Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Irina Gulerez"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract The phosphatases of regenerating liver (PRLs) are involved in tumorigenesis and metastatic cancer yet their cellular function remains unclear. Recent reports have shown PRL phosphatases bind tightly to the CNNM family of membrane proteins to
Externí odkaz:
https://doaj.org/article/0fb93675d99f4329802dc664671cbeb7
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-1 (2017)
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper
Externí odkaz:
https://doaj.org/article/447c938499dd41cd8e9f8da85f7b9141
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
The phosphatases of regenerating liver (PRLs) are involved in tumorigenesis and metastatic cancer yet their cellular function remains unclear. Recent reports have shown PRL phosphatases bind tightly to the CNNM family of membrane proteins to regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71624a2852b711e5ee07a835e1101bba
https://doaj.org/article/0fb93675d99f4329802dc664671cbeb7
https://doaj.org/article/0fb93675d99f4329802dc664671cbeb7
Autor:
Kalle Gehring, Irina Gulerez
Publikováno v:
Methods. 65:175-183
Protein tyrosine phosphatases (PTPs) are well recognized as key targets in a wide spectrum of diseases, such as diabetes, obesity and cancer. Their roles in these maladies have been successfully characterized by various methods. However, it is only b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb35186905dba5d90e98f9878ffa078
https://doi.org/10.1016/j.ymeth.2013.07.032
https://doi.org/10.1016/j.ymeth.2013.07.032
Autor:
Hiroaki Miki, Howie Wu, Meng Yang, Yosuke Funato, Kalle Gehring, Guennadi Kozlov, Irina Gulerez
PRLs (phosphatases of regenerating liver) are frequently overexpressed in human cancers and are prognostic markers of poor survival. Despite their potential as therapeutic targets, their mechanism of action is not understood in part due to their weak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0d228e90a5341d2d118fa2e9a9a796
https://europepmc.org/articles/PMC5283600/
https://europepmc.org/articles/PMC5283600/
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 73:C233-C233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5876d49c7b9d4094569c7dada056a894
https://doi.org/10.1107/s2053273317093408
https://doi.org/10.1107/s2053273317093408
Protein disulfide isomerases are responsible for catalyzing the proper oxidation and isomerization of disulfide bonds of newly synthesized proteins in the endoplasmic reticulum. Here, the crystal structure of the third catalytic domain of protein dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a82fbf88ec3984db613a71ad6723cb
https://europepmc.org/articles/PMC3325802/
https://europepmc.org/articles/PMC3325802/
Autor:
Kalle Gehring, Irina Gulerez
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 70:C810-C810
The Phosphatase of Regenerating Liver (PRL) family, a subgroup of the protein tyrosine phosphatases, comprises three highly oncogenic members, PRL-1, -2 and -3, implicated in the progression of numerous cancer types. PRL-2 is overexpressed in breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::835a24266867ffebf156067e29522336
https://doi.org/10.1107/s205327331409189x
https://doi.org/10.1107/s205327331409189x