Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Irina O, Vvedenskaya"'
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100858- (2021)
Summary: XACT-seq (“crosslink between active-center and template sequencing”) is a technique for high-throughput, single-nucleotide resolution mapping of RNA polymerase (RNAP) active-center positions relative to the DNA template. XACT-seq overcom
Externí odkaz:
https://doaj.org/article/4c467370ecb443ceba0f0b5bbb52089f
Autor:
Tingting Zhao, Irina O Vvedenskaya, William KM Lai, Shrabani Basu, B Franklin Pugh, Bryce E Nickels, Craig D Kaplan
Publikováno v:
eLife, Vol 10 (2021)
In Saccharomyces cerevisiae, RNA polymerase II (Pol II) selects transcription start sites (TSSs) by a unidirectional scanning process. During scanning, a preinitiation complex (PIC) assembled at an upstream core promoter initiates at select positions
Externí odkaz:
https://doaj.org/article/37c27916ae4b45b0b114094caef6209f
Autor:
Anna A. Shiriaeva, Ekaterina Savitskaya, Kirill A. Datsenko, Irina O. Vvedenskaya, Iana Fedorova, Natalia Morozova, Anastasia Metlitskaya, Anton Sabantsev, Bryce E. Nickels, Konstantin Severinov, Ekaterina Semenova
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Primed adaptation in the CRISPR-Cas system helps recognition of previously encountered sequence elements and promotes the formation of new memories. Here the authors characterized spacer precursors of type I-E and type I-F CRISPR-Cas system using in
Externí odkaz:
https://doaj.org/article/2843ec11149841ccb9221461a5c00330
Autor:
Valdir C. Barth, Ju-Mei Zeng, Irina O. Vvedenskaya, Ming Ouyang, Robert N. Husson, Nancy A. Woychik
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
MazF endoribonucleases are thought to arrest growth of Mycobacterium tuberculosis by global translation inhibition. Here, Barth et al. show that MazF-mt9 cleaves a specific tRNA, leading to ribosome stalling at AAA codons and thus selective mRNA degr
Externí odkaz:
https://doaj.org/article/f04dbec7370047aab331fe63b011becb
Autor:
Irina O. Vvedenskaya, Bryce E. Nickels
Publikováno v:
STAR Protocols, Vol 1, Iss 1, Pp 100002- (2020)
Summary: Nucleoside-containing metabolites such as the oxidized and reduced forms of nicotinamide adenine dinucleotide (NAD+ and NADH), 3′-desphospho-coenzyme A (dpCoA), and flavin adenine dinucleotide (FAD) can be incorporated as RNA 5′ end caps
Externí odkaz:
https://doaj.org/article/c823356c0ac741ccbfb1893ea9978765
Transcription start site (TSS) selection is a key step in gene expression and occurs at many promoter positions over a wide range of efficiencies. Here, we develop a massively parallel reporter assay to quantitatively dissect contributions of promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d27fd0176aad542ba159e0dd29168e27
https://doi.org/10.1101/2021.11.09.467992
https://doi.org/10.1101/2021.11.09.467992
Autor:
Kathryn M Ramsey, Melisa L Osborne, Irina O Vvedenskaya, Cathy Su, Bryce E Nickels, Simon L Dove
Publikováno v:
PLoS Pathogens, Vol 11, Iss 4, p e1004793 (2015)
Francisella tularensis is a Gram-negative bacterium whose ability to replicate within macrophages and cause disease is strictly dependent upon the coordinate activities of three transcription regulators called MglA, SspA, and PigR. MglA and SspA form
Externí odkaz:
https://doaj.org/article/5cd4971f2c814ab0b8cae04fb6aa4ea0
Autor:
Kyle S, Skalenko, Lingting, Li, Yuanchao, Zhang, Irina O, Vvedenskaya, Jared T, Winkelman, Alexander L, Cope, Deanne M, Taylor, Premal, Shah, Richard H, Ebright, Justin B, Kinney, Yu, Zhang, Bryce E, Nickels
Publikováno v:
Proc Natl Acad Sci U S A
Chemical modifications of RNA 5′-ends enable “epitranscriptomic” regulation, influencing multiple aspects of RNA fate. In transcription initiation, a large inventory of substrates compete with nucleoside triphosphates for use as initiating enti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a83e90107ae3e84ab3625e339457735d
https://pubmed.ncbi.nlm.nih.gov/34187896
https://pubmed.ncbi.nlm.nih.gov/34187896
Autor:
Lingting Li, Yuanchao Zhang, Irina O. Vvedenskaya, Bryce E. Nickels, Deanne Taylor, Kyle S. Skalenko, Premal Shah, Yu Zhang, Richard H. Ebright, Jared T. Winkelman, Justin B. Kinney, Alexander L. Cope
Publikováno v:
Proceedings of the National Academy of Sciences. 118
Chemical modifications of RNA 5'-ends enable "epitranscriptomic" regulation, influencing multiple aspects of RNA fate. In transcription initiation, a large inventory of substrates compete with nucleoside triphosphates for use as initiating entities,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d673f5619b1c52f0f2ad2c28c4e13fec
https://doi.org/10.1073/pnas.2106388118
https://doi.org/10.1073/pnas.2106388118