Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Irina Gazaryan"'
Autor:
Priyanka Soni, Navneet Ammal Kaidery, Sudarshana M. Sharma, Irina Gazaryan, Sergey V. Nikulin, Dmitry M. Hushpulian, Bobby Thomas
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Neurodegenerative diseases represent a pressing global health challenge, and the identification of novel mechanisms underlying their pathogenesis is of utmost importance. Ferroptosis, a non-apoptotic form of regulated cell death characterized by iron
Externí odkaz:
https://doaj.org/article/f038aea9e6284c14be3570e61d8fc184
Autor:
Bashayer R. Al-Mubarak, Karen F.S. Bell, Sudhir Chowdhry, Paul J. Meakin, Paul S. Baxter, Sean McKay, Owen Dando, Michael L.J. Ashford, Irina Gazaryan, John D. Hayes, Giles E. Hardingham
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102158- (2021)
The transcription factor Nrf2 is a stress-responsive master regulator of antioxidant, detoxification and proteostasis genes. In astrocytes, Nrf2-dependent gene expression drives cell-autonomous cytoprotection and also non-cell-autonomous protection o
Externí odkaz:
https://doaj.org/article/bfac644fbd9a4a15bd392002c220b8e0
Autor:
Amit Kumar, Manisha Vaish, Saravanan S Karuppagounder, Irina Gazaryan, John W Cave, Anatoly A Starkov, Elizabeth T Anderson, Sheng Zhang, John T Pinto, Austin M Rountree, Wang Wang, Ian R Sweet, Rajiv R Ratan
Publikováno v:
eLife, Vol 10 (2021)
Hypoxic adaptation mediated by HIF transcription factors requires mitochondria, which have been implicated in regulating HIF1α stability in hypoxia by distinct models that involve consuming oxygen or alternatively converting oxygen into the second m
Externí odkaz:
https://doaj.org/article/5101dfdcd63d48c8a22c4fac2e9e0afc
Autor:
Manuj Ahuja, Navneet Ammal Kaidery, Debashis Dutta, Otis C. Attucks, Eliot H. Kazakov, Irina Gazaryan, Mitsuyo Matsumoto, Kazuhiko Igarashi, Sudarshana M. Sharma, Bobby Thomas
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1780 (2022)
Parkinson’s disease (PD) is the second most common neurodegenerative movement disorder characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Although a complex interplay of multiple environmental and gen
Externí odkaz:
https://doaj.org/article/826cc5ab347d47988b76837e6681c0a4
Autor:
Alexander Popov, Anna Klimovich, Olga Styshova, Alexander Tsybulsky, Dmitry Hushpulian, Andrey Osipyants, Anna Khristichenko, Sergey Kazakov, Manuj Ahuja, Navneet Kaidery, Bobby Thomas, Vladimir Tishkov, Abraham Brown, Irina Gazaryan, Andrey Poloznikov
Publikováno v:
Molecules, Vol 27, Iss 3, p 628 (2022)
Ginsenoside Rh2 increases the efficacy of doxorubicin (DOX) treatment in murine models of solid and ascites Ehrlich’s adenocarcinoma. In a solid tumor model (treatment commencing 7 days after inoculation), DOX + Rh2 co-treatment was significantly m
Externí odkaz:
https://doaj.org/article/aa96fba63619447ab281733614675624
Autor:
Maria Savyuk, Mikhail Krivonosov, Tatiana Mishchenko, Irina Gazaryan, Mikhail Ivanchenko, Anna Khristichenko, Andrey Poloznikov, Dmitry Hushpulian, Sergey Nikulin, Evgeny Tonevitsky, Guzal Abuzarova, Elena Mitroshina, Maria Vedunova
Publikováno v:
Antioxidants, Vol 9, Iss 8, p 662 (2020)
A novel potent analog of the branched tail oxyquinoline group of hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitors, neuradapt, has been studied in two treatment regimes in an in vitro hypoxia model on murine primary hippocampal cultures. N
Externí odkaz:
https://doaj.org/article/190a771ad2484064962acf84212f51a6
Autor:
Kit-Kay Mak, Zhang Shiming, Ola Epemolu, Albena Dinkova-Kostova, Geoffrey Wells, Irina Gazaryan, Raghavendra Sakirolla, Zulkefeli Mohd, Mallikarjuna Rao Pichika
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76417fba8437ce74ac042c79f0f7a102
https://doi.org/10.2139/ssrn.4097876
https://doi.org/10.2139/ssrn.4097876
Autor:
Paul Baxter, Paul J. Meakin, John D. Hayes, Sudhir Chowdhry, Irina Gazaryan, Owen Dando, Giles E. Hardingham, Michael L.J. Ashford, Karen F.S. Bell, Sean McKay, Bashayer Al-Mubarak
Publikováno v:
Al-Mubarak, B, Bell, K, Chowdhry, S, Meakin, P J, Baxter, P, Mckay, S, Dando, O, Ashford, M L J, Gazaryan, I, Hayes, J D & Hardingham, G E 2021, ' Non-canonical Keap1-independent activation of Nrf2 in astrocytes by mild oxidative stress ', Redox biology . https://doi.org/10.1016/j.redox.2021.102158
Redox Biology, Vol 47, Iss, Pp 102158-(2021)
Redox Biology
Redox Biology, Vol 47, Iss, Pp 102158-(2021)
Redox Biology
The transcription factor Nrf2 is a stress-responsive master regulator of antioxidant, detoxification and proteostasis genes. In astrocytes, Nrf2-dependent gene expression drives cell-autonomous cytoprotection and also non-cell-autonomous protection o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667bc3004cb3513c3802be1a21560f42
https://hdl.handle.net/20.500.11820/4131380c-cf23-4e17-bd95-0adb0385adbb
https://hdl.handle.net/20.500.11820/4131380c-cf23-4e17-bd95-0adb0385adbb
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
Wild-type recombinant horseradish peroxidase purified and refolded from Escherichia coli inclusion bodies has been studied in the system of bis(2-ethylhexyl)sulphosuccinate sodium salt (Aerosol OT)-reversed micelles in octane. In contrast with native
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52de0023a0f8a4a414f12e7a56349b8
https://doi.org/10.1042/bj3280643
https://doi.org/10.1042/bj3280643
Publikováno v:
Journal of Physical Chemistry B; Feb2008, Vol. 112 Issue 7, p2233-2244, 12p