Výsledky vyhledávání - "Irina Yu Nikitina"

Akademický článek

Severe Tuberculosis in Humans Correlates Best with Neutrophil Abundance and Lymphocyte Deficiency and Does Not Correlate with Antigen-Specific CD4 T-Cell Response

Autor: Alexander V. Panteleev, Irina Yu Nikitina, Irina A. Burmistrova, George A. Kosmiadi, Tatyana V. Radaeva, Rasul B. Amansahedov, Pavel V. Sadikov, Yana V. Serdyuk, Elena E. Larionova, Tatef R. Bagdasarian, Larisa N. Chernousova, Vitaly V. Ganusov, Irina V. Lyadova

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

It is generally thought that Mycobacterium tuberculosis (Mtb)-specific CD4+ Th1 cells producing IFN-γ are essential for protection against tuberculosis (TB). In some studies, protection has recently been associated with polyfunctional subpopulation

Externí odkaz: https://doaj.org/article/cdecbc8bf74e45cb8984be6178d9687c

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Akademický článek

Antigen-Specific IFN-γ Responses Correlate with the Activity of M. tuberculosis Infection but Are Not Associated with the Severity of Tuberculosis Disease

Autor: Irina Yu. Nikitina, Alexander V. Panteleev, Ekaterina V. Sosunova, Natalya L. Karpina, Tatef R. Bagdasarian, Irina A. Burmistrova, Sofia N. Andreevskaya, Larisa N. Chernousova, Irina A. Vasilyeva, Irina V. Lyadova

Publikováno v: Journal of Immunology Research, Vol 2016 (2016)

IFN-γ is a key cytokine in antituberculosis (TB) defense. However, how the levels of its secretion affect M. tuberculosis (Mtb) infection is not clear. We have analyzed associations between IFN-γ responses measured in QuantiFERON®-TB Gold In-tube

Externí odkaz: https://doaj.org/article/c092f3fe1de44ecdb1a91ccbe90a8ce4

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Comparative performance of QuantiFERON-TB Gold versus skin test with tuberculosis recombinant allergen (Diaskintest) among patients with suspected pulmonary tuberculosis in Russia

Autor: Irina V. Lyadova, Olga V. Kasimceva, Natalya Karpina, Atadzhan Ergeshov, Vladislav Y. Gergert, Irina Yu. Nikitina

Publikováno v: International Journal of Infectious Diseases, Vol 86, Iss, Pp 18-24 (2019)

Background: The early identification of Mycobacterium tuberculosis infection can prevent tuberculosis (TB) transmission. A skin test with a tuberculosis recombinant allergen (Diaskintest) is a new method for identification that has been implemented i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2829e5c2770055c1a4eea7ece5ad426f
http://www.sciencedirect.com/science/article/pii/S1201971219302590

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Akademický článek

Mtb-specific CD27low CD4 T cells as markers of lung tissue destruction during pulmonary tuberculosis in humans.

Autor: Irina Yu Nikitina, Natalya A Kondratuk, George A Kosmiadi, Rasul B Amansahedov, Irina A Vasilyeva, Vitaly V Ganusov, Irina V Lyadova

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e43733 (2012)

Effector CD4 T cells represent a key component of the host's anti-tuberculosis immune defense. Successful differentiation and functioning of effector lymphocytes protects the host against severe M. tuberculosis (Mtb) infection. On the other hand, eff

Externí odkaz: https://doaj.org/article/ac7efb02161e404a844628d474c20afc

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Th1, Th17, and Th1Th17 Lymphocytes during Tuberculosis: Th1 Lymphocytes Predominate and Appear as Low-Differentiated CXCR3+CCR6+ Cells in the Blood and Highly Differentiated CXCR3+/−CCR6− Cells in the Lungs

Autor: Yana Serdyuk, Tatiana V. Radaeva, Irina V. Lyadova, Alexander A Nikolaev, George A. Kosmiadi, Lubov A. Gorelova, Irina Yu. Nikitina, Alexander V. Panteleev, Tatiana A. Nenasheva, Bozhenko Vk, Yana Yu. Kiseleva

Publikováno v: The Journal of Immunology. 200:2090-2103

Th1 lymphocytes are considered the main mediators of protection against tuberculosis (TB); however, their phenotypic characteristics and relationship with Th17 and Th1Th17 populations during TB are poorly understood. We have analyzed Th1, Th17, and T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a37cabb742b66d87e54b89f8bfa0861
https://doi.org/10.4049/jimmunol.1701424

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Non-invasive approach to diagnosis of pulmonary tuberculosis using microdroplets collected from exhaled air

Autor: Elena Larionova, Tatevik Bagdasaryan, Irina V. Lyadova, Irina Yu. Nikitina, Yuri M. Shlyapnikov, Irina Andrievskaya, Smirnova Tg, Victor N. Morozov, Elena A. Shlyapnikova, Alexander A Nikolaev, Andrei Y. Mikheev, Irina A. Burmistrova

Publikováno v: Journal of breath research. 12(3)

In this report we present a proof-of-principle study aimed at developing non-invasive diagnostics for pulmonary TB that are based on analyzing TB biomarkers in exhaled microdroplets of lung fluid (MLFs). Samples were collected on electrospun filters

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9183c12e02f71afe02e5cff8ca7ac224
https://pubmed.ncbi.nlm.nih.gov/29504513

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