Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Irina Schäfer"'
Autor:
Katharina Wagner, Frederik Damm, Felicitas Thol, Gudrun Göhring, Kerstin Görlich, Michael Heuser, Irina Schäfer, Brigitte Schlegelberger, Gerhard Heil, Arnold Ganser, Jürgen Krauter
Publikováno v:
Haematologica, Vol 96, Iss 5 (2011)
Background Several genetic aberrations with prognostic impact in first-line therapy have been described in patients with acute myeloid leukemia and normal karyotype. However, little is known about the influence of these aberrations on outcome after r
Externí odkaz:
https://doaj.org/article/65a51de4c2b047e195e18f9d740e1bc3
Autor:
Gudrun Göhring, Manuela Zucknick, Kerstin Görlich, Katharina Wagner, Gerhard Heil, Arnold Ganser, Wolfram Brugger, Brigitte Schlegelberger, Aruna Raghavachar, Irina Schäfer, Lothar Kanz, Michael Heuser, Günter Schlimok, Michael Lübbert, Oliver G. Ottmann, Jürgen Krauter, Hartmut Kirchner, Walter Fiedler, Wolfgang Heit, Frederik Damm
Publikováno v:
Journal of Clinical Oncology. 28:2356-2364
Purpose We assessed the prognostic impact of IDH1 R132 mutations and a known single nucleotide polymorphism (SNP) located in the same exon of the IDH1 gene in patients with cytogenetically normal acute myeloid leukemia (CN-AML) in the context of othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3d8262f4958e95050bf475fc73e7c8
https://doi.org/10.1200/jco.2009.27.6899
https://doi.org/10.1200/jco.2009.27.6899
Autor:
Kerstin Görlich, Irina Schäfer, Arnold Ganser, Frederik Damm, Brigitte Schlegelberger, Gudrun Göhring, Jürgen Krauter, Gerhard Heil, Felicitas Thol, Katharina Wagner, Michael Heuser
Publikováno v:
Haematologica. 96(5)
Background Several genetic aberrations with prognostic impact in first-line therapy have been described in patients with acute myeloid leukemia and normal karyotype. However, little is known about the influence of these aberrations on outcome after r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b69646e8c90be0ec097d2c69a003f4
https://pubmed.ncbi.nlm.nih.gov/21531946
https://pubmed.ncbi.nlm.nih.gov/21531946
Autor:
Cristina Sauerland, Claus Meyer, Konstanze Döhner, Katharina Wagner, Jürgen Krauter, Dietger Niederwieser, Gerhard Heil, Thomas Büchner, Hartmut Döhner, Gerhard Ehninger, Arnold Ganser, Brigitte Schlegelberger, Rolf Marschalek, Rainer Krahl, Richard F. Schlenk, Irina Schäfer, Markus Schaich
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 27(18)
Purpose To identify risk factors for induction success and overall survival (OS) and relapse-free survival (RFS) and to evaluate the impact of allogeneic stem-cell transplantation (alloSCT) in adult patients up to 60 years old with acute myeloid leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7066d7eec670f0e9406816963126b4e0
https://pubmed.ncbi.nlm.nih.gov/19380453
https://pubmed.ncbi.nlm.nih.gov/19380453
Autor:
Karl Welte, Ludwig Hoy, Manuela Germeshausen, Cornelia Zeidler, Peter Vandenberghe, Martin Zimmermann, Irina Schäfer
Publikováno v:
Blood. 118:1106-1106
Abstract 1106 Congenital neutropenia (CN) is well known as one of the premalignant bone marrow failure syndromes with an overall incidence of secondary leukemia of more than 10 percent. With the identification of new causative gene mutations the numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6a9b71d58ef92c595bdd512ca489d3f
https://doi.org/10.1182/blood.v118.21.1106.1106
https://doi.org/10.1182/blood.v118.21.1106.1106
