Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Iris Halfpenny"'
Autor:
Fabiana Ramos Vasques, Phil Quirke, Fiona S. Togneri, Katherine E. Keating, Iris Halfpenny, Karen G. Spink, M Taylor, Debra Hau, Dominic J. McMullan, Fiona Brew, Paul Wallace Medlow, E Tinkler-Hundal, K Southward, Joseph M. Foster, Michael J. Griffiths, Keith McGreeghan-Crosby, Assa Oumie
Publikováno v:
BMC Medical Genomics
Background Adoption of new technology in both basic research and clinical settings requires rigorous validation of analytical performance. The OncoScan® FFPE Assay is a multiplexing tool that offers genome-wide copy number and loss of heterozygosity
Autor:
Derek Middleton, Iris Halfpenny, Carlos Vilches, R Solís, E Estefanía, Fionnuala Williams, Natalia Gómez-Lozano
Publikováno v:
European Journal of Immunology. 35:16-24
Killer-cell Ig-like receptors (KIR) are structurally and functionally diverse, and enable human NK cells to survey the expression of individual HLA class I molecules, often altered in infections and tumors. Multiple events of non-reciprocal recombina
Autor:
Iris Halfpenny, Robert Gallavan, Mark W. Farmen, Keith McGreeghan-Crosby, Fabio P. Nunes, Gera Jellema, Steven M. Bray, Paul Medlow, Candice Horn, John N. Calley, Isabella H. Wulur
Publikováno v:
Cancer Research. 75:LB-048
Introduction: Somatic mutations are routinely identified using NGS cancer panels but these panels lack genome-wide coverage for copy number (CN) and LOH analysis. To investigate mutation, CN, and LOH in late-stage breast cancer we tested >50 samples
Autor:
A. Meenagh, Iris Halfpenny, Fionnula Williams, Jyrki Sivula, Derek Middleton, Eva Tuomilehto-Wolf
Publikováno v:
Human immunology. 67(12)
The frequency of killer immunoglobulinlike receptors (KIR) genes was examined in type 1 diabetes mellitus patients and controls from Finland. The KIR gene 2DS5 was significantly decreased in patients versus controls, but this was no longer significan
Autor:
Steve Deharo, Andrena McCavigan, Michael Churchman, Alistair R.W. Williams, James Paul, Charlie Gourley, Eamonn J. O'Brien, Laura Hill, Patrick G. Johnston, W. Glenn McCluggage, Richard D. Kennedy, Mahesh K. B. Parmar, Iris Halfpenny, Olaide Raji, D. Paul Harkin, Richard Kaplan, Caroline O. Michie, Katherine E. Keating, Timothy J. Perren, Timothy Davison
Publikováno v:
Journal of Clinical Oncology. 32:5502-5502
5502 Background: HGSOC is a histopathological diagnosis and may represent multiple diseases at a molecular level. We investigated whether distinct molecular subgroups may influence treatment choice...
Autor:
Richard D. Kennedy, Jude M. Mulligan, Thomas F. DeLaney, Katherine E. Keating, Paul B. Mullan, Vitali Proutski, Noralane M. Lindor, F. A. McDyer, Iris Halfpenny, L. Galligan, Fergus J. Couch, Max Bylesjö, D. P. Harkin, Jennifer E. Quinn, Patrick G. Johnston, Steve Deharo, V. M. Farztdinov, Laura Hill, Nicolas Goffard, Timothy Davison
Publikováno v:
Journal of Clinical Oncology. 29:10511-10511
10511 Background: Loss of a functional DNA-damage response (DDR) sensitizes tumors to DNA-damaging as well as targeted therapeutics such as PARP-1 inhibitors. However, there is no assay to detect D...
Autor:
Richard D. Kennedy, Jude M. Mulligan, F. A. McDyer, Iris Halfpenny, Thomas F. DeLaney, Max Bylesjö, Jennifer E. Quinn, Fergus J. Couch, Paul Harkin, Vitali Proutski, Steve Deharo
Publikováno v:
Cancer Research. 71:326-326
Microarray gene expression profiling has facilitated identification of molecular subtypes which can be associated with disease outcome and treatment response. However current platforms lack disease focus, potentially missing vital information contain
Autor:
Iris Halfpenny, T. Delaney, Paul Harkin, Fergus J. Couch, V. Farztdinov, F.A. McDyer, Jennifer E. Quinn, Richard D. Kennedy, Jude M. Mulligan, P. Kerr
Publikováno v:
European Journal of Cancer Supplements. 7:21
Autor:
Iris Halfpenny, Anne M. Bowcock, Eva Tuomilehto-Wolf, Derek Middleton, Fionnuala Williams, Cindy Helms
Publikováno v:
Human Immunology. 65:S32
Publikováno v:
Human Immunology. 64:S166