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of 47
pro vyhledávání: '"Irina Mikhailenko"'
Correction: LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages.
Autor:
Anna P Lillis, Selen Catania Muratoglu, Dianaly T Au, Mary Migliorini, Mi-Jeong Lee, Susan K Fried, Irina Mikhailenko, Dudley K Strickland
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147457 (2016)
Externí odkaz:
https://doaj.org/article/03c4d359873f48c88a6f24c5b9852c3c
Autor:
Anna P Lillis, Selen Catania Muratoglu, Dianaly T Au, Mary Migliorini, Mi-Jeong Lee, Susan K Fried, Irina Mikhailenko, Dudley K Strickland
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128903 (2015)
Within the circulation, cholesterol is transported by lipoprotein particles and is taken up by cells when these particles associate with cellular receptors. In macrophages, excessive lipoprotein particle uptake leads to foam cell formation, which is
Externí odkaz:
https://doaj.org/article/0c61b435f811431aaecea9e18437895e
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 10, Pp 1859-1869 (2003)
Inhibitors of the human immunodeficiency virus (HIV)-1 protease have proven to be effective antiretroviral drugs. However, patients receiving these drugs develop serious metabolic abnormalities, including hypercholesterolemia. The objective of the pr
Externí odkaz:
https://doaj.org/article/de3037d26dbe46d892ea1e4eb7deb4b6
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70432 (2013)
The PDGF signaling pathway plays a major role in several biological systems, including vascular remodeling that occurs following percutaneous transluminal coronary angioplasty. Recent studies have shown that the LDL receptor-related protein 1 (LRP1)
Externí odkaz:
https://doaj.org/article/c967ff9e9f3b4bee83f52f390951b92e
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19414 (2011)
Although endosomal compartments have been suggested to play a role in unconventional protein secretion, there is scarce experimental evidence for such involvement. Here we report that recycling endosomes are essential for externalization of cytoplasm
Externí odkaz:
https://doaj.org/article/ad5212c6594344929111761f4cee4378
Autor:
Dan Yu, Xiaoguo H Zhan, Shuqiong Niu, Irina Mikhailenko, Dudley K Strickland, Jianwei Zhu, Meng Cao, Xi Zhan
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20845 (2011)
Missing in metastasis (MIM) is a member of the inverse BAR-domain protein family, and in vitro studies have implied MIM plays a role in deforming membrane curvature into filopodia-like protrusions and cell dynamics. Yet, the physiological role of the
Externí odkaz:
https://doaj.org/article/b22d949bc84a45b8b3ba9645033c96cf
Autor:
Paul S. Blank, Adriana E. Golding, Ivonne Morales Benavides, Hang Waters, Elena Mekhedov, Ludmila Bezrukov, Rebecca D. Wachter, Irina Mikhailenko, Robert H. Brown, Carsten G. Bönnemann, Andrew P. Demidowich, Minal S. Jain, Jack A. Yanovski, Joshua Zimmerberg
STRUCTURED ABSTRACTBackground and ObjectivesMuscular dystrophies associated with decreased sarcolemma integrity lack validated clinical measures of sarcolemma fragility that can be used to assess disease progression and the effects of therapies desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b8224a439058b5d7f7cf4641f7153f4
https://doi.org/10.1101/2022.04.01.22273213
https://doi.org/10.1101/2022.04.01.22273213
Autor:
Paul S. Blank, Adriana E. Golding, Ivonne Morales Benavides, Hang Waters, Elena Mekhedov, Ludmila Bezrukov, Rebecca Wachter, Irina Mikhailenko, Robert H. Brown, Carsten Bonnemann, Andrew Demidowich, Mina Jain, Jack Yanovski, Joshua Zimmerberg
Publikováno v:
Biophysical Journal. 121:381a
Publikováno v:
Thrombosis and Haemostasis. 112:1244-1251
SummaryUpon conversion of fibrinogen into fibrin, fibrinogen αC-domains containing the RGD recognition motif form ordered αC polymers. Our previous study revealed that polymerisation of these domains promotes integrin-dependent adhesion and spreadi
Autor:
Irina Mikhailenko, Brian Hampton, Turhan Coksaygan, Selen C. Muratoglu, Dudley K. Strickland, Mary Migliorini, Shani Belgrave, Ling Chen
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:2137-2146
Objective— Low-density lipoprotein receptor–related protein 1 (LRP1) is a large endocytic and signaling receptor that is abundant in vascular smooth muscle cells. Mice in which the lrp1 gene is deleted in smooth muscle cells (smLRP1 −/− ) on