Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Irina Shchaveleva"'
Autor:
Jimson W D'Souza, Smitha Reddy, Lisa E Goldsmith, Irina Shchaveleva, James D Marks, Samuel Litwin, Matthew K Robinson
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112376 (2014)
Inappropriate signaling through the epidermal growth factor receptor family (EGFR1/ERBB1, ERBB2/HER2, ERBB3/HER3, and ERBB4/HER4) of receptor tyrosine kinases leads to unregulated activation of multiple downstream signaling pathways that are linked t
Externí odkaz:
https://doaj.org/article/de2f6ddec96a48f9bca90652df0b0d87
Autor:
Kerry S. Campbell, Irina Shchaveleva, Lori J. Goldstein, Elias Obeid, Alex W McFarlane, Judy Fang, Shauna Souchuck
Publikováno v:
Cancer Research. 81:PS12-19
Background: PD-1 blockade has shown promising clinical activity in mTNBC. We designed an investigator-initiated multi-center clinical trial consisting of a Safety run-in, into a randomized phase II trial of combination pembrolizumab (P) with carbopla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c992eee2c8e60f5788f7cfee02d2648
https://doi.org/10.1158/1538-7445.sabcs20-ps12-19
https://doi.org/10.1158/1538-7445.sabcs20-ps12-19
Autor:
Gary D. Kruh, Heiner Westphal, Renxue Wang, Zhe-Sheng Chen, Anthony Lerro, Andres J. Klein-Szanto, Irina Shchaveleva, Alex Grinberg, Paul A. Dawson, Victor Ling, Martin G. Belinsky, Lisa J. Bain
Publikováno v:
Molecular Pharmacology. 68:160-168
Multidrug resistance protein 3 (MRP3) is an ATP-binding cassette transporter that is able to confer resistance to anticancer agents such as etoposide and to transport lipophilic anions such as bile acids and glucuronides. These capabilities, along wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4fc49255e33c9e34ba07ed543a1229
https://doi.org/10.1124/mol.104.010587
https://doi.org/10.1124/mol.104.010587
Publikováno v:
Cancer Research. 64:4927-4930
The multidrug resistance protein (MRP) family consists of nine members that can be categorized according to whether or not a third (NH2-terminal) membrane-spanning domain is present. Three (MRP1, MRP2, and MRP3) of the four members that have this str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4557b77139dc69c6ca96b0655b37f7a3
https://doi.org/10.1158/0008-5472.can-03-3111
https://doi.org/10.1158/0008-5472.can-03-3111
Autor:
Matthew K. Robinson, Å L Sundberg, M. von Mehren, Maria Russeva, Calvin Shaller, Irina Shchaveleva, Gregory P. Adams, Eva M. Horak, James D. Marks, K M Hodge, Heidi H. Simmons
Publikováno v:
British journal of cancer, vol 99, iss 9
British Journal of Cancer
British Journal of Cancer
Inappropriate signalling through the EGFR and ErbB2/HER2 members of the epidermal growth factor family of receptor tyrosine kinases is well recognised as being causally linked to a variety of cancers. Consequently, monoclonal antibodies specific for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f290a4d28a0dcc2d001882f3af9674
https://escholarship.org/uc/item/2dv7930d
https://escholarship.org/uc/item/2dv7930d
Autor:
Elena Kotova, James M. Gallo, Ping Guo, Andres Klein-Szanto, Gary D. Kruh, Alex Grinberg, Irina Shchaveleva, Feng Zhou, Heiner Westphal, Kun Lee, Martin G. Belinsky
Publikováno v:
Cancer research. 67(1)
Nucleoside-based analogues are mainstays in the treatment of cancer, viral infections, and inflammatory diseases. Recent studies showing that the ATP-binding cassette transporter, multidrug resistance protein 4, is able to efflux nucleoside and nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c15fc61cc4bf3123ed36a1c869c4be6
https://pubmed.ncbi.nlm.nih.gov/17210706
https://pubmed.ncbi.nlm.nih.gov/17210706
Autor:
Elizabeth, Hopper-Borge, Zhe-Sheng, Chen, Irina, Shchaveleva, Martin G, Belinsky, Gary D, Kruh
Publikováno v:
Cancer research. 64(14)
The multidrug resistance protein (MRP) family consists of nine members that can be categorized according to whether or not a third (NH(2)-terminal) membrane-spanning domain is present. Three (MRP1, MRP2, and MRP3) of the four members that have this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8566990ca79bd3c82403238b2375f2fe
https://pubmed.ncbi.nlm.nih.gov/15256465
https://pubmed.ncbi.nlm.nih.gov/15256465
Autor:
Zhe-Sheng, Chen, Robert W, Robey, Martin G, Belinsky, Irina, Shchaveleva, Xiao-Qin, Ren, Yoshikazu, Sugimoto, Douglas D, Ross, Susan E, Bates, Gary D, Kruh
Publikováno v:
Cancer research. 63(14)
ABCG2 is a plasma membrane efflux pump that is able to confer resistance to several anticancer agents, including mitoxantrone, camptothecins, anthracyclines, and flavopiridol. The antimetabolite methotrexate (MTX) was inferred recently to be an addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80d0021f4f27ce911dd95d1fb0a74ae0
https://pubmed.ncbi.nlm.nih.gov/12874005
https://pubmed.ncbi.nlm.nih.gov/12874005
Publikováno v:
Cancer research. 62(21)
Mutations in human multidrug resistance protein 6 (MRP6, ABCC6), a member of the MRP family of drug efflux pumps, are the genetic basis of Pseudoxanthoma elasticum, a disease that affects elastin fibers in the skin, retina, and blood vessels. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c96c795b6cbe2df1017cb7a0ca85385
https://pubmed.ncbi.nlm.nih.gov/12414644
https://pubmed.ncbi.nlm.nih.gov/12414644
Autor:
James D. Marks, Smitha Reddy, Matthew K. Robinson, Jimson W. D’Souza, Samuel Litwin, Lisa E. Goldsmith, Irina Shchaveleva
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e112376 (2014)
PLoS ONE, Vol 9, Iss 11, p e112376 (2014)
Background Inappropriate signaling through the epidermal growth factor receptor family (EGFR1/ERBB1, ERBB2/HER2, ERBB3/HER3, and ERBB4/HER4) of receptor tyrosine kinases leads to unregulated activation of multiple downstream signaling pathways that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dbe1fa74a40ada3399ae48950d1b2c
https://doi.org/10.1371/journal.pone.0112376
https://doi.org/10.1371/journal.pone.0112376