Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Irina N. Marinova"'
Autor:
Ieva Bagdonaite, Irina N. Marinova, Asha M. Rudjord-Levann, Emil M. H. Pallesen, Sarah L. King-Smith, Richard Karlsson, Troels B. Rømer, Yen-Hsi Chen, Rebecca L. Miller, Sigvard Olofsson, Rickard Nordén, Tomas Bergström, Sally Dabelsteen, Hans H. Wandall
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Viral and host glycans represent an understudied aspect of host-pathogen interactions, despite potential implications for treatment of viral infections. This is due to lack of easily accessible tools for analyzing glycan function in a meanin
Externí odkaz:
https://doaj.org/article/80ea0c4849164c8d9697a64b5796ebff
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100668- (2021)
Summary: Glycosylation is one of the most common protein modifications in living organisms and has important regulatory roles in animal tissue development and homeostasis. Here, we present a protocol for generation of 3D organotypic skin models using
Externí odkaz:
https://doaj.org/article/fc8cfc673456492c9f0a28d065f3921c
Autor:
Noortje de Haan, Yoshiki Narimatsu, Mikkel Koed Møller Aasted, Ida S. B. Larsen, Irina N. Marinova, Sally Dabelsteen, Sergey Y. Vakhrushev, Hans H. Wandall
Publikováno v:
de Haan, N, Narimatsu, Y, Aasted, M K M, Larsen, I S B, Marinova, I N, Dabelsteen, S, Vakhrushev, S Y & Wandall, H H 2022, ' In-Depth Profiling of O-Glycan Isomers in Human Cells Using C18 Nanoliquid Chromatography-Mass Spectrometry and Glycogenomics ', Analytical Chemistry, vol. 94, no. 10, pp. 4343-4351 . https://doi.org/10.1021/acs.analchem.1c05068
O-Glycosylation is an omnipresent modification of the human proteome affecting many cellular functions, including protein cleavage, protein folding, and cellular signaling, interactions, and trafficking. The functions are governed by differentially r
Autor:
Zilu Ye, Gülcan Kilic, Sally Dabelsteen, Irina N. Marinova, Jens F. B. Thøfner, Ming Song, Asha M. Rudjord-Levann, Ieva Bagdonaite, Sergey Y. Vakhrushev, Cord H. Brakebusch, Jesper V. Olsen, Hans H. Wandall
Publikováno v:
Science Signaling. 15
Transforming growth factor–β (TGF-β) signaling regulates various aspects of cell growth and differentiation and is often dysregulated in human cancers. We combined genetic engineering of a human organotypic three-dimensional (3D) skin model with
Autor:
Ieva Bagdonaite, Irina N Marinova, Asha M Rudjord-Levann, Emil MH Pallesen, Sarah King-Smith, Troels B Rømer, Yen-Hsi Chen, Sigvard Olofsson, Rickard Nordén, Tomas Bergström, Sally Dabelsteen, Hans H Wandall
Viral and host glycans represent an understudied aspect of host-pathogen interactions, despite potential implications for treatment of viral infections. This is due to lack of easily accessible tools for analyzing glycan function in a meaningful cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c082028b7ff19126b81277989aeeafb
https://doi.org/10.1101/2022.10.23.513399
https://doi.org/10.1101/2022.10.23.513399
Autor:
Irina N Marinova, Jacob Engelbrecht, Adrian Ewald, Lasse L Langholm, Christian Holmberg, Birthe B Kragelund, Colin Gordon, Olaf Nielsen, Rasmus Hartmann-Petersen
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117779 (2015)
The protein called p97 in mammals and Cdc48 in budding and fission yeast is a homo-hexameric, ring-shaped, ubiquitin-dependent ATPase complex involved in a range of cellular functions, including protein degradation, vesicle fusion, DNA repair, and ce
Externí odkaz:
https://doaj.org/article/e1c3fa01655a45f6926fab2138ed01f3
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 3, Pp 100668-(2021)
Marinova, I N, Wandall, H H & Dabelsteen, S 2021, ' Protocol for CRISPR-Cas9 modification of glycosylation in 3D organotypic skin models ', STAR Protocols, vol. 2, no. 3, 100668 . https://doi.org/10.1016/j.xpro.2021.100668
STAR Protocols, Vol 2, Iss 3, Pp 100668-(2021)
Marinova, I N, Wandall, H H & Dabelsteen, S 2021, ' Protocol for CRISPR-Cas9 modification of glycosylation in 3D organotypic skin models ', STAR Protocols, vol. 2, no. 3, 100668 . https://doi.org/10.1016/j.xpro.2021.100668
Summary Glycosylation is one of the most common protein modifications in living organisms and has important regulatory roles in animal tissue development and homeostasis. Here, we present a protocol for generation of 3D organotypic skin models using
Autor:
Jesper V. Olsen, Cord Brakebusch, Ieva Bagdonaite, Sally Dabelsteen, Jens Frederik Bang Thøfner, Sergey Y. Vakhrushev, Hans H. Wandall, Irina N. Marinova, Zilu Ye, Asha M. Rudjord-Levann, Gülcan Kilic
Publikováno v:
SSRN Electronic Journal.
Transforming growth factor β (TGFβ) signaling is essential for cell growth and differentiation. Yet, the role of the individual TGFβ signaling components in human tissue homeostasis and transformation is still not completely understood. Here we ap
Autor:
Hans H. Wandall, Hiren J. Joshi, Ieva Bagdonaite, Eric P. Bennett, Stine F. Pedersen, Mathias I Nielsen, Irina N. Marinova, Sergey Y. Vakhrushev, Zilu Ye, Signe Hoejland Kramer, Sally Dabelsteen, Emil Mh Pallesen
Publikováno v:
EMBO reports
EMBO Reports
Bagdonaite, I, Pallesen, E M H, Ye, Z, Vakhrushev, S Y, Marinova, I N, Nielsen, M I, Kramer, S H, Pedersen, S F, Joshi, H J, Bennett, E P, Dabelsteen, S & Wandall, H H 2020, ' O-glycan initiation directs distinct biological pathways and controls epithelial differentiation ', EMBO Reports, vol. 21, no. 6, e48885 . https://doi.org/10.15252/embr.201948885
EMBO Reports
Bagdonaite, I, Pallesen, E M H, Ye, Z, Vakhrushev, S Y, Marinova, I N, Nielsen, M I, Kramer, S H, Pedersen, S F, Joshi, H J, Bennett, E P, Dabelsteen, S & Wandall, H H 2020, ' O-glycan initiation directs distinct biological pathways and controls epithelial differentiation ', EMBO Reports, vol. 21, no. 6, e48885 . https://doi.org/10.15252/embr.201948885
Post‐translational modifications (PTMs) greatly expand the function and potential for regulation of protein activity, and O‐glycosylation is among the most abundant and diverse PTMs. Initiation of O‐GalNAc glycosylation is regulated by 20 disti
Autor:
Asha M.R. Levann, David Thein Aagaard, Irina N. Marinova, Hans H. Wandall, Emil M.H. Pallesen, Sally Dabelsteen, Troels Boldt Rømer, Maria Adamopoulou, Mathias I Nielsen
Publikováno v:
Glycoconjugate Journal. 34:1-120