Advancing 89Zr-immuno-PET in neuroscience with a bispecific anti-amyloid-beta monoclonal antibody – the choice of chelator is essential

Autor: Thomas E. Wuensche, Natascha Stergiou, Iris Mes, Mariska Verlaan, Maxime Schreurs, Esther J. M. Kooijman, Bart Janssen, Albert D. Windhorst, Allan Jensen, Ayodeji A. Asuni, Benny Bang-Andersen, Wissam Beaino, Guus A. M. S. Dongen, Danielle J. Vugts

Publikováno v: Theranostics, 12(16), 7067-7079. Ivyspring International Publisher
Wuensche, T E, Stergiou, N, Mes, I, Verlaan, M, Schreurs, M, Kooijman, E J M, Janssen, B, Windhorst, A D, Jensen, A, Asuni, A A, Bang-Andersen, B, van Dongen, G A M S, Beaino, W & Vugts, D J 2022, ' Advancing 89Zr-immuno-PET in neuroscience with a bispecific anti-amyloid-beta monoclonal antibody – the choice of chelator is essential ', Theranostics, vol. 12, no. 16, pp. 7067-7079 . https://doi.org/10.7150/thno.73509

The accelerated approval of the monoclonal antibody (mAb) aducanumab as a treatment option for Alzheimer’s Disease and the continued discussions about its efficacy have shown that a better understanding of immunotherapy for the treatment of neurode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4d3375c16493f62b237d91b0a1ba2a
https://research.vumc.nl/en/publications/b7328b80-aecb-4811-90b2-07640111d96c

Development of 89Zr-antibody-PET imaging to evaluate improved brain targeting via transferrin receptor 1: the chelator matters

Autor: Thomas Wuensche, Natascha Stergiou, Iris Mes, Mariska Verlaan, Maxime Schreurs, Esther Kooijman, Bart Janssen, Albert Windhorst, Soren Christensen, Allan Jensen, Ayodeji Asuni, Benny Bang-Andersen, Wissam Beaino, Guus van Dongen, Danielle Vugts

Publikováno v: Nuclear Medicine and Biology. :S24

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b96dfe2d46f3bc2493a10ad576ea2feb
https://doi.org/10.1016/s0969-8051(22)00092-0