Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Irina Kiprianova"'
Autor:
Irina Kiprianova, Janina Remy, Nelli Milosch, Isabelle V. Mohrenz, Volker Seifert, Achim Aigner, Donat Kögel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 7, Pp 564-573 (2015)
The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3) is overactivated in malignant glioma and plays a key role in promoting cell survival, thereby increasing the acquired apoptosis resistance of these tumors.
Externí odkaz:
https://doaj.org/article/422273b6d3394659a937774385f82e3b
Autor:
Bernard Huber, Andreas Unterberg, Volker Daniel, Jeremy Fry, Rauf Bhat, Jan Oliver Neumann, Elena Terletskaia-Ladwig, Birgit Beelte, Jean Rommelaere, Jacek Hajda, Karin Jochims, Alexandra Just, Irina Kiprianova, Assia L. Angelova, Stephanie Löbhard, Karsten Geletneky, Barbara Leuchs, Johannes Hüsing, Andreas von Deimling, Tilman Schöning, Wolfgang Brück, David Capper, Veronika Frehtman, Andreas J. Bartsch, Ottheinz Krebs, Mandy Roscher, Michael Dahm
Publikováno v:
Molecular Therapy
Oncolytic virotherapy may be a means of improving the dismal prognosis of malignant brain tumors. The rat H-1 parvovirus (H-1PV) suppresses tumors in preclinical glioma models, through both direct oncolysis and stimulation of anticancer immune respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1034b042276f003f0a7d751056481f93
http://europepmc.org/articles/PMC5768665
http://europepmc.org/articles/PMC5768665
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2058
Fluorescence in situ hybridization (FISH) is a specific, sensitive, accurate, and reliable technique widely applied in both research and clinic. Here we describe the detailed protocol of a FISH method established by us to serve the scientific purpose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b2dd2f9981376a0961b1edf1fc7f269
https://pubmed.ncbi.nlm.nih.gov/31486047
https://pubmed.ncbi.nlm.nih.gov/31486047
Publikováno v:
Methods in Molecular Biology ISBN: 9781493997930
Fluorescence in situ hybridization (FISH) is a specific, sensitive, accurate, and reliable technique widely applied in both research and clinic. Here we describe the detailed protocol of a FISH method established by us to serve the scientific purpose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae5a6a1b835864506f67c92c18614035
https://doi.org/10.1007/978-1-4939-9794-7_20
https://doi.org/10.1007/978-1-4939-9794-7_20
Publikováno v:
Current Opinion in Virology. 13:17-24
The H-1 parvovirus (H-1PV) exerts oncosuppressive action that has two components: oncotoxicity and immunostimulation. While many human tumor cells, including conventional drug-resistant ones, can be killed by H-1PV, some fail to support progeny virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437d309796b79cfc6a299910f9da84fc
https://doi.org/10.1016/j.coviro.2015.03.008
https://doi.org/10.1016/j.coviro.2015.03.008
Autor:
Irina Kiprianova, Ali Ayache, Michele Klein, Nadja Thomas, Barbara Leuchs, Manuel Fischer, Joerg R. Schlehofer, Jean Rommelaere
Publikováno v:
Clinical Cancer Research. 17:5333-5342
Purpose: In previous studies, we have shown that the apathogenic rat parvovirus H-1 (H-1PV) is capable to induce regression of advanced symptomatic rat and human gliomas in a rat model, when the virus was injected in the tumor (intracranially) or int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0877b6af52410be27b641d7a60d336fa
https://doi.org/10.1158/1078-0432.ccr-10-3124
https://doi.org/10.1158/1078-0432.ccr-10-3124
Autor:
Irina Kiprianova, Jean Rommelaere, Ali Ayache, Nadja Thomas, Clemens Sommer, R. M. Koch, Marta Herrero y Calle, Karsten Geletneky, Jörg R. Schlehofer, Laurent Deleu
Publikováno v:
Neuro-Oncology. 12:804-814
Oncolytic virotherapy is a potential treatment modality under investigation for various malignancies including malignant brain tumors. Unlike some other natural or modified viruses that show oncolytic activity against cerebral neoplasms, the rodent p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7549c34da2e5dfe992b1a0b7692d8e62
https://doi.org/10.1093/neuonc/noq023
https://doi.org/10.1093/neuonc/noq023
Autor:
Irina Kiprianova, Klaus Unsicker, Andreas Schober, J. Jarosik, O. von Bohlen und Halbach, Sabrina Zechel
Publikováno v:
European Journal of Neuroscience. 23:1671-1675
Fibroblast growth factor 2 (FGF-2) was the first growth factor discovered that exerted prominent protective and regenerative effects in an animal model of Parkinson's disease, the MPTP-lesioned dopaminergic nigrostriatal system. To address the putati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76356ea8d7cac045c40db6eb6ae34b10
https://doi.org/10.1111/j.1460-9568.2006.04700.x
https://doi.org/10.1111/j.1460-9568.2006.04700.x
Publikováno v:
Experimental Neurology. 159:511-519
We investigated the effect of brain-derived neurotrophic factor (BDNF) on hippocampal long-term potentiation (LTP) and cognitive functions after global cerebral ischemia in the rat. After four-vessel occlusion, BDNF was administered via an osmotic mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afbd0eefb79a1f38ed5efff72dcc81d
https://doi.org/10.1006/exnr.1999.7109
https://doi.org/10.1006/exnr.1999.7109
Autor:
Matthias Spranger, Stefan Schwab, Irina Kiprianova, Stephanie Desiderato, Roland Galmbacher, Thomas M. Freiman, Frank Gillardon
Publikováno v:
Journal of Neuroscience Research. 56:21-27
The expression of brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase B are both increased after global ischemia. Therefore, a protective action of BDNF against the delayed degeneration of vulnerable neurons has been suggested.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3b4103b0497df9f17f34e3f7f72008
https://doi.org/10.1002/(sici)1097-4547(19990401)56:1<21::aid-jnr3>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19990401)56:1<21::aid-jnr3>3.0.co