Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Irina Fernandez Curbelo"'
Autor:
Padmanee Sharma, James P. Allison, Ignacio I. Wistuba, Anirban Maitra, Shalini S. Yadav, Hao Zhao, Maria G. Higa, Jorge B. Scutti, Sumit K. Subudhi, Javier Chaparro-Riggers, Tao Sai, Edward Pascua, Terrence Park, John C. Lin, Ashley E. Mahne, Bevin M. Smith, Jorge Blando, Irina Fernandez Curbelo, Samantha L. Bucktrout, Luis Vence
Purpose:Determine the differential effect of a FcγR-binding, mIgG2a anti-GITR antibody in mouse tumor models, and characterize the tumor microenvironment for the frequency of GITR expression in T-cell subsets from seven different human solid tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160c22ead2ef40e11c9765bc9c16d2a9
https://doi.org/10.1158/1078-0432.c.6527769.v1
https://doi.org/10.1158/1078-0432.c.6527769.v1
Autor:
Catalin Mihalcioiu, Charlotte E. Ariyan, Michael K. Wong, Aurélie Fluckiger, Julie M. Simon, Rossanna C. Pezo, Michael G. White, Padmanee Sharma, Michael A. Postow, Sapna Pradyuman Patel, Adi Diab, Isabella C. Glitza, Elizabeth M. Burton, Whijae Roh, Zachary A. Cooper, Laurence Zitvogel, Maria Paula Roberti, Wen-Jen Hwu, Alexandria P. Cogdill, Miles C. Andrews, Gladys Ferrere, Abdul Wadud Khan, Scott E. Woodman, Robert R. Jenq, Christine N. Spencer, James P. Allison, Lisa Derosa, Curtis Gumbs, Wei Shen Chen, Stephanie S. Watowich, Irina Fernandez Curbelo, Michael A. Davies, Paule Opolon, Connie P.M. Duong, Jennifer A. Wargo, Maryam Tidjani Alou, Courtney W. Hudgens, Vancheswaran Gopalakrishnan, Pierre Olivier Gaudreau, Michael T. Tetzlaff, Didier Raoult, Arielle Elkrief, Khalida Wani, Jeffrey E. Gershenwald, Margaret K. Callahan, Sarah B. Johnson, Alexandre Reuben, Joseph F. Petrosino, Latasha Little, Peter A. Prieto, Matthew Lastrapes, Valerio Iebba, Bertrand Routy, Matthew Adamow, Alexander J. Lazar, Jennifer L. McQuade, Nadim J. Ajami, Golnaz Morad, Rodabe N. Amaria, Matthew C. Wong, Erez N. Baruch, Hussein Abdul-Hassan Tawbi, Satoru Yonekura, Li Zhao, Reetakshi Arora, Luis M Vence, Lauren E. Haydu, Luigi Nezi, Patrick Hwu, P. Andrew Futreal, Jianhua Zhang
Publikováno v:
Nature Medicine
Nature Medicine, 2021, 27 (8), pp.1432-1441. ⟨10.1038/s41591-021-01406-6⟩
Nature Medicine, Nature Publishing Group, 2021, 27 (8), pp.1432-1441. ⟨10.1038/s41591-021-01406-6⟩
Nature Medicine, 2021, 27 (8), pp.1432-1441. ⟨10.1038/s41591-021-01406-6⟩
Nature Medicine, Nature Publishing Group, 2021, 27 (8), pp.1432-1441. ⟨10.1038/s41591-021-01406-6⟩
International audience; Treatment with combined immune checkpoint blockade (CICB) targeting CTLA-4 and PD-1 is associated with clinical benefit across tumor types, but also a high rate of immune-related adverse events. Insights into biomarkers and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b68bdb823308a5d01ebdad2aabf30e
https://hal-amu.archives-ouvertes.fr/hal-03333724/file/2f0091ab-846d-4b59-9960-dcea2f6edc58.pdf
https://hal-amu.archives-ouvertes.fr/hal-03333724/file/2f0091ab-846d-4b59-9960-dcea2f6edc58.pdf
Autor:
Jennifer Wargo, Miles Andrews, Connie Duong, Vancheswaran Gopalakrishnan, Valerio Iebba, Wei-Shen Chen, Lisa Derosa, Bertrand Routy, Gladys Ferrere, Aurélie Fluckiger, Maria Roberti, Paule Opolon, Whijae Roh, Christine Spencer, Irina Fernandez Curbelo, Luis Vence, Alexandre Reuben, Zachary Cooper, Peter Prieto, M. A. Wadud Khan, Alexander Lazar, Michael Tetzlaff, Courtney Hudgens, Pierre-Olivier Gaudreau, Luigi Nezi, Didier Raoult, Lauren Haydu, Hussein Tawbi, Patrick Hwu, Wen-Jen Hwu, Rodabe Amaria, Elizabeth Burton, Scott Woodman, Adi Diab, Sapna Patel, Isabella Glitza, Jianhua Zhang, Nadim Ajami, Joseph Petrosino, Robert Jenq, Michael Davies, Jeffrey Gershenwald, Padmanee Sharma, James Allison, Andrew Futreal, Laurence Zitvogel, Maryam TIDJANI ALOU, Satoru Yonekura, Alexandria Cogdill, Reetakshi Arora, Latasha Little, Curtis Gumbs, Khalida Wani, Margaret Callahan, Mathew Adamow, Michael Postow, Charlotte Ariyan, Julie Gardner, Jennifer McQuade, Michael Wong, Li Zhao
