Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Irina Yu Petrushanko"'
Autor:
Kseniya B. Varshavskaya, Irina Yu Petrushanko, Vladimir A. Mitkevich, Evgeny P. Barykin, Alexander A. Makarov
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
One of the hallmarks of Alzheimer's disease (AD) is the accumulation of beta-amyloid peptide (Aβ) leading to formation of soluble neurotoxic Aβ oligomers and insoluble amyloid plaques in various parts of the brain. Aβ undergoes post-translational
Externí odkaz:
https://doaj.org/article/23fc9da7609c45ee8497180a10858354
Autor:
Simone Fenk, Elizaveta V. Melnikova, Anastasia A. Anashkina, Yuri M. Poluektov, Pavel I. Zaripov, Vladimir A. Mitkevich, Yaroslav V. Tkachev, Lars Kaestner, Giampaolo Minetti, Heimo Mairbäurl, Jeroen S. Goede, Alexander A. Makarov, Irina Yu Petrushanko, Anna Bogdanova
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102535- (2022)
Fast changes in environmental oxygen availability translate into shifts in mitochondrial free radical production. An increase in intraerythrocytic reduced glutathione (GSH) during deoxygenation would support the detoxification of exogenous oxidants r
Externí odkaz:
https://doaj.org/article/fbef6507b3bf4807b5f733973d965bb3
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Exogenous RNases are selectively toxic to tumor cells. The reasons for this selectivity are not quite clear and should be searched for in the properties that distinguish malignant from normal cells. During onco-transformation, cells acquire propertie
Externí odkaz:
https://doaj.org/article/ea79ee7e34cb468ca230d17b438f3460
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Control over the Na,K-ATPase function plays a central role in adaptation of the organisms to hypoxic and anoxic conditions. As the enzyme itself does not possess O2 binding sites its oxygen-sensitivity is mediated by a variety of redox-sensitive modi
Externí odkaz:
https://doaj.org/article/3b837ad9b7d0400288c0d0ddcb010f06
Autor:
Irina Yu Petrushanko, Vladimir M Lobachev, Alexey S Kononikhin, Alexander A Makarov, Francois Devred, Hervé Kovacic, Aslan A Kubatiev, Philipp O Tsvetkov
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158726 (2016)
NOX5 protein, one of the most active generators of reactive oxygen species (ROS), plays an important role in many processes, including regulation of cell growth, death and differentiation. Because of its central role in ROS generation, it needs to be
Externí odkaz:
https://doaj.org/article/56f4ab44727242238ee5b58463f2109a
Autor:
Irina Yu. Petrushanko, Artem M. Tverskoi, Evgeny P. Barykin, Aleksandra V. Petrovskaya, Maria A. Strelkova, Olga G. Leonova, Anastasia A. Anashkina, Anna P. Tolstova, Alexei A. Adzhubei, Anna Yu. Bogdanova, Alexander A. Makarov, Vladimir A. Mitkevich
Publikováno v:
Cells, Vol 11, Iss 17, p 2753 (2022)
Beta-amyloid (Aβ) has a dual role, both as an important factor in the pathology of Alzheimer’s disease and as a regulator in brain physiology. The inhibitory effect of Aβ42 oligomers on Na,K-ATPase contributes to neuronal dysfunction in Alzheimer
Externí odkaz:
https://doaj.org/article/b59b71b531fe4e4fb32469fb7869285c
Autor:
Tatiana A. Seregina, Irina Yu. Petrushanko, Rustem S. Shakulov, Pavel I. Zaripov, Alexander A. Makarov, Vladimir A. Mitkevich, Alexander S. Mironov
Publikováno v:
Cells, Vol 11, Iss 17, p 2667 (2022)
Impaired lipopolysaccharide biosynthesis in Gram-negative bacteria results in the “deep rough” phenotype, which is characterized by increased sensitivity of cells to various hydrophobic compounds, including antibiotics novobiocin, actinomycin D,
Externí odkaz:
https://doaj.org/article/53cb7bbfbf0e42a7978d5db482e1a078
Publikováno v:
Biophysical Reviews. 15:183-197
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfe9cb0d582001bb3cceb9a049e266a2
https://doi.org/10.1007/s12551-023-01052-x
https://doi.org/10.1007/s12551-023-01052-x
Autor:
Anastasia A. Anashkina, Irina Yu. Petrushanko, Rustam H. Ziganshin, Yuriy L. Orlov, Alexei N. Nekrasov
Publikováno v:
Entropy, Vol 23, Iss 12, p 1647 (2021)
Background: Analyzing the local sequence content in proteins, earlier we found that amino acid residue frequencies differ on various distances between amino acid positions in the sequence, assuming the existence of structural units. Methods: We used
Externí odkaz:
https://doaj.org/article/3132c0ee008d4a538f06810fe1ec30a9
Autor:
Polina V. Shnaider, Irina Yu. Petrushanko, Olga I. Aleshikova, Nataliya A. Babaeva, Lev A. Ashrafyan, Ekaterina I. Borovkova, Julia E. Dobrokhotova, Ivan M. Borovkov, Victoria O. Shender, Elena Khomyakova
Publikováno v:
Frontiers in Cell and Developmental Biology. 11
Ovarian cancer is known to be the most lethal malignancy among all gynecological cancers affecting a large number of women worldwide. The treatment of ovarian cancer is challenging due to the high recurrence rate of the disease and is further complic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bde0791392fec010b7cc34b6f797352c
https://doi.org/10.3389/fcell.2023.1057484
https://doi.org/10.3389/fcell.2023.1057484