Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Iris, Bartels"'
Autor:
Ignacio Rodriguez-Polo, Sophie Mißbach, Stoyan Petkov, Felix Mattern, Anna Maierhofer, Iga Grządzielewska, Yuliia Tereshchenko, Daniel Urrutia-Cabrera, Thomas Haaf, Ralf Dressel, Iris Bartels, Rüdiger Behr
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Non-human primates (NHPs) are, due to their close phylogenetic relationship to humans, excellent animal models to study clinically relevant mutations. However, the toolbox for the genetic modification of NHPs is less developed than those for
Externí odkaz:
https://doaj.org/article/a91a5aa2c75a42bd99754c8131f457a6
Publikováno v:
Molecular Cytogenetics, Vol 11, Iss 1, Pp 1-5 (2018)
Abstract Background Down syndrome, typically caused by trisomy 21, may also be associated by duplications of the Down syndrome critical region (DSCR) on chromosome 21q22. However, patients with small duplications of DSCR without accompanying deletion
Externí odkaz:
https://doaj.org/article/d535d188fe484cd28b4eb8ac3816d931
Autor:
Michael Stauske, Ignacio Rodriguez Polo, Wadim Haas, Debbra Yasemin Knorr, Thomas Borchert, Katrin Streckfuss-Bömeke, Ralf Dressel, Iris Bartels, Malte Tiburcy, Wolfram-Hubertus Zimmermann, Rüdiger Behr
Publikováno v:
Cells, Vol 9, Iss 6, p 1349 (2020)
Non-human primates (NHP) are important surrogate models for late preclinical development of advanced therapy medicinal products (ATMPs), including induced pluripotent stem cell (iPSC)-based therapies, which are also under development for heart failur
Externí odkaz:
https://doaj.org/article/f1d71d0abb0041fc8ff434416b98ff68
Autor:
Daniel Urrutia-Cabrera, Iris Bartels, Ralf Dressel, Anna Maierhofer, Yuliia Tereshchenko, Iga Grządzielewska, Ignacio Rodriguez-Polo, Felix Mattern, Thomas Haaf, Stoyan Petkov, Sophie Mißbach, Rüdiger Behr
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports
Scientific Reports
Non-human primates (NHPs) are, due to their close phylogenetic relationship to humans, excellent animal models to study clinically relevant mutations. However, the toolbox for the genetic modification of NHPs is less developed than those for other sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db60fbd6c6afade3a2d78b00eeaaf4c
https://doaj.org/article/a91a5aa2c75a42bd99754c8131f457a6
https://doaj.org/article/a91a5aa2c75a42bd99754c8131f457a6
Autor:
Ignacio, Rodriguez-Polo, Michael, Stauske, Alexander, Becker, Iris, Bartels, Ralf, Dressel, Rüdiger, Behr
Publikováno v:
Primate Biology
Clinical application of regenerative therapies using embryonic or induced pluripotent stem cells is within reach. Progress made during recent years has encouraged researchers to address remaining open questions in order to finally translate experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b0d13cff54d506f69c34214aa6f8081
https://pubmed.ncbi.nlm.nih.gov/32110718
https://pubmed.ncbi.nlm.nih.gov/32110718
Autor:
Daniel Ortmann, Toshiyuki Araki, James E. Hudson, Vijayakumar Muppala, Malte Tiburcy, Dirk Ziebolz, Poh Loong Soong, Angelica Roa, Iris Bartels, Gordon Keller, David A. Elliott, Farah Raad, Roger A. Pederson, Wolfram-Hubertus Zimmermann, Rüdiger Behr, Mei-Ling Chang Liao, Ralf Dressel, Benjamin G. Neel
Publikováno v:
SSRN Electronic Journal.
Pluripotent stem cells (PSCs) can differentiate into all somatic cell lineages, but fail to form functional macro-scale heart muscle organoids in monolayer, suspension, or aggregate cultures. Here we show that human and non-human primate (NHP) PSCs h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10684f78511cd3e208b84924c4451c25
https://doi.org/10.2139/ssrn.3318931
https://doi.org/10.2139/ssrn.3318931
Publikováno v:
European Journal of Medical Genetics. 56:458-462
Distal deletion 9p is associated with gonadal dysfunction in XY individuals. Little is known about the gonadal function and fertility of XX females with this condition. We report on an affected 31-year-old infertile woman presenting with premature ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af03ef0381e88b3c20877a181e8ac78e
https://doi.org/10.1016/j.ejmg.2013.06.002
https://doi.org/10.1016/j.ejmg.2013.06.002
Autor:
Barbara Zoll, Ursula Dybowski, Silke Pauli, Peter Burfeind, Moneef Shoukier, Rudolf Funke, Iris Bartels, Thomas Schmidt
Publikováno v:
European Journal of Medical Genetics. 55:480-484
We report on monochorionic diamniotic male twins discordant for the trisomy 12p syndrome. Trisomy 12p mosaicism with a supernumerary der(12)(pter > q12) was detected in approximately 50% of lymphocytes in both children. Fluorescence in situ hybridisa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54dd0d84cf1caebe8a88688895abe618
https://doi.org/10.1016/j.ejmg.2012.05.004
https://doi.org/10.1016/j.ejmg.2012.05.004
Autor:
Bernd Auber, Julia Schröder, Knut Brockmann, Iris Bartels, Dagmar Weise, Moneef Shoukier, Barbara Zoll, Gabriela Salinas-Riester, Julia Wickert, Peter Burfeind, Birgit Zirn
Publikováno v:
American Journal of Medical Genetics Part A. :229-235
Interstitial deletions of the proximal chromosome 16q are rare. To date, only six cases with molecularly well-characterized microdeletions within this chromosomal region have been described. We report on a patient with severe psychomotor delay, dysmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b26e9108cd325247470794934d4401
https://doi.org/10.1002/ajmg.a.34387
https://doi.org/10.1002/ajmg.a.34387
Autor:
Thomas Liehr, Heike Nelle, Peter Burfeind, EA Alsat, Franco Laccone, C Thiels, Gabriela Salinas-Riester, Bernd Auber, Moneef Shoukier, Iris Bartels
Publikováno v:
Clinical Genetics. 77:593-597
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3376ee2c488571c0b278daa9c458bccb
https://doi.org/10.1111/j.1399-0004.2009.01363.x
https://doi.org/10.1111/j.1399-0004.2009.01363.x