Treatment with combined immune checkpoint blockade (CICB) targeting CTLA-4 and PD-1 is associated with clinical benefit across tumor types, but a high rate of immune-related adverse events (irAE). Insights into biomarkers and mechanisms of response a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24dcf02e4ee91c54a0239c73fe7cba34
https://doi.org/10.21203/rs.3.rs-119925/v1
https://doi.org/10.21203/rs.3.rs-119925/v1
Autor:
Elias Jabbour, Francesco Turturro, Irina Fernandez Curbelo, Padmanee Sharma, Roland L. Bassett, James P. Allison, Luis M Vence, Issa F. Khouri, Alison M. Gulbis, Denái R. Milton
Publikováno v:
Clinical Cancer Research. 24:1011-1018
Purpose: Prevention or treatment of relapsed lymphoid malignancies after hematopoietic stem cell transplantation (HSCT) requires novel strategies. We hypothesized that antitumor–cell responses could be enhanced by the addition of lenalidomide to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98a9f7696a727f36b5d50c3e7c1c737
https://doi.org/10.1158/1078-0432.ccr-17-2777
https://doi.org/10.1158/1078-0432.ccr-17-2777
Autor:
Ashley Mahne, Javier Chaparro-Riggers, John C. Lin, Anirban Maitra, Irina Fernandez Curbelo, Maria Gisela Higa, Samantha L. Bucktrout, Jorge Augusto Borin Scutti, Shalini S. Yadav, Ignacio I. Wistuba, Jorge Blando, Tao Sai, Pascua Edward Derrick, Terrence Park, Padmanee Sharma, Smith Bevin Marie Brady, James P. Allison, Sumit K. Subudhi, Hao Zhao, Luis M Vence
Publikováno v:
Clin Cancer Res
Purpose: Determine the differential effect of a FcγR-binding, mIgG2a anti-GITR antibody in mouse tumor models, and characterize the tumor microenvironment for the frequency of GITR expression in T-cell subsets from seven different human solid tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58bf706eb3a91ed895ac086954bbb2ee
https://pubmed.ncbi.nlm.nih.gov/31358539
https://pubmed.ncbi.nlm.nih.gov/31358539
Autor:
Jeffrey J. Molldrem, Claudia Mauri, Hila Shaim, Rayne H. Rouce, Abdullah Alsuliman, Takuya Sekine, Muharrem Muftuoglu, Enli Liu, Anushruti Sarvaria, Richard E. Champlin, Ahmad Khoder, Irina Fernandez Curbelo, Simrit Parmar, Ian K. McNiece, Paolo A. Muraro, Stephan Mielke, Hugues de Lavallade, Amin M. Alousi, Eric Yvon, Nina Shah, Elizabeth J. Shpall, Claude Chew, Kate Stringaris, Katy Rezvani, Nichola Cooper
Publikováno v:
Blood. 124(13)
A subset of regulatory B cells (Bregs) in mice negatively regulate T-cell immune responses through the secretion of regulatory cytokines such as IL-10 and direct cell-cell contact and have been linked to experimental models of autoimmunity, inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79ee80a9767d991d609efd7137652f7
https://pubmed.ncbi.nlm.nih.gov/25258134
https://pubmed.ncbi.nlm.nih.gov/25258134
Autor:
Rang A Kim, Issa F. Khouri, Luis M Vence, Elias Jabbour, Irina Fernandez Curbelo, Padmanee Sharma, Roland L. Bassett, Francesco Turturro, Denái R. Milton, Alison M. Gulbis
Publikováno v:
Blood. 128:1164-1164
Background: Prevention or treatment of relapse after SCT for lymphoid malignancies requires novel strategies. Targeting immune checkpoints could result in lasting responses but only in few patients. Combination strategies with targeted agents, such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99aaa5fea19ba225831fd40210c8d343
https://doi.org/10.1182/blood.v128.22.1164.1164
https://doi.org/10.1182/blood.v128.22.1164.1164