Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Irina Erchova"'
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Autosomal Dominant Optic Atrophy (ADOA) is an ophthalmological condition associated primarily with mutations in the OPA1 gene. It has variable onset, sometimes juvenile, but in other patients, the disease does not manifest until adult middle age desp
Externí odkaz:
https://doaj.org/article/203203017dc04594a108fe48c313638e
Autor:
Debbie Tudor, Vedran Kajić, Sara Rey, Irina Erchova, Boris Považay, Bernd Hofer, Kate A Powell, David Marshall, Paul L Rosin, Wolfgang Drexler, James E Morgan
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93916 (2014)
Optical coherence tomography (OCT) has revolutionises the diagnosis of retinal disease based on the detection of microscopic rather than subcellular changes in retinal anatomy. However, currently the technique is limited to the detection of microscop
Externí odkaz:
https://doaj.org/article/c481fd0469244bdaab36793b7ec4c186
Autor:
Mukhit Kulmaganbetov, Ryan J. Bevan, Nantheera Anantrasirichai, Alin Achim, Irina Erchova, Nick White, Julie Albon, James E. Morgan
Publikováno v:
Electronics; Volume 11; Issue 4; Pages: 669
Optical coherence tomography (OCT) is an imaging technique based on interferometry of backscattered lights from materials and biological samples. For the quantitative evaluation of an OCT system, artificial optical samples or phantoms are commonly us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c5b5eea45360d59c76e6b7552ee64d
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Frontiers in Neurology
Frontiers in Neurology
Autosomal Dominant Optic Atrophy (ADOA) is an ophthalmological condition associated primarily with mutations in the OPA1 gene. It has variable onset, sometimes juvenile, but in other patients, the disease does not manifest until adult middle age desp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774b1a1d0a6e0c2f38a7c1443de15de3
https://www.frontiersin.org/articles/10.3389/fneur.2021.641259/full
https://www.frontiersin.org/articles/10.3389/fneur.2021.641259/full
Autor:
Marcela Votruba, Amanda Mui, Sharon Seto, James Edwards Morgan, Rebecca A. Thirgood, Mark Andrew Good, Peter A. Williams, Caroline T Waters, Irina Erchova, Ryan J. Bevan
Publikováno v:
Brain Communications
A healthy mitochondrial network is essential for the maintenance of neuronal synaptic integrity. Mitochondrial and metabolic dysfunction contributes to the pathogenesis of many neurodegenerative diseases including dementia. OPA1 is the master regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc552263d0f143bed89a7f4aae77d890
http://europepmc.org/articles/PMC7566495
http://europepmc.org/articles/PMC7566495
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose: Retinal ganglion cells (RGCs) are susceptible to mitochondrial deficits and also the major cell type affected in patients with mutations in the OPA1 gene in autosomal dominant optic atrophy (ADOA). Here, we characterized mitochondria in RGCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af19224dade995cc3a421bed22687e05
https://orca.cardiff.ac.uk/id/eprint/132869/1/Opa1-Deficiency-Leads-to-Diminished-Mitochondrial-Bioenergetics-With-Compensatory-Increased-Mitochondrial-Motility2020Investigative-ophthalmology--visual-science.pdf
https://orca.cardiff.ac.uk/id/eprint/132869/1/Opa1-Deficiency-Leads-to-Diminished-Mitochondrial-Bioenergetics-With-Compensatory-Increased-Mitochondrial-Motility2020Investigative-ophthalmology--visual-science.pdf
Publikováno v:
Eye. 31:199-205
We provide an overview of developments in the use OCT imaging for the detection of retinal\ud ganglion cell damage in vivo that avoid use of any exogenous ligands to label cells. The\ud method employs high resolution OCT using broad spectral light so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a551d3f8253fe66a5796dd230c3681c
https://doi.org/10.1038/eye.2016.290
https://doi.org/10.1038/eye.2016.290
Autor:
James Edwards Morgan, James Fergusson, Frank Sengpiel, Nick White, Irina Erchova, Alexandre R. Tumlinson, Wolfgang Drexler
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Low coherence laser interferometry has revolutionised quantitative biomedical imaging of optically transparent structures at cellular resolutions. We report the first optical recording of neuronal excitation at cellular resolution in the inner retina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ed5da441301cf39e0719e3c92a9d3d
https://doi.org/10.1038/s41598-018-19975-x
https://doi.org/10.1038/s41598-018-19975-x
Autor:
James Edwards Morgan, Alin Achim, James Fergusson, Esra Tunc Gormus, Nick White, Irina Erchova, Nantheera Anantrasirichai, Lindsay B. Nicholson, M. Bundy
Publikováno v:
SIU
The most common cause of blindness in the world by far is known to be the Glaucoma condition. The increase in the ratio of cup to the disc area and the thinning of retinal layers are the most common symptoms of Glaucoma. Functional and structural fea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71f692b776a7b0f3bb03c4531117630f
https://doi.org/10.1109/siu.2017.7960648
https://doi.org/10.1109/siu.2017.7960648
Autor:
Julie Albon, Lindsay B. Nicholson, Nantheera Anantrasirichai, Rachel Valerie North, James Edwards Morgan, Alin Achim, Irina Erchova, Katharine Eirlys Mortlock
Publikováno v:
Computerized Medical Imaging and Graphics. 38:526-539
This paper presents novel pre-processing image enhancement algorithms for retinal optical coherence tomography (OCT). These images contain a large amount of speckle causing them to be grainy and of very low contrast. To make these images valuable for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6381cedec68ac067d072eb8f6ce0f059
https://doi.org/10.1016/j.compmedimag.2014.06.012
https://doi.org/10.1016/j.compmedimag.2014.06.012