Head-to-Head Comparison of Anti-Inflammatory Performance of Known Natural Products In Vitro.

Autor: Iris E Allijn, Stefan F C Vaessen, Linda C Quarles van Ufford, Kees J Beukelman, Menno P J de Winther, Gert Storm, Raymond M Schiffelers

Publikováno v: PLoS ONE, Vol 11, Iss 5, p e0155325 (2016)

Inflammation is an important therapeutic target. Due to their potency, steroidal drugs dominate the current treatment of inflammatory disorders. However, steroidal drugs can also exert a broad range of side effects and appear not always effective. Th

Externí odkaz: https://doaj.org/article/79f4248a165e48ffb801dd07a772cae0

Membranes for modelling cardiac tissue stiffness in vitro based on poly(Trimethylene carbonate) and poly(ethylene glycol) polymers

Autor: Robert Passier, André A. Poot, Iris E. Allijn, Marcelo C. Ribeiro, Dimitrios Stamatialis

Publikováno v: Membranes, 10(10):274, 1-12. Molecular Diversity Preservation International
Membranes
Volume 10
Issue 10
Membranes, Vol 10, Iss 274, p 274 (2020)

Despite the increased expenditure of the pharmaceutical industry on research and development, the number of drugs for cardiovascular diseases that reaches the market is decreasing. A major issue is the limited ability of the current in vitro and expe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea469c17b6130301e85478098087033
https://research.utwente.nl/en/publications/1878fe08-011c-40f5-918c-bb482b1e9afa

Environmental impact of switching from the synthetic glucocorticoid prednisolone to the natural alkaloid berberine

Autor: Ad M.J. Ragas, Iris E. Allijn, Rik Oldenkamp, Raymond M. Schiffelers, Gert Storm

Publikováno v: PLoS One, 13(6). Public Library of Science
PLoS One, 13, 1-15
PLoS ONE [E], 13(6). Public Library of Science
PLoS ONE, Vol 13, Iss 6, p e0199095 (2018)
PLoS ONE, 13(6):e0199095. Public Library of Science
Allijn, I E, Oldenkamp, R, Storm, G, Ragas, A M J & Schiffelers, R M 2018, ' Environmental impact of switching from the synthetic glucocorticoid prednisolone to the natural alkaloid berberine ', PLOS ONE, vol. 13, no. 6, 0199095 . https://doi.org/10.1371/journal.pone.0199095
PLOS ONE, 13(6):0199095. Public Library of Science
PLoS One, 13, 6, pp. 1-15
PLoS ONE

Low amounts of human pharmaceuticals in the aquatic environment can affect bacteria, animals and ultimately humans. Here, the environmental consequences of a shift in prescription behavior from prednisolone to berberine was modeled using an environme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb60d2b618b42cc1fed27b8c8c96aa0
https://dspace.library.uu.nl/handle/1874/375481

Natural products to target inflammation

Autor: Iris E. Allijn

Chapter 1 Most Western lifestyle diseases such as type 2 diabetes mellitus, cardiovascular disease and cancer have a chronic inflammatory process at its base. Therefore, inflammation is an important therapeutic target. Due to their potency, steroidal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b545f9621171fcd3ab9739be78ef0701
https://doi.org/10.3990/1.9789036542050

Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction

Autor: Suet Yen Chong, Josbert M. Metselaar, Iris E. Allijn, Carolyn S.P. Lam, Bertrand Czarny, Giorgia Pastorin, Jiong-Wei Wang, Acarilia Eduardo da Silva, Dominique P.V. de Kleijn, Marek Weiler, Gerrit Storm, Raymond M. Schiffelers, Xiaoyuan Wang

Publikováno v: Journal of Controlled Release, 247, 127. Elsevier
Journal of Controlled Release, 247, 127-133. Elsevier Bedrijfsinformatie b.v.
Journal of controlled release, 247, 127-133. Elsevier

Inflammation is a known mediator of adverse ventricular remodeling after myocardial infarction (MI) that may lead to reduction of ejection fraction and subsequent heart failure. Berberine is a isoquinoline quarternary alkaloid from plants that has be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5f766866f7446b35ea14cd153d1a92
https://doi.org/10.1016/j.jconrel.2016.12.042