Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Iris J. Broce"'
Autor:
Iris J. Broce, Daniel W. Sirkis, Ryan M. Nillo, Luke W. Bonham, Suzee E. Lee, Bruce L. Miller, Patricia A. Castruita, Virginia E. Sturm, Leo S. Sugrue, Rahul S. Desikan, Jennifer S. Yokoyama
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionA hexanucleotide repeat expansion (HRE) intronic to chromosome 9 open reading frame 72 (C9orf72) is recognized as the most common genetic cause of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and ALS-FTD. Identifyin
Externí odkaz:
https://doaj.org/article/b13a9c462df547a2b3c345568ced924f
Autor:
Iris J. Broce, Eduardo Caverzasi, Simone Sacco, Ryan Michael Nillo, Matteo Paoletti, Rahul S. Desikan, Michael Geschwind, Leo P. Sugrue
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 4, Pp 536-552 (2023)
Abstract Objective We explored the relationship between regional PRNP expression from healthy brain tissue and patterns of increased and decreased diffusion and regional brain atrophy in patients with sporadic Creutzfeldt‐Jakob disease (sCJD). Meth
Externí odkaz:
https://doaj.org/article/f481a90225ed48069de2f37731034c6f
Autor:
William G. Mantyh, J. Nicholas Cochran, Jared W. Taylor, Iris J. Broce, Ethan G. Geier, Luke W. Bonham, Ashlyn G. Anderson, Daniel W. Sirkis, Renaud La Joie, Leonardo Iaccarino, Kiran Chaudhary, Lauren Edwards, Amelia Strom, Harli Grant, Isabel E. Allen, Zachary A. Miller, Marilu L. Gorno‐Tempini, Joel H. Kramer, Bruce L. Miller, Rahul S. Desikan, Gil D. Rabinovici, Jennifer S. Yokoyama
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 4, Pp n/a-n/a (2023)
Abstract Early‐onset Alzheimer's disease (AD) is highly heritable, yet only 10% of cases are associated with known pathogenic mutations. For early‐onset AD patients without an identified autosomal dominant cause, we hypothesized that their early
Externí odkaz:
https://doaj.org/article/4906107fb48d48b98f50a0cb0d77e800
Autor:
Ryan M. Nillo, Iris J. Broce, Besim Uzgil, Nilika S. Singhal, Christine M. Glastonbury, Christopher P. Hess, James A. Barkovich, Rahul S. Desikan, Leo P. Sugrue
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background Anti-NMDA receptor encephalitis is an immune-mediated disorder characterized by antibodies against the GluN1 subunit of the NMDA receptor that is increasingly recognized as a treatable cause of childhood epileptic encephalopathy.
Externí odkaz:
https://doaj.org/article/b9cbc4ff762349d6927a4f2ad7bb1b4a
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating and intertwined neurodegenerative diseases. Historically, ALS and FTD were considered distinct disorders given differences in presenting clinical symptoms, dise
Externí odkaz:
https://doaj.org/article/be084ca48992498b9e5640cd028cf508
Autor:
Iris J. Broce, Eduardo Caverzasi, Simone Sacco, Ryan Michael Nillo, Matteo Paoletti, Rahul S. Desikan, Michael Geschwind, Leo P. Sugrue
Publikováno v:
Annals of Clinical and Translational Neurology. 10:536-552
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fb6e0fb5d0c65d334946d675723f63d
https://doi.org/10.1002/acn3.51739
https://doi.org/10.1002/acn3.51739
Autor:
Iris J. Broce, Leo P. Sugrue, Nilika S. Singhal, Rahul S. Desikan, Besim Uzgil, Ryan M. Nillo, James Barkovich, Christine M. Glastonbury, Christopher P. Hess
Publikováno v:
BMC Neurology
BMC neurology, vol 21, iss 1
BMC Neurology, Vol 21, Iss 1, Pp 1-6 (2021)
BMC neurology, vol 21, iss 1
BMC Neurology, Vol 21, Iss 1, Pp 1-6 (2021)