Autor:
Arnold Ganser, Gerhard Ehninger, Brigitte Schlegelberger, Claus Meyer, Markus Schaich, Jürgen Krauter, Hartmut Döhner, Cristina Sauerland, Dietger Niederwieser, Konstanze Döhner, Rolf Marschalek, Katharina Wagner, Irina Schäfer, Richard F. Schlenk, Gerhard Heil, Thomas Büchner, Rainer Krahl
Publikováno v:
Blood. 110:759-759
The MLL gene on chromosome 11q23 is translocated to a variety of fusion partners in about 5–10% of adults with acute myeloid leukemia (AML). The heterogeneity of these genetic aberrations hampers risk stratification of the patients. To identify pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f18657c49b35a85cf0c3f071e759d6db
https://doi.org/10.1182/blood.v110.11.759.759
https://doi.org/10.1182/blood.v110.11.759.759
Autor:
Michael A. Morgan, Lars Bullinger, Andrea Corbacioglu, Hartmut Döhner, Stefan Fröhling, Arnold Ganser, Daniela Späth, Jürgen Krauter, Konstanze Döhner, Richard F. Schlenk, Irina Schäfer
Publikováno v:
Blood. 108:4-4
Background: Mutations in the genes encoding NPM1, FLT3 (FLT3 ITD, FLT3 TKD), CEBPA, MLL (PTD) and NRAS have been identified as molecular markers in acute myeloid leukemia (AML) exhibiting a normal karyotype. Most recent studies focused on the prognos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e98568a0d62a856db378cf76a5d3912
https://doi.org/10.1182/blood.v108.11.4.4
https://doi.org/10.1182/blood.v108.11.4.4
Autor:
Rolf Marschalek, Claus Meyer, Arnold Ganser, Jürgen Krauter, Katharina Wagner, Hartmut Döhner, Gerhard Heil, Gerhard Ehninger, Dietger Niederwieser, Richard F. Schlenk, Rainer Krahl, Konstanze Döhner, Markus Schaich, Irina Schäfer
Publikováno v:
Blood. 108:16-16
Aberrations of the MLL gene on chromosome 11q23 occur in about 5–10% of adult patients with acute myeloid leukemia (AML). Most frequently, the MLL gene is fused to the genes AF9 on chromosome 9 or AF6 on chromosome 6 resulting in the translocation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dc57ffdf323e4e8532ceaf9ae1fb374
https://doi.org/10.1182/blood.v108.11.16.16
https://doi.org/10.1182/blood.v108.11.16.16
Autor:
Jutta Engel, Silke Soucek, Richard F. Schlenk, Irina Schäfer, Markus Schaich, Hartmut Döhner, Jörg Hasford, Claire Schleich, Gerhard Ehninger, Jürgen Krauter, Thomas Büchner, Dietger Niederwieser, Rainer Krahl, D. Messerer, Arnold Ganser, Christina Sauerland
Publikováno v:
Blood. 106:747-747
The impact of allogeneic blood stem cell transplantation (Allo-SCT) in comparison to conventional chemotherapy (CCT) in AML on quality of life remains unclear mainly due to a lack of studies with long term follow-up. Therefore the German AML-Intergro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cc28fa42014241a7a6feae8ffb087da
https://doi.org/10.1182/blood.v106.11.747.747
https://doi.org/10.1182/blood.v106.11.747.747
Autor:
Richard F. Schlenk, Stefan Fröhling, Konstanze Döhner, Juan Du, Hartmut Döhner, Jürgen Krauter, Andrea Corbacioglu, Daniela Späth, Arnold Ganser, Irina Schäfer
Publikováno v:
Blood. 106:2352-2352
Recently, mutations in the CEBPA gene, encoding CCAAT/enhancer binding protein alpha have been identified in 10 to 15% of patients with acute myeloid leukemia (AML) exhibiting a normal karyotype and mutant CEBPA was shown to predict favorable outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51888e20a604466509984f300dacd767
https://doi.org/10.1182/blood.v106.11.2352.2352
https://doi.org/10.1182/blood.v106.11.2352.2352