Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Irina G. Rybalkina"'
Autor:
Alexander M. Firsov, Sergei D. Rybalkin, Elena A. Kotova, Tatyana I. Rokitskaya, Yuri N. Antonenko, Irina G. Rybalkina
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1859:e113
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65ddae59be5dd8f07653a8f98c60773e
https://doi.org/10.1016/j.bbabio.2018.09.333
https://doi.org/10.1016/j.bbabio.2018.09.333
Publikováno v:
Molecular Pharmacology. 77:670-677
cGMP-specific phosphodiesterase (PDE5) has become a target for drug development for the treatment of a number of physiological dysfunctions, affected by changes in the cGMP/cGMP-dependent protein kinase (PKG) signaling pathway. PDE5 has two highly ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06ce8ec6fc19c580733a4823e527043
https://doi.org/10.1124/mol.109.062299
https://doi.org/10.1124/mol.109.062299
Autor:
Robert Feil, Wiebke Wolfsgruber, Sergei D. Rybalkin, Franz Hofmann, Joseph A. Beavo, Irina G. Rybalkina, Masami Shimizu-Albergine
Publikováno v:
The Journal of Neuroscience. 23:6452-6459
The nitric oxide (NO)-cGMP pathway has been implicated as playing a crucial role in the induction of cerebellar long-term depression (LTD). The amplitude and duration of the cGMP signal is controlled by cyclic nucleotide phosphodiesterases (PDEs). He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9ef277487019c125fc13082e20ef6e
https://doi.org/10.1523/jneurosci.23-16-06452.2003
https://doi.org/10.1523/jneurosci.23-16-06452.2003
Autor:
Xiao Bo Tang, Masami Shimizu-Albergine, Irina G. Rybalkina, Sergei D. Rybalkin, Joseph A. Beavo
Publikováno v:
The EMBO Journal. 22:469-478
cGMP-specific, cGMP-binding phosphodiesterase (PDE5) regulates such physiological processes as smooth muscle relaxation and neuronal survival. PDE5 contains two N-terminal domains (GAF A and GAF B), but the functional roles of these domains have not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00faa01f21787852ae60c552d7cbf8c7
https://doi.org/10.1093/emboj/cdg051
https://doi.org/10.1093/emboj/cdg051
Autor:
Karin E. Bornfeldt, Irina G. Rybalkina, Sergei D. Rybalkin, William K. Sonnenburg, Kim Hanson, Edwin G. Krebs, Joseph A. Beavo, Keith S. Kwak
Publikováno v:
Journal of Clinical Investigation. 100:2611-2621
The diversity among cyclic nucleotide phosphodiesterases provides multiple mechanisms for regulation of cAMP and cGMP in the cardiovascular system. Here we report that a calmodulin-stimulated phosphodiesterase (PDE1C) is highly expressed in prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755c49bdf150320e20aa0a8276e2f7f9
https://doi.org/10.1172/jci119805
https://doi.org/10.1172/jci119805
Publikováno v:
BMC Pharmacology. 7
Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99596c1ed0b095057fc8a6250b5df5cc
https://doi.org/10.1186/1471-2210-7-s1-s29
https://doi.org/10.1186/1471-2210-7-s1-s29
Publikováno v:
Circulation research. 90(2)
Proliferation of arterial smooth muscle cells (SMCs) is a key event in the formation of advanced atherosclerotic lesions and restenosis after angioplasty. Cyclic nucleotides (cAMP and cGMP) inhibit arterial SMC proliferation, and elevation of cyclic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38fa2af340f5e20100618639e742bc38
https://pubmed.ncbi.nlm.nih.gov/11834707
https://pubmed.ncbi.nlm.nih.gov/11834707
Publikováno v:
BMC Pharmacology
Background Calpain, intracellular non-lysosomal calcium-dependent proteinase, is activated by a number of signaling pathways that lead to the elevation of intraplatelet calcium concentrations. Physiological roles of calpain, highly expressed in plate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3190cbe4e6fa5ac82dbf45963075fe87
Autor:
Sergei D. Rybalkin, Kenneth L. Bible, Lawrence P. Wennogle, Stanley C. Froehner, Elina Minami, Masami Shimizu, Irina G. Rybalkina, Jennifer O'Brien, Franz Hofmann, Enrico Patrucco, Joseph A. Beavo
Publikováno v:
BMC Pharmacology & Toxicology
Background Duchenne muscular dystrophy (DMD) is the most common inherited form of muscular dystrophy, which results in skeletal muscle weakness by age 6. In its later stages DMD leads to dilated cardiomyopathy and heart failure with high level of mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fd4f13a7941ce69ac2e9d1688f9417