Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Irina Gromova"'
Autor:
Thilde Terkelsen, Maria Pernemalm, Pavel Gromov, Anna‐Lise Børresen‐Dale, Anders Krogh, Vilde D. Haakensen, Janne Lethiö, Elena Papaleo, Irina Gromova
Publikováno v:
Molecular Oncology, Vol 15, Iss 2, Pp 429-461 (2021)
Despite significant advancements in breast cancer (BC) research, clinicians lack robust serological protein markers for accurate diagnostics and tumor stratification. Tumor interstitial fluid (TIF) accumulates aberrantly externalized proteins within
Externí odkaz:
https://doaj.org/article/881a2b44cdee49d6b366c7cff30ef480
Autor:
Thilde Terkelsen, Francesco Russo, Pavel Gromov, Vilde Drageset Haakensen, Søren Brunak, Irina Gromova, Anders Krogh, Elena Papaleo
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-36 (2020)
Abstract Background Studies on tumor-secreted microRNAs point to a functional role of these in cellular communication and reprogramming of the tumor microenvironment. Uptake of tumor-secreted microRNAs by neighboring cells may result in the silencing
Externí odkaz:
https://doaj.org/article/1ed099dfd9024ac990537c391fee6e81
Autor:
Cinzia Tesauro, Anne Katrine Simonsen, Marie Bech Andersen, Kamilla Wandsoe Petersen, Emil Laust Kristoffersen, Line Algreen, Noriko Yokoyama Hansen, Anne Bech Andersen, Ann Katrine Jakobsen, Magnus Stougaard, Pavel Gromov, Birgitta R. Knudsen, Irina Gromova
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)
Abstract Background Camptothecin (CPT) and its derivatives are currently used as second- or third-line treatment for patients with endocrine-resistant breast cancer (BC). These drugs convert nuclear enzyme DNA topoisomerase I (TOP1) to a cell poison
Externí odkaz:
https://doaj.org/article/5bdd00634203464bab2f0dbccd74d249
Autor:
Thilde Terkelsen, Vilde D. Haakensen, Radka Saldova, Pavel Gromov, Merete Kjær Hansen, Henning Stöckmann, Ole Christian Lingjærde, Anne‐Lise Børresen‐Dale, Elena Papaleo, Åslaug Helland, Pauline M. Rudd, Irina Gromova
Publikováno v:
Molecular Oncology, Vol 12, Iss 6, Pp 972-990 (2018)
Particular N‐glycan structures are known to be associated with breast malignancies by coordinating various regulatory events within the tumor and corresponding microenvironment, thus implying that N‐glycan patterns may be used for cancer stratifi
Externí odkaz:
https://doaj.org/article/5b23a44b783c46a592759e58956d4150
Autor:
Irina Gromova, Jaime A. Espinoza, Morten Grauslund, Eric Santoni-Rugiu, Maj-Lis Møller Talman, Jan van Oostrum, José M. A. Moreira
Publikováno v:
Cells, Vol 10, Iss 10, p 2768 (2021)
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that comprises various disease entities, all of which share a set of common features: a lack of expression of the estrogen receptor, progesterone receptor, and human epidermal growth
Externí odkaz:
https://doaj.org/article/3a60e3eeae554b71aff398ad6400e135
Autor:
Shakila Jabeen, Jaime A. Espinoza, Lilly Anne Torland, Manuela Zucknick, Surendra Kumar, Vilde D. Haakensen, Torben Lüders, Olav Engebraaten, Anne-Lise Børresen-Dale, Jon Amund Kyte, Pavel Gromov, Bjørn Naume, Vessela Kristensen, Irina Gromova, Xavier Tekpli
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Cancers elicit an immune response by modifying the microenvironment. The immune system plays a pivotal role in cancer recognition and eradication. While the potential clinical value of infiltrating lymphocytes at the tumor site has been assessed in b
Externí odkaz:
https://doaj.org/article/916d29b9b703470980e669bea57b6e3e
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188827 (2017)
Bladder cancer associated protein (Blcap) expression is commonly down-regulated in invasive bladder cancer, and may have prognostic value given that its expression is negatively correlated with patient survival. We have previously investigated the ex
Externí odkaz:
https://doaj.org/article/9fd81b163719459cbdb4f51868d48d01
Autor:
Yi Chieh Lim, Kamilla E Jensen, Diana Aguilar-Morante, Lina Vardouli, Kristoffer Vitting-Seerup, Ryan C Gimple, Qiulian Wu, Henriette Pedersen, Kirstine J Elbaek, Irina Gromova, Robert Ihnatko, Bjarne W Kristensen, Jeanette K Petersen, Jane Skjoth-Rasmussen, William Flavahan, Jeremy N Rich, Petra Hamerlik
Publikováno v:
Neuro Oncol
Background Glioblastoma (GBM) is a highly lethal malignancy for which neoangiogenesis serves as a defining hallmark. The anti-VEGF antibody, bevacizumab, has been approved for the treatment of recurrent GBM, but resistance is universal. Methods We an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71abd4767dc3df913116d34dcacad495
https://europepmc.org/articles/PMC9925708/
https://europepmc.org/articles/PMC9925708/
Autor:
Pavel Gromov, Jaime A Espinoza, Maj-Lis Talman, Naoko Honma, Niels Kroman, Vera Timmermans Wielenga, José M A Moreira, Irina Gromova
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112024 (2014)
Apocrine carcinoma of the breast is a distinctive malignancy with unique morphological and molecular features, generally characterized by being negative for estrogen and progesterone receptors, and thus not electable for endocrine therapy. Despite th
Externí odkaz:
https://doaj.org/article/a5c16ab460534797982bc767c14fec5b
Autor:
Amit Roy, Cinzia Tesauro, Rikke Frøhlich, Marianne S Hede, Maria J Nielsen, Eigil Kjeldsen, Bjarne Bonven, Magnus Stougaard, Irina Gromova, Birgitta R Knudsen
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99628 (2014)
The CD44+ and CD44- subpopulations of the colorectal cancer cell line Caco2 were analyzed separately for their sensitivities to the antitumor drug camptothecin. CD44+ cells were less sensitive to camptothecin than CD44- cells. The relative resistance
Externí odkaz:
https://doaj.org/article/766ddafd11cc4af1bc4fb673e4fd74c0