Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Iris Caramalho"'
Autor:
Iris Caramalho, Paula Matoso, Dário Ligeiro, Tiago Paixão, Daniel Sobral, Ana Laura Fitas, Catarina Limbert, Jocelyne Demengeot, Carlos Penha-Gonçalves
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionEarly-onset Type 1 diabetes (EOT1D) is considered a disease subtype with distinctive immunological and clinical features. While both Human Leukocyte Antigen (HLA) and non-HLA variants contribute to age at T1D diagnosis, detailed analyses
Externí odkaz:
https://doaj.org/article/9c2c31772930482bbe946e8a148ecbe3
Autor:
Migla Miskinyte, Ana Sousa, Ricardo S Ramiro, Jorge A Moura de Sousa, Jerzy Kotlinowski, Iris Caramalho, Sara Magalhães, Miguel P Soares, Isabel Gordo
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12, p e1003802 (2013)
Antagonistic interactions are likely important driving forces of the evolutionary process underlying bacterial genome complexity and diversity. We hypothesized that the ability of evolved bacteria to escape specific components of host innate immunity
Externí odkaz:
https://doaj.org/article/2f9e1ddc011c4aca9168fd2c0497aac7
Autor:
Omer Dushek, Sabina Mueller, Sebastien Soubies, David Depoil, Iris Caramalho, Daniel Coombs, Salvatore Valitutti
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3913 (2008)
BACKGROUND: The activation of T lymphocytes by specific antigen is accompanied by the formation of a specialized signaling region termed the immunological synapse, characterized by the clustering and segregation of surface molecules and, in particula
Externí odkaz:
https://doaj.org/article/e2dd424b8e8d43dca84e50d1a448391b
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2559
Cellular adoptive transfer and mixed bone marrow chimera are cornerstone experimental tools for immuno-biology. Here we describe protocols for adoptive transfer and bone marrow chimera to address the effect of a specific mutation on T regulatory cell
Autor:
Andreia Fiúza Ribeiro, Ana Laura Fitas, Marcela Oliveira Pires, Paula Matoso, Dário Ligeiro, Daniel Sobral, Carlos Penha-Gonçalves, Jocelyne Demengeot, Íris Caramalho, Catarina Limbert
Publikováno v:
Journal of Diabetes Research, Vol 2024 (2024)
Conclusions: WES found potentially deleterious rare variants in MODY genes in 8.1% of EOT1D, occurring in the context of a T1D genetic background. Such genetic variants may contribute to disease precipitation by a β-cell dysfunction mechanism. This
Externí odkaz:
https://doaj.org/article/b2777bfd09e14d60ba14bbb7d23120ce
Autor:
Sara Bucar, André Dargen de Matos Branco, Márcia F. Mata, João Coutinho Milhano, Íris Caramalho, Joaquim M. S. Cabral, Ana Fernandes-Platzgummer, Cláudia L. da Silva
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Background Umbilical cord blood (UCB) is a clinically relevant alternative source of hematopoietic stem/progenitor cells (HSPC). To overcome the low cell number per UCB unit, ex vivo expansion of UCB HSPC in co-culture with mesenchymal strom
Externí odkaz:
https://doaj.org/article/f5f4c140897c48e9ac47d4ee5677c0ca
Publikováno v:
International immunology. 14(4)
Type I interferon (IFN-I) is constitutively produced in the bone marrow (BM), and induced at sites of inflammation and following infection by viruses or microorganisms. We have previously shown that IFN-I regulates the generation and selection of nor
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f06610cfd6212db95d0827fe4ff2fc84
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036206908&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036206908&partnerID=MN8TOARS