Non-Excitatory Amino Acids, Melatonin, and Free Radicals: Examining the Role in Stroke and Aging

Autor: Victoria Jiménez Carretero, Eva Ramos, Pedro Segura-Chama, Adan Hernández, Andrés M Baraibar, Iris Álvarez-Merz, Francisco López Muñoz, Javier Egea, José M. Solís, Alejandro Romero, Jesús M. Hernández-Guijo

Publikováno v: Antioxidants, Vol 12, Iss 10, p 1844 (2023)

The aim of this review is to explore the relationship between melatonin, free radicals, and non-excitatory amino acids, and their role in stroke and aging. Melatonin has garnered significant attention in recent years due to its diverse physiological

Externí odkaz: https://doaj.org/article/6ac299c5d2dd4c00a1866c42abd5efdc

Targeting harmful effects of non-excitatory amino acids as an alternative therapeutic strategy to reduce ischemic damage

Autor: Victoria Jiménez Carretero, Iris Álvarez-Merz, Jorge Hernández-Campano, Sergei A. Kirov, Jesús M. Hernández-Guijo

Publikováno v: Neural Regeneration Research, Vol 20, Iss 9, Pp 2454-2463 (2025)

The involvement of the excitatory amino acids glutamate and aspartate in cerebral ischemia and excitotoxicity is well-documented. Nevertheless, the role of non-excitatory amino acids in brain damage following a stroke or brain trauma remains largely

Externí odkaz: https://doaj.org/article/271eb48bba1e40748062ab522ad30dc9

The Coronavirus Disease 2019 (COVID-19): Key Emphasis on Melatonin Safety and Therapeutic Efficacy

Autor: Sakshi Painuli, Alejandro Romero, Natália Martins, Emilio Gil-Martín, Jesús M. Hernández-Guijo, Iris Álvarez-Merz, Javier Egea, Eva Ramos, Francisco López-Muñoz, Prabhakar Semwal

Publikováno v: Antioxidants, Vol 10, Iss 1152, p 1152 (2021)
Antioxidants
Investigo. Repositorio Institucional de la Universidade de Vigo
Universidade de Vigo (UVigo)

Viral infections constitute a tectonic convulsion in the normophysiology of the hosts. The current coronavirus disease 2019 (COVID-19) pandemic is not an exception, and therefore the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5cdb9f3394ebc74c8226640e0122c7
https://www.mdpi.com/2076-3921/10/7/1152

Intracellular accumulation of amino acids increases synaptic potentials in rat hippocampal slices

Autor: José M. Solís, Jose Carlos Gonzalez, Rafael Martín del Río, María-Dolores Muñoz, Javier G. Luengo, Iris Álvarez-Merz, Antonio S. Herranz, Jesús M. Hernández-Guijo

Publikováno v: Amino acids. 51(9)

The application of high concentrations of taurine induces long-lasting potentiation of synaptic responses and axon excitability. This phenomenon seems to require the contribution of a transport system with a low affinity for taurine. The prototypic t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9a671ac80073f0a7e11c8d570b8f4c
https://pubmed.ncbi.nlm.nih.gov/31428912

Ageing alters the kinetics of exocytosis of both wildtype and the 3xTg-AD mouse model of Alzheimer´s disease

Autor: Luis Gandía, Antonio G. García, Isabel Gameiro-Ros, Carmen Nanclares, Alicia Muñoz-Montero, Iris Álvarez-Merz, Inés Colmena, Andrés M. Baraibar

Publikováno v: IBJ Plus.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::afcc617c9f022d083af35014b1ffa539
https://doi.org/10.24217/2531-0151.18v1s1.00006