Zobrazeno 1 - 10 of 65 pro vyhledávání: '"Iris K Gratz"'
1
Akademický článek
Th17-associated cytokines IL-17 and IL-23 in inflamed skin of Darier disease patients as potential therapeutic targets
Autor: Monika Ettinger, Teresa Burner, Anshu Sharma, Yun-Tsan Chang, Angelika Lackner, Pacôme Prompsy, Isabella M. Deli, Judith Traxler, Gerald Wahl, Sabine Altrichter, Rupert Langer, Yi-Chien Tsai, Suraj R. Varkhande, Leonie C. Schoeftner, Christoph Iselin, Iris K. Gratz, Susanne Kimeswenger, Emmanuella Guenova, Wolfram Hoetzenecker
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Darier disease (DD) is a rare, inherited multi-organ disorder associated with mutations in the ATP2A2 gene. DD patients often have skin involvement characterized by malodorous, inflamed skin and recurrent, severe infections. Therapeutic opti
Externí odkaz: https://doaj.org/article/8eec8722afcf4e4cb83878c6585c3720
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2
Akademický článek
H. pylori modulates DC functions via T4SS/TNFα/p38-dependent SOCS3 expression
Autor: Muamera Sarajlic, Theresa Neuper, Julia Vetter, Susanne Schaller, Maria M. Klicznik, Iris K. Gratz, Silja Wessler, Gernot Posselt, Jutta Horejs-Hoeck
Publikováno v: Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background Helicobacter pylori (H. pylori) is a gram-negative bacterium that chronically infects approximately 50% of the world’s human population. While in most cases the infection remains asymptomatic, 10% of infected individuals develop
Externí odkaz: https://doaj.org/article/4b1927efd9f143bab78e236d0d58c86c
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3
Akademický článek
Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity
Autor: Sandra Grund‐Gröschke, Daniela Ortner, Antal B. Szenes‐Nagy, Nadja Zaborsky, Richard Weiss, Daniel Neureiter, Martin Wipplinger, Angela Risch, Peter Hammerl, Richard Greil, Maria Sibilia, Iris K. Gratz, Patrizia Stoitzner, Fritz Aberger
Publikováno v: Molecular Oncology, Vol 14, Iss 9, Pp 1930-1946 (2020)
Genetic activation of hedgehog/glioma‐associated oncogene homolog (HH/GLI) signaling causes basal cell carcinoma (BCC), a very frequent nonmelanoma skin cancer. Small molecule targeting of the essential HH effector Smoothened (SMO) has proven an ef
Externí odkaz: https://doaj.org/article/010906a9f19b493eb18dbcddbbcc7354
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9
Targeting of Th17-related cytokines in patients with Darier Disease
Autor: Monika Ettinger, Teresa Burner, Isabella Pospischil, Judith Traxler, Gerald Wahl, Sabine Altrichter, Angelika Lackner, Iris K. Gratz, Susanne Kimeswenger, Emmanuella Guenova, Wolfram Hoetzenecker
Darier disease (DD) is a rare, inherited multi-organ disorder associated with mutations in the ATP2A2 gene. In DD patients, the skin is frequently affected, characterized by malodorous, inflamed skin and recurrent, severe infections. Therapeutic opti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36f7212c6939745544605c36a8c880f6
https://doi.org/10.1101/2023.01.12.22283857
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