Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Irina V. Kovtun"'
Autor:
Faye R. Harris, Piyan Zhang, Lin Yang, Xiaonan Hou, Konstantinos Leventakos, Saravut J. Weroha, George Vasmatzis, Irina V. Kovtun
Publikováno v:
Molecular Oncology, Vol 13, Iss 2, Pp 132-152 (2019)
Ovarian cancer is the most lethal gynecologic malignancy. About 75% of ovarian cancer patients relapse and/or develop chemo‐resistant disease after initial response to standard‐of‐care treatment with platinum‐based therapies. HER2 amplificati
Externí odkaz:
https://doaj.org/article/96517e9183104d659c8a41dd206adf79
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142327 (2015)
Overexpression of TOP2A is associated with risk of systemic progression in prostate cancer patients, and higher levels of TOP2A were found in hormone-resistant cases. To elucidate the mechanism by which high levels of TOP2A contribute to tumor progre
Externí odkaz:
https://doaj.org/article/72ea0d28265947acb47f36aedf1c77d9
Autor:
R. Jeffrey Karnes, William R. Sukov, Faye R. Harris, Athanasios Gaitatzes, Sarah H. Johnson, James B. Smadbeck, Irina V. Kovtun, Stephen J. Murphy, John C. Cheville, Farhad Kosari, George Vasmatzis, Laureano J. Rangel, Sara M. Kloft-Nelson, Simone Terra, Shabnam Zarei, Patricia T. Greipp, Ryan A. Knudson, Darlene L. Knutson, Terry M. Therneau
Publikováno v:
Mayo Clinic Proceedings. 94:27-36
Objective To test the hypothesis that chromosomal rearrangements (CRs) can distinguish low risk of progression (LRP) from intermediate and high risk of progression (IHRP) to prostate cancer (PCa) and if these CRs have the potential to identify men wi
Autor:
Piyan Zhang, Irina V. Kovtun
Publikováno v:
Journal of visualized experiments : JoVE. (161)
We present here an integrative approach for testing efficacy of targeted therapies that combines the next generation sequencing technolo-gies, therapeutic target analyses and drug response monitoring using patient derived xenografts (PDX). This strat
Publikováno v:
Oncotarget
The mechanism of prostate cancer (PCa) progression towards the hormone refractory state remains poorly understood. Treatment options for such patients are limited and present a major clinical challenge. Previously, δ-catenin was reported to promote
Autor:
Prasuna Muppa, Geoffrey C. Halling, Mariza de Andrade, Nafiseh Janaki, Stephen J. Murphy, Kaustubh N. Bhinge, Farhad Kosari, Irina V. Kovtun, Simone Terra, Tobias Peikert, Aqsa Nasir, Hamed Rahi, Marie Christine Aubry, Lin Yang, Aaron S. Mansfield, George Vasmatzis, Ping Yang, Joanne Yi
Publikováno v:
Oncotarget
// Kaustubh Bhinge 1 , Lin Yang 2 , Simone Terra 6 , Aqsa Nasir 2 , Prasuna Muppa 6 , Marie Christine Aubry 6 , Joanne Yi 6 , Nafiseh Janaki 2 , Irina V. Kovtun 3 , Stephen J. Murphy 1 , Geoffrey Halling 1 , Hamed Rahi 1 , Aaron Mansfield 5 , Mariza
Autor:
Faye R. Harris, Saravut J. Weroha, Irina V. Kovtun, Xiaonan Hou, Konstantinos Leventakos, George Vasmatzis, Piyan Zhang, Lin Yang
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 13, Iss 2, Pp 132-152 (2019)
Molecular Oncology, Vol 13, Iss 2, Pp 132-152 (2019)
Ovarian cancer is the most lethal gynecologic malignancy. About 75% of ovarian cancer patients relapse and/or develop chemo-resistant disease after initial response to standard-of-care treatment with platinum-based therapies. HER2 amplifications and
Publikováno v:
Oncotarget
Massive genomic rearrangements, a result of single catastrophic event termed chromothrispsis or chromosomal catastrophe, have been identified in a variety of human cancers. In a few cancer types, chromothripsis was found to be associated with poor pr
Autor:
Farhad Kosari, Dennis A. Wigle, Stephen J. Murphy, Marie Christine Aubry, Sandra C. Tomaszek, Cristiane M. Ida, Sibel Erdogan, L. C. Bolette, Janet L. Schaefer Klein, Irina V. Kovtun, Ping Yang, C. P. Kolbert, Lin Yang, Yafei Li, George Vasmatzis
Publikováno v:
Oncogene. 33:3776-3783
ASCL1 is an important regulatory transcription factor in pulmonary neuroendocrine (NE) cell development, but its value as a biomarker of NE differentiation in lung adenocarcinoma (AD) and as a potential prognostic biomarker remains unclear. We examin
Autor:
Tobias Peikert, Irina V. Kovtun, George Vasmatzis, Prasuna Muppa, Kaustubh N. Bhinge, Marie-Christine Aubry, Stephen J. Murphy, Farhad Kosari, Lin Yang, Aaron S. Mansfield
Publikováno v:
Journal of Thoracic Oncology. 13:S586