Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Irina M. Larina"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Head-down bed rest (HDBR) is one of the models of the physiological effects of weightlessness used, among other things, to assess the effect of hypokinesia on the physiological systems of the human body and, first of all, on the cardiovascular system
Externí odkaz:
https://doaj.org/article/1c3d6fccc24c4fd1b8ae7f374099a59e
Autor:
Alexey S. Kononikhin, Natalia L. Starodubtseva, Alexander G. Brzhozovskiy, Alisa O. Tokareva, Daria N. Kashirina, Natalia V. Zakharova, Anna E. Bugrova, Maria I. Indeykina, Liudmila Kh. Pastushkova, Irina M. Larina, Vladimir A. Mitkevich, Alexander A. Makarov, Evgeny N. Nikolaev
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2403 (2024)
Background/Objectives: The development of blood tests for the early detection of individual predisposition to socially significant diseases remains a pressing issue. Methods: In this pilot study, multiple reaction monitoring mass spectrometry (MRM-MS
Externí odkaz:
https://doaj.org/article/2a40bf520acd4d018a20eac60e822063
Targeted MRM Quantification of Urinary Proteins in Chronic Kidney Disease Caused by Glomerulopathies
Autor:
Alexey S. Kononikhin, Alexander G. Brzhozovskiy, Anna E. Bugrova, Natalia V. Chebotareva, Natalia V. Zakharova, Savva Semenov, Anatoliy Vinogradov, Maria I. Indeykina, Sergey Moiseev, Irina M. Larina, Evgeny N. Nikolaev
Publikováno v:
Molecules, Vol 28, Iss 8, p 3323 (2023)
Glomerulopathies with nephrotic syndrome that are resistant to therapy often progress to end-stage chronic kidney disease (CKD) and require timely and accurate diagnosis. Targeted quantitative urine proteome analysis by mass spectrometry (MS) with mu
Externí odkaz:
https://doaj.org/article/446c2cb16b0c42fd8189dc9af1c12fdd
Autor:
Daria N. Kashirina, Alexander G. Brzhozovskiy, Wen Sun, Ludmila Kh. Pastushkova, Olga V. Popova, Vasiliy B. Rusanov, Evgeny N. Nikolaev, Irina M. Larina, Alexey S. Kononikhin
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/45379b11e100459692cb8a27b0ef604c
Autor:
Ludmila Kh. Pastushkova, Vasily B. Rusanov, Anna G. Goncharova, Andrei M. Nosovskiy, Elena S. Luchitskaya, Daria N. Kashirina, Alexey S. Kononikhin, Anna R. Kussmaul, Yusef D. Yakhya, Irina M. Larina, Evgeny N. Nikolaev
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The study presents the results of evaluating the changes in the concentrations of blood plasma proteins associated with heart rate variability (HRV) in cosmonauts who have completed space missions lasting about 6months. The concentrations of 125 prot
Externí odkaz:
https://doaj.org/article/030ce10721a24e0db15ebca94a93b42f
Autor:
Daria N. Kashirina, Andrew J. Percy, Liudmila Kh. Pastushkova, Christoph H. Borchers, Kirill S. Kireev, Vladimir A. Ivanisenko, Alexey S. Kononikhin, Eugene N. Nikolaev, Irina M. Larina
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S2, Pp 97-105 (2019)
Abstract Background The conditions of space flight have a significant effect on the physiological processes in the human body, yet the molecular mechanisms driving physiological changes remain unknown. Methods Blood samples of 18 Russian cosmonauts w
Externí odkaz:
https://doaj.org/article/6173c817aaaa433882aeb336d780aa31
Autor:
Vasily B. Rusanov, Ludmila Kh. Pastushkova, Irina M. Larina, Anna G. Chernikova, Anna G. Goncharova, Andrei M. Nosovsky, Daria N. Kashirina, Alexander G. Brzhozovsky, Nastassia Navasiolava, Alexey S. Kononikhin, Anna R. Kussmaul, Marc-Antoine Custaud, Evgeny N. Nikolaev
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The purpose of the study was to investigate the regulatory and metabolic changes in the circulatory system when simulating microgravity conditions in a five-day dry immersion. These changes reflect the adaptation processes characteristic for the init
Externí odkaz:
https://doaj.org/article/540387c5246749daaa6ea29a2c11bc2d
Autor:
Daria N. Kashirina, Alexander G. Brzhozovskiy, Ludmila Kh. Pastushkova, Alexey S. Kononikhin, Christoph H. Borchers, Evgeny N. Nikolaev, Irina M. Larina
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/3114f198a9dd4efe82e406c0bb512634
Autor:
Irina M. Larina, Andrew J. Percy, Juncong Yang, Christoph H. Borchers, Andrei M. Nosovsky, Anatoli I. Grigoriev, Evgeny N. Nikolaev
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract The effects of spaceflight on human physiology is an increasingly studied field, yet the molecular mechanisms driving physiological changes remain unknown. With that in mind, this study was performed to obtain a deeper understanding of chang
Externí odkaz:
https://doaj.org/article/f462ad54401c458f8b2253dd84b6c722
Autor:
Irina M. Larina, Irina V. Ogneva
Publikováno v:
International Journal of Biomedicine, Vol 4, Iss 3, Pp 129-137 (2014)
The review aims to analyze the relationship between metabolic changes in muscle tissue occurring in space flight conditions and other body systems during the developing atrophy. The data about the activity of various enzyme systems in muscles, liver
Externí odkaz:
https://doaj.org/article/71e509d19c3042ea952f436ffad047af