Background Anti-NMDA receptor encephalitis is an immune-mediated disorder characterized by antibodies against the GluN1 subunit of the NMDA receptor that is increasingly recognized as a treatable cause of childhood epileptic encephalopathy. In adults
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c55cce8b9ed0560432e25d0687e2c8
http://europepmc.org/articles/PMC8554978
http://europepmc.org/articles/PMC8554978
Autor:
Margaret A. Pericak-Vance, Linda K. McEvoy, Howard Feldman, Bradley T. Hyman, Richard Mayeux, Natalie Wen, Iris E. Jansen, Ole A. Andreassen, Chun Chieh Fan, Gerard D. Schellenberg, Bruce L. Miller, Aree Witoelar, Jeanne E. Savage, David A. Bennett, Christopher P. Hess, James B. Brewer, Iris J. Broce, Anders M. Dale, Leo P. Sugrue, Fanny M. Elahi, Danielle Posthuma, Chin Hong Tan, Reisa A. Sperling, Celeste M. Karch, Kristine Yaffe, Elizabeth C. Mormino, Jonathan L. Haines, M. Maria Glymour, Rahul S. Desikan, Gil D. Rabinovici, Christine M. Glastonbury, Lindsay A. Farrer, William P. Dillon, Jennifer S. Yokoyama
Publikováno v:
Broce, I J, Tan, C H, Fan, C C, Jansen, I, Savage, J E, Witoelar, A, Wen, N, Hess, C P, Dillon, W P, Glastonbury, C M, Glymour, M, Yokoyama, J S, Elahi, F M, Rabinovici, G D, Miller, B L, Mormino, E C, Sperling, R A, Bennett, D A, McEvoy, L K, Brewer, J B, Feldman, H H, Hyman, B T, Pericak-Vance, M, Haines, J L, Farrer, L A, Mayeux, R, Schellenberg, G D, Yaffe, K, Sugrue, L P, Dale, A M, Posthuma, D, Andreassen, O A, Karch, C M & Desikan, R S 2019, ' Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease ', Acta Neuropathologica, vol. 137, no. 2, pp. 209-226 . https://doi.org/10.1007/s00401-018-1928-6
Acta Neuropathologica, 137(2), 209-226. Springer Verlag
Broce, I J, Tan, C H, Fan, C C, Jansen, I, Savage, J E, Witoelar, A, Wen, N, Hess, C P, Dillon, W P, Glastonbury, C M, Glymour, M, Yokoyama, J S, Elahi, F M, Rabinovici, G D, Miller, B L, Mormino, E C, Sperling, R A, Bennett, D A, McEvoy, L K, Brewer, J B, Feldman, H H, Hyman, B T, Pericak-Vance, M, Haines, J L, Farrer, L A, Mayeux, R, Schellenberg, G D, Yaffe, K, Sugrue, L P, Dale, A M, Posthuma, D, Andreassen, O A, Karch, C M & Desikan, R S 2019, ' Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease ', Acta Neuropathologica, vol. 137, pp. 209-226 . https://doi.org/10.1007/s00401-018-1928-6
Acta Neuropathologica, 137, 209-226. Springer Verlag
Broce, IJ; Tan, CH; Fan, CC; Jansen, I; Savage, JE; Witoelar, A; et al.(2018). Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease. Acta Neuropathologica. doi: 10.1007/s00401-018-1928-6. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7137q6g1
Acta neuropathologica, vol 137, iss 2
Acta Neuropathologica, 137(2), 209-226. Springer Verlag
Broce, I J, Tan, C H, Fan, C C, Jansen, I, Savage, J E, Witoelar, A, Wen, N, Hess, C P, Dillon, W P, Glastonbury, C M, Glymour, M, Yokoyama, J S, Elahi, F M, Rabinovici, G D, Miller, B L, Mormino, E C, Sperling, R A, Bennett, D A, McEvoy, L K, Brewer, J B, Feldman, H H, Hyman, B T, Pericak-Vance, M, Haines, J L, Farrer, L A, Mayeux, R, Schellenberg, G D, Yaffe, K, Sugrue, L P, Dale, A M, Posthuma, D, Andreassen, O A, Karch, C M & Desikan, R S 2019, ' Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease ', Acta Neuropathologica, vol. 137, pp. 209-226 . https://doi.org/10.1007/s00401-018-1928-6
Acta Neuropathologica, 137, 209-226. Springer Verlag
Broce, IJ; Tan, CH; Fan, CC; Jansen, I; Savage, JE; Witoelar, A; et al.(2018). Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease. Acta Neuropathologica. doi: 10.1007/s00401-018-1928-6. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7137q6g1
