Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Irina V. Panyutin"'
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Ionizing radiation (IR) is a known mutagen that is widely employed for medical diagnostic and therapeutic purposes. To study the extent of genetic variations in DNA caused by IR, we used IR-sensitive human embryonic stem cells (hESCs). Four hESC cell
Externí odkaz:
https://doaj.org/article/f8bc6e03f83c45a09cdb51706fa98e36
Publikováno v:
Stem Cells International, Vol 2012 (2012)
The sodium-iodine symporter (NIS) is expressed on the cell membrane of many thyroid cancer cells, and is responsible for the radioactive iodine accumulation. However, treatment of anaplastic thyroid cancer is ineffective due to the low expression of
Externí odkaz:
https://doaj.org/article/e972687ed1ae441ca663213d6c96affe
Autor:
Irina V. Panyutin, Paul G. Wakim, Roberto Maass-Moreno, William F. Pritchard, Ronald D. Neumann, Igor G. Panyutin
Publikováno v:
International journal of radiation biology.
We studied the effects of computed tomography (CT) scan irradiation on proliferation and differentiation of human embryonic stem cells (hESCs). It was reported that hESC is extremely radiosensitive; exposure of hESC in cultures to 1 Gy of ionizing ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc506126ec185c92987487858a2274c
https://pubmed.ncbi.nlm.nih.gov/36352506
https://pubmed.ncbi.nlm.nih.gov/36352506
Autor:
Christine Hanu, Burk W. Loeliger, Igor G. Panyutin, Ronald D. Neumann, Paul Wakim, Irina V. Panyutin, William F. Pritchard, Roberto Maass-Moreno
Publikováno v:
Radiat Res
Human embryonic brain development is highly sensitive to ionizing radiation. However, detailed information on the mechanisms of this sensitivity is not available due to limited experimental data. In this study, differentiation of human embryonic stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42db97b287e58e52e1cdc43ed6fa760b
https://pubmed.ncbi.nlm.nih.gov/32216708
https://pubmed.ncbi.nlm.nih.gov/32216708
Publikováno v:
Nature
Scientific Reports
Scientific Reports
We studied the effect of ionizing radiation (IR) on continuous growth of seven hESC lines. Cells were exposed to 0, 0.2, or 1 Gy of X-rays, and the growth rates of cell populations were assessed by measuring areas of the same individual colonies vers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4ae7fb6ba2d0d4f747658c01b98871
https://doi.org/10.1038/srep43995
https://doi.org/10.1038/srep43995
Publikováno v:
Mutation research.
We assessed single nucleotide variations (SNVs) between individual cells in two cancer cell lines; DU145, from brain metastasis of prostate tumor with deficient mismatch repair; and HT1080, a fibrosarcoma cell line. Clones of individual cells were is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db65be75ecb354c8fcd9853434550ad
https://pubmed.ncbi.nlm.nih.gov/28837838
https://pubmed.ncbi.nlm.nih.gov/28837838
Autor:
Ronald D. Neumann, Burk W. Loeliger, Igor G. Panyutin, Roberto Maass-Moreno, Christine Hanu, Irina V. Panyutin, William F. Pritchard, Paul Wakim
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 16
International Journal of Molecular Sciences, Vol 20, Iss 16, p 3900 (2019)
Volume 20
Issue 16
International Journal of Molecular Sciences, Vol 20, Iss 16, p 3900 (2019)
We studied the effect of radiation from computed tomography (CT) scans on differentiation of human embryonic stem cells (hESCs) into neuronal lineage. hESCs were divided into three radiation exposure groups: 0-dose, low-dose, or high-dose exposure. L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29441cd4b2001f9ffb672e6ef12d476b
https://doi.org/10.3390/ijms20163900
https://doi.org/10.3390/ijms20163900
Publikováno v:
Oligonucleotides. 20:277-284
The delivery of oligodeoxynucleotides (ODNs) into cells is widely utilized for antisense, antigene, aptamer, and similar approaches to regulate gene and protein activities based upon the ODNs' sequence-specific recognition. Short pieces of DNA can al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bc109de41700226f67c93c1de47ebc
https://doi.org/10.1089/oli.2010.0255
https://doi.org/10.1089/oli.2010.0255
Publikováno v:
Radiation Research. 168:493-498
DNA double-strand breaks are thought to precede the formation of most radiation-induced micronuclei. Phosphorylation of the histone H2AX is an early indicator of DNA double-strand breaks. Here we studied the phosphorylation status of the histone H2AX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1777c06a5062c24e0a28551a581a1000
https://doi.org/10.1667/rr0788.1
https://doi.org/10.1667/rr0788.1
Autor:
Petra Pfeiffer, Elke Feldmann, Wolfgang Goedecke, Christian Schunck, Ronald D. Neumann, Andrea Odersky, Igor G. Panyutin, Irina V. Panyutin, Guenter Obe
Publikováno v:
Journal of Biological Chemistry. 277:11756-11764
In mammalian cells, nonhomologous DNA end joining (NHEJ) is considered the major pathway of double-strand break (DSB) repair. Rejoining of DSB produced by decay of (125)I positioned against a specific target site in plasmid DNA via a triplex-forming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34bcaf98ce3b9e19f2ab3c9eb08dc02f
https://doi.org/10.1074/jbc.m111304200
https://doi.org/10.1074/jbc.m111304200