Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Irina Serova"'
TAD border deletion at the Kit locus causes tissue-specific ectopic activation of a neighboring gene
Autor:
Evelyn Kabirova, Anastasiya Ryzhkova, Varvara Lukyanchikova, Anna Khabarova, Alexey Korablev, Tatyana Shnaider, Miroslav Nuriddinov, Polina Belokopytova, Alexander Smirnov, Nikita V. Khotskin, Galina Kontsevaya, Irina Serova, Nariman Battulin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Topologically associated domains (TADs) restrict promoter-enhancer interactions, thereby maintaining the spatiotemporal pattern of gene activity. However, rearrangements of the TADs boundaries do not always lead to significant changes in the
Externí odkaz:
https://doaj.org/article/15cb7925751a4aab881fdbd3b131169d
Autor:
Paul Salnikov, Alexey Korablev, Irina Serova, Polina Belokopytova, Aleksandra Yan, Yana Stepanchuk, Savelii Tikhomirov, Veniamin Fishman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Structural variations are a pervasive feature of human genomes, and there is growing recognition of their role in disease development through their impact on spatial chromatin architecture. This understanding has led us to investigate the cl
Externí odkaz:
https://doaj.org/article/263e32d129b64302811266ca5797ce8c
Autor:
Irina Serova
Publikováno v:
The Global Psychotherapist, Vol 4, Iss 1, Pp 91-99 (2024)
The purpose of the article is to highlight the areas of business where positive psychotherapy can be applied in order to improve the business environment and to transform it into a more supportive, developing and less damaging area. The author’s ex
Externí odkaz:
https://doaj.org/article/4f043baefb714d2c87ab22ce7b2c9154
Autor:
Nariman Battulin, Vladimir M. Kovalzon, Alexey Korablev, Irina Serova, Oxana O. Kiryukhina, Marta G. Pechkova, Kirill A. Bogotskoy, Olga S. Tarasova, Yuri Panchin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5269 (2021)
In humans and other vertebrates pannexin protein family was discovered by homology to invertebrate gap junction proteins. Several biological functions were attributed to three vertebrate pannexins members. Six clinically significant independent varia
Externí odkaz:
https://doaj.org/article/a17cd256f80d44c195bb33e22a73775c
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3604 (2020)
Genome engineering has been tremendously affected by the appearance of the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (CRISPR/Cas9)-based approach. Initially discovered as an adaptive immune system
Externí odkaz:
https://doaj.org/article/eb094f4236d94ca5af037f82cda5dce3
Autor:
Oleg Serov, Irina Serova
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 76, Iss 3, Pp 529-540 (2004)
The past decade has witnessed immense progress in research into the molecular basis behind the developmental regulation of genes. Sets of genes functioning under hierarchical control have been identified, evolutionary conserved systems of genes effec
Externí odkaz:
https://doaj.org/article/e671a11363a7445ab86984fcb57c3dd4
Autor:
Irina Serova
Publikováno v:
Terapevt (General Physician). :31-36
The use of phytoestrogens in women during the menopausal transition and postmenopause. Phytoestrogens in the correction of age-related changes in a woman’s body and oxidative stress is one of the priorit y tasks of anti-aging medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4543e643f8b6cecd268e611fd2081bb7
https://doi.org/10.33920/med-12-2301-04
https://doi.org/10.33920/med-12-2301-04
Autor:
Nariman Battulin, Alexey Korablev, Anastasia Ryzhkova, Alexander Smirnov, Evelyn Kabirova, Anna Khabarova, Timofey Lagunov, Irina Serova, Oleg Serov
Publikováno v:
Transgenic Research. 31:525-535
In this work, we set out to create mice susceptible to the SARS-CoV-2 coronavirus. To ensure the ubiquitous expression of the human ACE2 gene we used the human EF1a promoter. Using pronuclear microinjection of the transgene construct, we obtained six
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9e2ba749db153206321d3d4ab0a539
https://doi.org/10.1007/s11248-022-00319-5
https://doi.org/10.1007/s11248-022-00319-5
Autor:
Evelyn Kabirova, Anastasiya Ryzhkova, Varvara Lukyanchikova, Anna Khabarova, Alexey Korablev, Tatyana Shnaider, Miroslav Nuriddinov, Polina Belokopytova, Galina Kontsevaya, Irina Serova, Nariman Battulin
Topologically associated domains (TADs) restrict promoter-enhancer interactions, thereby maintaining the spatiotemporal pattern of gene activity. However, rearrangements of the TADs boundaries do not always lead to significant changes in the activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecf8ac47813432c1853383e11796dc1c
https://doi.org/10.1101/2022.12.29.522177
https://doi.org/10.1101/2022.12.29.522177
Autor:
Irina Serova
Publikováno v:
St.Tikhons' University Review. Series IV. Pedagogy. Psychology. 41:106-117
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48d6e0934167787ea985a6a42a0029fb
https://doi.org/10.15382/sturiv201641.106-117
https://doi.org/10.15382/sturiv201641.106-117