.x
Autor:
Yosuke Kumamoto, David R. Peaper, John Hsi En Ho, Takeshi Ichinohe, Akiko Iwasaki, Iris K. Pang, Thomas S. Murray
Publikováno v:
Proceedings of the National Academy of Sciences. 108:5354-5359
Although commensal bacteria are crucial in maintaining immune homeostasis of the intestine, the role of commensal bacteria in immune responses at other mucosal surfaces remains less clear. Here, we show that commensal microbiota composition criticall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35672136c235b40fcc2178f1427f0b7
https://doi.org/10.1073/pnas.1019378108
https://doi.org/10.1073/pnas.1019378108