Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Irina M. Russu"'
Autor:
Irina M. Russu, Yuegao Huang
Publikováno v:
Biochemistry. 56(19)
Nuclear magnetic resonance spectroscopy and proton exchange are being used to characterize the opening reactions of individual base pairs in the RNA-DNA hybrid 5'-rGCGAUAAAAAGGCC-3'/5'-dGGCCTTTTTATCGC-3'. The hybrid contains a central tract of five r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0512aa1758f533d0d9bec7a537ba0228
https://pubmed.ncbi.nlm.nih.gov/28430414
https://pubmed.ncbi.nlm.nih.gov/28430414
Autor:
Alicia E. Every, Irina M. Russu
Publikováno v:
Journal of Molecular Recognition. 26:175-180
8-oxoguanine is a major lesion of genomic DNA that results from oxidation of guanine by reactive oxygen species. The repair of this lesion is initiated by 8-oxoguanine glycosylases, which excise the damaged base by “flipping” it outside the DNA d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::153a488da890013d7764bba922784dd5
https://doi.org/10.1002/jmr.2262
https://doi.org/10.1002/jmr.2262
Publikováno v:
Biochemistry. 48:3988-3997
Nuclear magnetic resonance spectroscopy and proton exchange have been used to characterize two RNA-DNA hybrids from the tR2 intrinsic transcription terminator site of phage lambda. The hybrids have the same base sequence [5'-GGCGCAGGCC(T/U)(T/U)CC-3'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8239fb62631c7b0ee3140a125cd276
https://doi.org/10.1021/bi900070f
https://doi.org/10.1021/bi900070f
Publikováno v:
Biochemistry. 45:13606-13613
The sarcin-ricin domain is a universal element of the RNA from the large ribosomal subunit. The domain is part of the binding site for elongation factors and is specifically cleaved by the toxins alpha-sarcin and ricin. In this work, we have mapped t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4977b563793f739b29044b9ac038713
https://doi.org/10.1021/bi060908n
https://doi.org/10.1021/bi060908n
Autor:
Irina M. Russu, Daniel Coman
Publikováno v:
Biophysical Journal. 89(5):3285-3292
The opening of basepairs plays a key role in DNA replication and transcription, and in the action of DNA repair and modification enzymes. In this article, we have used proton exchange to define the energetics of the pathways for basepair opening in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de5fcab2c123545396d2123eb4dc761
Autor:
Daniel Coman, Irina M. Russu
Publikováno v:
Journal of Biological Chemistry. 280:20216-20221
DNA-unwinding elements are specific base sequences that are located in the origin of DNA replication where they provide the start point for strand separation and unwinding of the DNA double helix. In the present work we have obtained the first charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf10b0fa4308a82a4400377b52bc450
https://doi.org/10.1074/jbc.m502773200
https://doi.org/10.1074/jbc.m502773200
Autor:
Daniel Coman, Irina M. Russu
Publikováno v:
Nucleic Acids Research. 32:878-883
Proton exchange and NMR spectroscopy have been used to define the effects of Mg2+ ions upon the stability of individual base pairs in the intramolecular parallel triple helix formed by the DNA oligonucleotide d(GAAGAGGTTTTTCCTCTTCTTTTTCTTCTCC). The r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5003bb5229dcc2ea4eb6bbaceebfa00
https://doi.org/10.1093/nar/gkh228
https://doi.org/10.1093/nar/gkh228
Allosteric effects of chloride ions at the intradimeric ?1?1 and ?2?2 interfaces of human hemoglobin
Autor:
Irina M. Russu, Iulian N. Rujan
Publikováno v:
Proteins: Structure, Function, and Genetics. 49:413-419
The structural transition induced by ligand binding in human hemoglobin encompasses quaternary structure changes at the interfaces between the two alphabeta dimers. In contrast, the interfaces between alpha and beta subunits within the same dimer (i.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d56f9eadc76c831f356e4ba8746675a
https://doi.org/10.1002/prot.10240
https://doi.org/10.1002/prot.10240
Autor:
Jie Zhang, Irina M. Russu
Publikováno v:
Biochemistry. 53(29)
The concatemer junction is a conserved sequence of 8 bp, which is strategically located at the junction between the head-to-tail repeats of genomic DNA in T7 and related bacteriophages. The RNA polymerase pauses at this site to recruit the machinery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfafca1799560c58af6abf4f818d62c
https://pubmed.ncbi.nlm.nih.gov/24998154
https://pubmed.ncbi.nlm.nih.gov/24998154
Publikováno v:
Proceedings of the National Academy of Sciences. 98:3773-3777
Allosteric effects in hemoglobin arise from the equilibrium between at least two energetic states of the molecule: a tense state, T, and a relaxed state, R. The two states differ from each other in the number and energy of the interactions between he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8071e8084d8829975bf666ec9ce3082a
https://doi.org/10.1073/pnas.071493598
https://doi.org/10.1073/pnas.071493598