Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Iris, Scherwitzl"'
Autor:
Napas Taechasan, Iris Scherwitzl, Piyada Supasa, Wanwisa Dejnirattisai, Kanokwan Sriruksa, Wannee Limpitikul, Prida Malasit, Gavin R Screaton, Juthathip Mongkolsapaya, Thaneeya Duangchinda
Publikováno v:
Virus Research, Vol 345, Iss , Pp 199382- (2024)
Natural killer cells (NK cells) are the front line of immune cells to combat pathogens and able to influence the subsequent adaptive immune responses. One of the factors contributing to pathogenesis in dengue hemorrhagic fever (DHF) disease is aberra
Externí odkaz:
https://doaj.org/article/abe503051b1c4a7e90c6e2d90c4834bb
Autor:
Iris Scherwitzl, Silvana Opp, Alicia M. Hurtado, Christine Pampeno, Cynthia Loomis, Kasthuri Kannan, Minjun Yu, Daniel Meruelo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss , Pp 431-447 (2020)
Despite remarkable responses to cancer immunotherapy in a subset of patients, many patients remain resistant to therapies. It is now clear that elevated levels of tumor-infiltrating T cells as well as a systemic anti-tumor immune response are require
Externí odkaz:
https://doaj.org/article/75e61f4504cb4aaab669a71983399df6
Autor:
Iris Scherwitzl, Alicia Hurtado, Carolyn M. Pierce, Sandra Vogt, Christine Pampeno, Daniel Meruelo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 9, Iss , Pp 51-63 (2018)
Oncolytic viruses represent a promising form of cancer immunotherapy. We investigated the potential of Sindbis virus (SV) for the treatment of solid tumors expressing the human cancer testis antigen NYESO-1. NYESO-1 is an immunogenic antigen frequent
Externí odkaz:
https://doaj.org/article/e083e448bd424dfc9e27f7073be2f0af
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1 (2019)
BackgroundLimitations to current therapies for treating non-Hodgkin B cell lymphoma include relapse, toxicity and high cost. Thus, there remains a need for novel therapies. Oncolytic viral (OV) therapy has become a promising cancer immunotherapy beca
Externí odkaz:
https://doaj.org/article/1a9aafffaa05448f92fa8b5629b76110
Autor:
Bonnie van Wilgenburg, Iris Scherwitzl, Edward C. Hutchinson, Tianqi Leng, Ayako Kurioka, Corinna Kulicke, Catherine de Lara, Suzanne Cole, Sirijitt Vasanawathana, Wannee Limpitikul, Prida Malasit, Duncan Young, Laura Denney, STOP-HCV consortium, Michael D. Moore, Paolo Fabris, Maria Teresa Giordani, Ye Htun Oo, Stephen M. Laidlaw, Lynn B. Dustin, Ling-Pei Ho, Fiona M. Thompson, Narayan Ramamurthy, Juthathip Mongkolsapaya, Christian B. Willberg, Gavin R. Screaton, Paul Klenerman
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Mucosal Associated Invariant T cells have been implicated in response to bacterial pathogens. Here the authors show that in human viral infections, these cells are activated by IL-18 in cooperation with other pro-inflammatory cytokines, producing int
Externí odkaz:
https://doaj.org/article/cc3459afe5a047aa8c5feb665511a1eb
Autor:
Cynthia Loomis, Alicia Hurtado, Daniel Meruelo, Silvana Opp, Iris Scherwitzl, Christine Pampeno, Kasthuri Kannan, Minjun Yu
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss, Pp 431-447 (2020)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Despite remarkable responses to cancer immunotherapy in a subset of patients, many patients remain resistant to therapies. It is now clear that elevated levels of tumor-infiltrating T cells as well as a systemic anti-tumor immune response are require
Autor:
Sandra Vogt, Christine Pampeno, Carolyn M. Pierce, Daniel Meruelo, Iris Scherwitzl, Alicia Hurtado
Publikováno v:
Molecular Therapy: Oncolytics, Vol 9, Iss, Pp 51-63 (2018)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Oncolytic viruses represent a promising form of cancer immunotherapy. We investigated the potential of Sindbis virus (SV) for the treatment of solid tumors expressing the human cancer testis antigen NYESO-1. NYESO-1 is an immunogenic antigen frequent
Publikováno v:
Current Opinion in Virology. 23:95-101
Dengue (DENV), West Nile (WNV) and Zika (ZIKV) viruses are mosquito-transmitted flaviviruses that cause thousands of human deaths and millions of illnesses each year. In the last decades, epidemic outbreaks of all three flaviviruses emerged and cause
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1 (2019)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Background Limitations to current therapies for treating non-Hodgkin B cell lymphoma include relapse, toxicity and high cost. Thus, there remains a need for novel therapies. Oncolytic viral (OV) therapy has become a promising cancer immunotherapy bec
Autor:
Sophie, Ridewood, Cher-Pheng, Ooi, Belinda, Hall, Anna, Trenaman, Nadina Vasileva, Wand, Georgios, Sioutas, Iris, Scherwitzl, Gloria, Rudenko
Publikováno v:
Molecular Microbiology
Summary Trypanosoma brucei faces relentless immune attack in the mammalian bloodstream, where it is protected by an essential coat of Variant Surface Glycoprotein (VSG) comprising ∼10% total protein. The active VSG gene is in a Pol I‐transcribed