Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Irina Fonseca"'
Autor:
Irina Fonseca, Cíntia Horta, Ana Sofia Ribeiro, Barbara Sousa, Gaëlle Marteil, Mónica Bettencourt-Dias, Joana Paredes
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-12 (2023)
Abstract Polo-like kinase 4 (Plk4), the major regulator of centriole biogenesis, has emerged as a putative therapeutic target in cancer due to its abnormal expression in human carcinomas, leading to centrosome number deregulation, mitotic defects and
Externí odkaz:
https://doaj.org/article/0219254cd3364235a1c703b0b1589e7c
Autor:
Gaëlle Marteil, Adan Guerrero, André F. Vieira, Bernardo P. de Almeida, Pedro Machado, Susana Mendonça, Marta Mesquita, Beth Villarreal, Irina Fonseca, Maria E. Francia, Katharina Dores, Nuno P. Martins, Swadhin C. Jana, Erin M. Tranfield, Nuno L. Barbosa-Morais, Joana Paredes, David Pellman, Susana A. Godinho, Mónica Bettencourt-Dias
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Cancer cells are characterised by abnormalities in the number of centrosomes and this phenotype is linked with tumorigenesis. Here the authors report centriole length deregulation in a subset of cancer cell lines and suggest a link with subsequent al
Externí odkaz:
https://doaj.org/article/a9b31e151bf34283b9c2a8077242da36
Autor:
Irina Fonseca, Cíntia Horta, Ana Sofia Ribeiro, Barbara Sousa, Gaëlle Marteil, Mónica Bettencourt-Dias, Joana Paredes
Polo-like kinase 4 (Plk4), the major regulator of centriole biogenesis, has emerged as a putative therapeutic target in cancer due to its abnormal expression in human carcinomas, leading to centrosome number deregulation, mitotic defects and chromoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c461bae308b60b4bb8bf4b6c9ee5a8c9
https://doi.org/10.1101/2022.12.16.520613
https://doi.org/10.1101/2022.12.16.520613
