Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Iris, Gruska"'
Autor:
Boris Bogdanow, Max Schmidt, Henry Weisbach, Iris Gruska, Barbara Vetter, Koshi Imami, Eleonore Ostermann, Wolfram Brune, Matthias Selbach, Christian Hagemeier, Lüder Wiebusch
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Herpesviruses code for conserved protein kinases (CHPKs) that exert several regulatory functions by interacting with cellular factors. Here, the authors use affinity purification mass spectrometry (AP–MS) to identify differential interaction partne
Externí odkaz:
https://doaj.org/article/133fc29f23204b0791dbb8300482ea71
Autor:
Georgios Vavouras Syrigos, Maximilian Feige, Alicia Dirlam, Ramona Businger, Iris Gruska, Lüder Wiebusch, Klaus Hamprecht, Michael Schindler
Human cytomegalovirus (HCMV) is a herpesvirus that causes life-threatening infections in newborns or immunosuppressed patients. For viral replication, HCMV establishes a network of cellular interactions, among others cyclin-dependent kinases (CDK). F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa0a17897e4279feea2c1b0a784376bb
https://doi.org/10.1101/2023.02.01.526617
https://doi.org/10.1101/2023.02.01.526617
Autor:
Henry Weisbach, Christoph Schablowsky, Barbara Vetter, Iris Gruska, Christian Hagemeier, Lüder Wiebusch
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006193 (2017)
Generally, the antagonism between host restriction factors and viral countermeasures decides on cellular permissiveness or resistance to virus infection. Human cytomegalovirus (HCMV) has evolved an additional level of self-imposed restriction by the
Externí odkaz:
https://doaj.org/article/d18179255440463e9af29ac85d8eae9f
Autor:
Boris Bogdanow, Iris Gruska, Lars Mühlberg, Jonas Protze, Svea Hohensee, Barbara Vetter, Martin Lehmann, Lüder Wiebusch, Fan Liu
Herpesviruses assemble large enveloped particles that are difficult to characterize structurally due to their size, fragility and complex proteome with partially amorphous nature. Here we use cross-linking mass spectrometry and quantitative proteomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::180cf85f58d941b311836c7434a18482
https://doi.org/10.1101/2022.05.02.490278
https://doi.org/10.1101/2022.05.02.490278
Autor:
Henry Weisbach, Boris Bogdanow, Wolfram Brune, Max Schmidt, Koshi Imami, Lüder Wiebusch, Iris Gruska, Barbara Vetter, Christian Hagemeier, Eleonore Ostermann, Matthias Selbach
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Herpesviruses encode conserved protein kinases (CHPKs) to stimulate phosphorylation-sensitive processes during infection. How CHPKs bind to cellular factors and how this impacts their regulatory functions is poorly understood. Here, we use quantitati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0f25351c36cf7cba300b87b48c30b6
https://doaj.org/article/133fc29f23204b0791dbb8300482ea71
https://doaj.org/article/133fc29f23204b0791dbb8300482ea71
Autor:
Jens Milbradt, Andrea Schneider, Alexandra Herrmann, Thomas Gramberg, Melissa Kießling, Iris Gruska, Nerea Ferreirós, Sabine Wittmann, Janina Deutschmann, Thomas Winkler, Barbara Vetter, Lüder Wiebusch, Dominique Thomas, Michael Schindler
Publikováno v:
Nature Microbiology. 4:2273-2284
The deoxynucleotide triphosphate (dNTP) hydrolase SAMHD1 inhibits retroviruses in non-dividing myeloid cells. Although antiviral activity towards DNA viruses has also been demonstrated, the role of SAMHD1 during cytomegalovirus (CMV) infection remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a2d9b2406be567161ef66a50fad4f92
https://doi.org/10.1038/s41564-019-0529-z
https://doi.org/10.1038/s41564-019-0529-z
Autor:
Janina, Deutschmann, Andrea, Schneider, Iris, Gruska, Barbara, Vetter, Dominique, Thomas, Melissa, Kießling, Sabine, Wittmann, Alexandra, Herrmann, Michael, Schindler, Jens, Milbradt, Nerea, Ferreirós, Thomas H, Winkler, Lüder, Wiebusch, Thomas, Gramberg
Publikováno v:
Nature microbiology. 4(12)
The deoxynucleotide triphosphate (dNTP) hydrolase SAMHD1 inhibits retroviruses in non-dividing myeloid cells. Although antiviral activity towards DNA viruses has also been demonstrated, the role of SAMHD1 during cytomegalovirus (CMV) infection remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09514f9337681efdbce0e3f6f897b793
https://pubmed.ncbi.nlm.nih.gov/31548683
https://pubmed.ncbi.nlm.nih.gov/31548683
Autor:
Lueder Wiebusch, Jens Milbradt, Iris Gruska, Ramona Businger, Michael Schindler, Janina Deutschmann, Thomas Gramberg
Publikováno v:
Nature microbiology. 4(12)
The host restriction factor sterile alpha motif and histidine–aspartate domain-containing protein 1 (SAMHD1) is an important component of the innate immune system. By regulating the intracellular nucleotide pool, SAMHD1 influences cell division and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cc926271168bad788430e35362c7b5
https://pubmed.ncbi.nlm.nih.gov/31548682
https://pubmed.ncbi.nlm.nih.gov/31548682
Publikováno v:
Journal of Virology. 80:11686-11698
NF-κB plays an important role in the early cellular response to pathogens by activating genes involved in inflammation, immune response, and cell proliferation and survival. NF-κB is also utilized by many viral pathogens, like human cytomegalovirus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab0b5089731eeaca9ea4cfe97c3eee1
https://doi.org/10.1128/jvi.01168-06
https://doi.org/10.1128/jvi.01168-06
Autor:
Jutta Wagner, Iris Gruska, Barbara Vetter, Christian Hagemeier, Lüder Wiebusch, Christina Montag
Publikováno v:
Journal of virology. 85(21)
Many viruses antagonize tumor necrosis factor alpha (TNF-α) signaling in order to counteract its antiviral properties. One way viruses achieve this goal is to reduce TNF-α receptor 1 (TNFR1) on the surface of infected cells. Such a mechanism is als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4869417f6604e4a194e559514e17e79e
https://pubmed.ncbi.nlm.nih.gov/21880774
https://pubmed.ncbi.nlm.nih.gov/21880774