Acta neuropathologica, vol 137, iss 2
© 2018, Springer-Verlag GmbH Germany, part of Springer Nature. Cardiovascular (CV)- and lifestyle-associated risk factors (RFs) are increasingly recognized as important for Alzheimer’s disease (AD) pathogenesis. Beyond the ε4 allele of apolipopro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7937967368dc1ec426c2d72d56a1df9e
https://research.vu.nl/en/publications/690d3837-845d-4d28-880e-8e73781e910c
https://research.vu.nl/en/publications/690d3837-845d-4d28-880e-8e73781e910c
Autor:
Martha L. Daviglus, Myriam Fornage, Richard B. Lipton, Melissa Lamar, Sylvia Wassertheil-Smoller, Nuzulul Kurniansyah, Charles DeCarli, Einat Granot-Hershkovitz, Tamar Sofer, Matthew Goodman, Iris J. Broce, Jianwen Cai, Hector M. González, Wassim Tarraf
IntroductionPolygenic Risk Score (PRS) are powerful summaries of genetic risk alleles that can potentially be used to predict disease outcomes and guide treatment decisions. Hispanics/Latinos suffer from higher rates of Alzheimer’s Disease (AD) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81bce4691d75c16016098da3c003cbe8
https://doi.org/10.1101/2021.01.08.21249413
https://doi.org/10.1101/2021.01.08.21249413
Autor:
Rahul S. Desikan, Jennifer S. Yokoyama, Nicholas J. Schmansky, Daniel Cuneo, William P. Dillon, Chun Chieh Fan, Matthew J. Barkovich, Ryan M. Nillo, Yi Li, Bruce L. Miller, Celeste M. Karch, Chin Hong Tan, Christopher P. Hess, Nicholas T. Olney, Ole A. Andreassen, Luke W. Bonham, Iris J. Broce, Terry L. Jernigan, Christine M. Glastonbury, A. James Barkovich, Leo P. Sugrue, Anders M. Dale, Aimee W. Kao, Orit A. Glenn, Bruce Fischl
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific reports, vol 8, iss 1
Scientific Reports
Li, Y; Barkovich, MJ; Karch, CM; Nillo, RM; Fan, CC; Broce, IJ; et al.(2018). Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex. Scientific Reports, 8(1). doi: 10.1038/s41598-018-31075-4. UCSF: Retrieved from: http://www.escholarship.org/uc/item/3m61c5mt
Li, Yi; Barkovich, Matthew J; Karch, Celeste M; Nillo, Ryan M; Fan, Chun-Chieh; Broce, Iris J; et al.(2018). Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex. Scientific Reports, 8(1). doi: 10.1038/s41598-018-31075-4. UCSF: UCSF Library. Retrieved from: http://www.escholarship.org/uc/item/4zk6w74d
Scientific reports, vol 8, iss 1
Scientific Reports
Li, Y; Barkovich, MJ; Karch, CM; Nillo, RM; Fan, CC; Broce, IJ; et al.(2018). Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex. Scientific Reports, 8(1). doi: 10.1038/s41598-018-31075-4. UCSF: Retrieved from: http://www.escholarship.org/uc/item/3m61c5mt
Li, Yi; Barkovich, Matthew J; Karch, Celeste M; Nillo, Ryan M; Fan, Chun-Chieh; Broce, Iris J; et al.(2018). Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex. Scientific Reports, 8(1). doi: 10.1038/s41598-018-31075-4. UCSF: UCSF Library. Retrieved from: http://www.escholarship.org/uc/item/4zk6w74d
Tuberous sclerosis complex (TSC), a heritable neurodevelopmental disorder, is caused by mutations in the TSC1 or TSC2 genes. To date, there has been little work to elucidate regional TSC1 and TSC2 gene expression within the human brain, how it change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c58087a886c9e4b80987e421701bd79
http://link.springer.com/article/10.1038/s41598-018-31075-4
http://link.springer.com/article/10.1038/s41598-018-31075-4