Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Irina Mazo"'
Autor:
Mauro Di Pilato, Yun Gao, Yi Sun, Amina Fu, Carina Grass, Thomas Seeholzer, Regina Feederle, Irina Mazo, Samuel W. Kazer, Kevin Litchfield, Ulrich H. von Andrian, Thorsten R. Mempel, Russell W. Jenkins, Daniel Krappmann, Peter Keller
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 6, Iss 2, Pp 61-73 (2023)
Introduction: Regulatory T cells (Tregs) play a critical role in the maintenance of immune homeostasis but also protect tumors from immune-mediated growth control or rejection and pose a significant barrier to effective immunotherapy. Inhibition of M
Externí odkaz:
https://doaj.org/article/dc5e74a62a884d328a611a253bea0c01
Autor:
Aude Thiriot, Carolina Perdomo, Guiying Cheng, Igor Novitzky-Basso, Sara McArdle, Jamie K. Kishimoto, Olga Barreiro, Irina Mazo, Robinson Triboulet, Klaus Ley, Antal Rot, Ulrich H. von Andrian
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-19 (2017)
Abstract Background Intravascular leukocyte recruitment in most vertebrate tissues is restricted to postcapillary and collecting venules, whereas capillaries and arterioles usually support little or no leukocyte adhesion. This segmental restriction i
Externí odkaz:
https://doaj.org/article/050129e035084436bbac9a72b2b37b96
Autor:
Peter Keller, Irina Mazo, Yun Gao, Vijayapal Reddy, Francisco Caballero, Sam Kazer, Dannah Miller, Roberto Gianani, James E. Marvin, Bret Stephens, Gregory L. Beatty, Ulrich H. von Andrian, Thorsten R. Mempel
Publikováno v:
Molecular Cancer Therapeutics. 20:P106-P106
Background Despite transforming effects of immune checkpoint blockade (ICB) therapy, objective response rates are low for most solid tumors. In the tumor microenvironment (TME), regulatory T cells are functionally unstable, likely due to changes in T
Autor:
Sarah Henrickson, Balimkiz Senman, Michael Quigley, Gabriela Alexe, Susanne Stutte, Jonathan Jesneck, Matteo Iannacone, Michael Flynn, Sabrina Imam, Irina Mazo, William Haining, Ulrich von Andrian
Publikováno v:
The Journal of Immunology. 188:110.21-110.21
Naïve CD8+ T cells are activated through interactions with antigen (Ag) bearing dendritic cells (DCs) in lymph nodes (LNs). Multiphoton intravital microscopy (MP-IVM) of LNs has demonstrated that T cell activation occurs in three phases. The durati