Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Iris Bickmeyer"'
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e23796 (2011)
Factors and mechanisms controlling lipometabolism homeostasis share a remarkable evolutionary conservation between humans and Drosophila flies. Accordingly, the Drosophila model has been successfully used to understand the pathophysiology of human me
Externí odkaz:
https://doaj.org/article/c7c5d2aa171c44b08d89ee4890d1e05e
Autor:
Martina Gáliková, Max Diesner, Reinhard Predel, Peter Klepsatel, Ronald P. Kühnlein, Iris Bickmeyer, Philip Hehlert, Yanjun Xu
Publikováno v:
Genetics
Maintenance of biological functions under negative energy balance depends on mobilization of storage lipids and carbohydrates in animals. In mammals, glucagon and glucocorticoid signaling mobilizes energy reserves, whereas adipokinetic hormones (AKHs
Autor:
Herbert Jäckle, Iris Bickmeyer, Jens Baumbach, Ronald P. Kühnlein, Martina Frank, Katarzyna M. Kowalczyk, Petra Hummel, Anja Hildebrandt, Dietmar Riedel, Konstantin Knorr
Publikováno v:
Cell Metabolism
SummaryTo unravel the evolutionarily conserved genetic network underlying energy homeostasis, we performed a systematic in vivo gene knockdown screen in Drosophila. We used a transgenic RNAi library enriched for fly orthologs of human genes to functi
Autor:
Iris Bickmeyer, Ruth Birner-Gruenberger, Philip Hehlert, Gerald N. Rechberger, Ronald P. Kühnlein, Albin Hermetter, Julia Lange, Manfred Kollroser
Publikováno v:
Insect Biochemistry and Molecular Biology
Carboxylesterases constitute a large enzyme family in insects, which is involved in diverse functions such as xenobiotic detoxi fi cation, lipid metabolism and reproduction. Phylogenetically, many insect carbox- ylesterases are represented by multien
Publikováno v:
Genetics
Drosophila melanogaster curled, one of the first fly mutants described by T. H. Morgan >90 years ago, is the founding member of a series of curled wing phenotype mutants widely used as markers in fruit fly genetics. The expressivity of the wing pheno