Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Irina Podolsky"'
Autor:
Stephen A Ramsey, Yuliya Vengrenyuk, Prashanthi Menon, Irina Podolsky, Jonathan E Feig, Alan Aderem, Edward A Fisher, Elizabeth S Gold
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004828 (2014)
We report the first systems biology investigation of regulators controlling arterial plaque macrophage transcriptional changes in response to lipid lowering in vivo in two distinct mouse models of atherosclerosis regression. Transcriptome measurement
Externí odkaz:
https://doaj.org/article/500b8774cff3460195cf16c1d57a6762
Autor:
Jyrki Selinummi, Pekka Ruusuvuori, Irina Podolsky, Adrian Ozinsky, Elizabeth Gold, Olli Yli-Harja, Alan Aderem, Ilya Shmulevich
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7497 (2009)
Fluorescence microscopy is the standard tool for detection and analysis of cellular phenomena. This technique, however, has a number of drawbacks such as the limited number of available fluorescent channels in microscopes, overlapping excitation and
Externí odkaz:
https://doaj.org/article/4e0f895ad0d64013b1444a97627c28b9
Autor:
Alan Aderem, Jeffrey A. Ranish, Stephen A. Ramsey, Elizabeth S. Gold, Irina Podolsky, Mark A. Gillespie
Publikováno v:
The EMBO Journal. 34:1244-1258
LXR–cofactor complexes activate the gene expression program responsible for cholesterol efflux in macrophages. Inflammation antagonizes this program, resulting in foam cell formation and atherosclerosis; however, the molecular mechanisms underlying
Autor:
Antti Niemistö, Alan Aderem, M. Kristina Hamilton, Jacques J. Peschon, Owen M. Siggs, Daniel E. Zak, Kathleen A. Kennedy, Shannon G. Fallen, Bruce Beutler, Rosa Suen, Elizabeth S. Gold, Joe S. Valvo, Frank Schmitz, Carrie D. Johnson, Tetyana Stolyar, Alan H. Diercks, Irina Podolsky
Publikováno v:
Proceedings of the National Academy of Sciences. 108:11536-11541
Precise control of the innate immune response is essential to ensure host defense against infection while avoiding inflammatory disease. Systems-level analyses of Toll-like receptor (TLR)-stimulated macrophages suggested that SHANK-associated RH doma
Autor:
Alan H. Diercks, Piper M. Treuting, Alan Aderem, Peter S. Askovich, Elizabeth S. Gold, Rebecca L. Podyminogin, Irina Podolsky
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(29)
Cross-talk between sterol regulatory pathways and inflammatory pathways has been demonstrated to significantly impact the development of both atherosclerosis and infectious disease. The oxysterol 25-hydroxycholesterol (25HC) plays multiple roles in l
Autor:
Elizabeth S. Gold, Adrian Ozinsky, Irina Podolsky, Olli Yli-Harja, Alan Aderem, Pekka Ruusuvuori, Jyrki Selinummi, Ilya Shmulevich
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 10, p e7497 (2009)
PLoS ONE, Vol 4, Iss 10, p e7497 (2009)
Background Fluorescence microscopy is the standard tool for detection and analysis of cellular phenomena. This technique, however, has a number of drawbacks such as the limited number of available fluorescent channels in microscopes, overlapping exci