Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Iris Boraschi-Diaz"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Osteogenesis imperfecta (OI) is a rare bone disease that is associated with fractures and low bone mass. Sclerostin inhibition is being evaluated as a potential approach to increase bone mass in OI. We had previously found that in Col1a1 Jrt
Externí odkaz:
https://doaj.org/article/159067d733a54de487fe954a2d222d85
Publikováno v:
Data in Brief, Vol 41, Iss , Pp 107961- (2022)
Male and female mice with a dominant severe bone fragility disorder, osteogenesis imperfecta, and their wild-type littermates (FVB background) were challenged with a long-term (26 weeks) high-fat diet to evaluate the development of obesity and glucos
Externí odkaz:
https://doaj.org/article/055443d8bf3046b3818fd8ba397ec3fb
Skeletal Effects of Bone-Targeted TGFbeta Inhibition in a Mouse Model of Duchenne Muscular Dystrophy
Publikováno v:
Life, Vol 11, Iss 8, p 791 (2021)
Duchenne muscular dystrophy (DMD) is a severe progressive muscle disease that is frequently associated with secondary osteoporosis. Previous studies have shown that TGFbeta inactivating antibody improves the muscle phenotype in mdx mice, a model of D
Externí odkaz:
https://doaj.org/article/24208329d2b14873ae244265c532653f
Autor:
Larissa Sinkam, Iris Boraschi-Diaz, René B. Svensson, Michael Kjaer, Svetlana V. Komarova, Raynald Bergeron, Frank Rauch, Louis-Nicolas Veilleux
Publikováno v:
Sinkam, L, Boraschi-Diaz, I, Svensson, R B, Kjaer, M, Komarova, S V, Bergeron, R, Rauch, F & Veilleux, L N 2023, ' Tendon properties in a mouse model of severe osteogenesis imperfecta ', Connective Tissue Research, vol. 64, no. 3, pp. 285-293 . https://doi.org/10.1080/03008207.2022.2161376
Purpose/Aim of the study: Osteogenesis imperfecta is a heritable bone disorder that is usually caused by mutations in collagen type I encoding genes. The impact of such mutations on tendons, a structure with high collagen type I content, remains larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae7b9ed8c83a2737b7839189a252b33
https://pubmed.ncbi.nlm.nih.gov/36576243
https://pubmed.ncbi.nlm.nih.gov/36576243
Publikováno v:
Frontiers in Physics, Vol 5 (2017)
Collagens form the fibrous component of the extracellular matrix in all multi-cellular animals. Collagen type I is the most abundant collagen present in skin, tendons, vasculature, as well as the organic portion of the calcified tissue of bone and te
Externí odkaz:
https://doaj.org/article/03334fee3f6a4d8abf2f56603ab8f0b3
Publikováno v:
Data in brief. 41
Male and female mice with a dominant severe bone fragility disorder, osteogenesis imperfecta, and their wild-type littermates (FVB background) were challenged with a long-term (26 weeks) high-fat diet to evaluate the development of obesity and glucos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883c5296dbd84373eaf3b6e914f7a243
https://pubmed.ncbi.nlm.nih.gov/35242941
https://pubmed.ncbi.nlm.nih.gov/35242941
Autor:
Frank Rauch, Svetlana V. Komarova, Iris Boraschi-Diaz, Josephine T. Tauer, Mathieu Ferron, Omar Al Rifai
Publikováno v:
Molecular genetics and metabolism. 133(2)
Previously we have shown that young mice with a dominant severe form of osteogenesis imperfecta (OI), caused by mutated collagen type I, exhibit an altered glucose/insulin metabolism and energy expenditure along with elevated levels of osteocalcin, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805c7e65c42890c29c29b6908e8dc014
https://pubmed.ncbi.nlm.nih.gov/33814269
https://pubmed.ncbi.nlm.nih.gov/33814269
Publikováno v:
Bone. 148:115940
Osteogenesis imperfecta (OI) is a heritable connective tissue disorder that is most often caused by mutations in collagen type I encoding genes. Even though bone fragility is the most conspicuous finding in OI, the muscle system is also affected. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0619b4898f2850556a46dcb05fa332
https://doi.org/10.1016/j.bone.2021.115940
https://doi.org/10.1016/j.bone.2021.115940
Autor:
Frank Rauch, Iris Boraschi-Diaz
Publikováno v:
Bone Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12bce3e4dec430541a19d5347fa71157
https://doi.org/10.1530/boneabs.7.oc12
https://doi.org/10.1530/boneabs.7.oc12
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5290, p 5290 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5290, p 5290 (2021)
Volume 22
Issue 10
Osteogenesis imperfecta (OI) is a bone fragility disorder that is usually caused by mutations affecting collagen type I. We compared the calvaria bone tissue transcriptome of male 10-week-old heterozygous Jrt (Col1a1 mutation) and homozygous oim mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5910f9dcbb4015ce227eb941b53ce9c9
https://doi.org/10.3390/ijms22105290
https://doi.org/10.3390/ijms22105290