Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Irina Chupikova"'
Autor:
Yaa F. Abu, Salma Singh, Junyi Tao, Irina Chupikova, Praveen Singh, Jingjing Meng, Sabita Roy
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTThere has been a rapid increase in neonates born with a history of prenatal opioid exposure. How prenatal opioid exposure affects pain sensitivity in offspring is of interest, as this may perpetuate the opioid epidemic. While few studies have
Externí odkaz:
https://doaj.org/article/e6375a2ca15b42128978f745a78a2f6b
Autor:
Bridget Truitt, Greeshma Venigalla, Praveen Singh, Salma Singh, Junyi Tao, Irina Chupikova, Sabita Roy
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTThe ongoing opioid epidemic has left millions of people suffering from opioid use disorder due to the over-prescription of highly addictive substances. Chronic opioid exposure leads to dependence, where the absence of the drug results in nega
Externí odkaz:
https://doaj.org/article/f1ce31cfed52417a87e06c3d3a2de209
Autor:
Richa Jalodia, Udhghatri Kolli, Regina Gonzalez Braniff, Junyi Tao, Yaa Fosuah Abu, Irina Chupikova, Shamsudheen Moidunny, Sundaram Ramakrishnan, Sabita Roy
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The gut microbial ecosystem exhibits a complex bidirectional communication with the host and is one of the key contributing factors in determining mucosal immune homeostasis or an inflammatory state. Opioid use has been established to induce gut micr
Externí odkaz:
https://doaj.org/article/de1f4e51ffd64649abfaff75ada6c351
Autor:
Nillu, Ghosh, Kousik, Kesh, Praveen Kumar, Singh, Umakant, Sharma, Irina, Chupikova, Sundaram, Ramakrishnan, Sabita, Roy
Publikováno v:
British Journal of Pharmacology. 180:1582-1596
Opioids are the gold standard drug for pain management, however, their effect on gastric dysfunction is relatively understudied. Opioid users have a higher incidence of gastric pathology leading to increased hospitalization. Herein, we investigated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e62876b3915339d88d7366c388fc22c
https://doi.org/10.1111/bph.16025
https://doi.org/10.1111/bph.16025
Autor:
Richa Jalodia, Yaa Fosuah Abu, Mark Ryan Oppenheimer, Bridget Herlihy, Jingjing Meng, Irina Chupikova, Junyi Tao, Nillu Ghosh, Rajib Kumar Dutta, Udhghatri Kolli, Yan Yan, Eridania Valdes, Madhulika Sharma, Umakant Sharma, Shamsudheen Moidunny, Sabita Roy
Publikováno v:
J Neuroimmune Pharmacol
Opioid use disorder (OUD) is defined as the chronic use or misuse of prescribed or illicitly obtained opioids and is characterized by clinically significant impairment. The etiology of OUD is multifactorial as it is influenced by genetics, environmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c107149b61ff0df6b084c2864b4a6ea
https://doi.org/10.1007/s11481-021-10046-z
https://doi.org/10.1007/s11481-021-10046-z
Autor:
Irina Chupikova, Maria T. Abreu, Umakant Sharma, Sabita Roy, Richa Jalodia, Li Zhang, Jingjing Meng, Sundaram Ramakrishnan, Yuguang Ban, Irina Fernandez, Nivis Brito
Publikováno v:
Proceedings of the National Academy of Sciences. 116:13523-13532
Prolonged exposure to opioids results in analgesic tolerance, drug overdose, and death. The mechanism underlying morphine analgesic tolerance still remains unresolved. We show that morphine analgesic tolerance was significantly attenuated in germfree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae70abf307325827b34ca5ef8ae2021f
https://doi.org/10.1073/pnas.1901182116
https://doi.org/10.1073/pnas.1901182116
Autor:
Ying-Jie Peng, Vladislav V. Makarenko, Ganesh K. Kumar, Aaron P. Fox, Xiuli Zhang, Nanduri R. Prabhakar, Anna Gridina, Irina Chupikova
Publikováno v:
Respiratory Physiology & Neurobiology. 259:75-85
The role of cystathionine-γ-lyase (CSE) derived H2S in the hypoxic and anoxic responses of the carotid body (CB) were examined. Experiments were performed on Sprague-Dawley rats, wild type and CSE knockout mice on C57BL/6 J background. Hypoxia (pO2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98705326f46f9efdb7c4a0bd409d5951
https://doi.org/10.1016/j.resp.2018.08.001
https://doi.org/10.1016/j.resp.2018.08.001
Autor:
Aaron P. Fox, Ying-Jie Peng, Irina Chupikova, Jayasri Nanduri, Vladislav V. Makarenko, Ganesh K. Kumar, Anna Girdina, Xiuli Zhang, Nanduri R. Prabhakar
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae44944c27ccf230b0a1df973686f2e6
https://doi.org/10.1096/fasebj.2019.33.1_supplement.551.14
https://doi.org/10.1096/fasebj.2019.33.1_supplement.551.14
Autor:
Ying-Jie, Peng, Vladislav V, Makarenko, Anna, Gridina, Irina, Chupikova, Xiuli, Zhang, Ganesh K, Kumar, Aaron P, Fox, Nanduri R, Prabhakar
Publikováno v:
Respiratory physiologyneurobiology. 259
The role of cystathionine-γ-lyase (CSE) derived H(2)S in the hypoxic and anoxic responses of the carotid body (CB) were examined. Experiments were performed on Sprague-Dawley rats, wild type and CSE knockout mice on C57BL/6J background. Hypoxia (pO(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a9913afe7a2eddc80951b52722335ad
https://pubmed.ncbi.nlm.nih.gov/30086385
https://pubmed.ncbi.nlm.nih.gov/30086385
Autor:
Gene Kim, Nanduri R. Prabhakar, Ying-Jie Peng, Ganesh K. Kumar, Solomon H. Snyder, Xiuli Zhang, Irina Chupikova, Gregg L. Semenza, Chirag Vasavda, Jayasri Nanduri, David L. McCormick, Robert J. Thomas, Anna Gridina, Thomas E. Scammell
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(6)
Sleep apnea, which is the periodic cessation of breathing during sleep, is a major health problem affecting over 10 million people in the United States and is associated with several sequelae, including hypertension and stroke. Clinical studies sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6f8d1625f5ce0b84a9fdb04a565b27
https://pubmed.ncbi.nlm.nih.gov/28115703
https://pubmed.ncbi.nlm.nih.gov/28115703