Výsledky vyhledávání - "Irina Baburina"

Point of care assay for blood aripiprazole concentrations: development, validation and utility

Autor: Matthew Atkins, David Taylor, Ana Catalan, Neville Desouza, Edward Chesney, Thomas J. Reilly, Irina Baburina, Mary Rose Hilaire, Luiz Dratcu, Robert Harland, Salvatore J. Salamone, Philip McGuire

Publikováno v: The British Journal of Psychiatry. :1-5

Background The antipsychotic aripiprazole is often used in the treatment of first-episode psychosis. Measuring aripiprazole blood levels provides an objective measure of treatment adherence, but this currently involves taking a venous blood sample an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a3bf9bf67909d246f4b449eb3ed9d79f
https://doi.org/10.1192/bjp.2023.58

Zobrazit plný text záznamu

Evaluation of a Nanoparticle-Based Busulfan Immunoassay for Rapid Analysis on Routine Clinical Analyzers

Autor: Regina V. Gill, Salvatore J. Salamone, Jodi Blake Courtney, JoAnn Gardiner, Leslie M. Shaw, Mary Rose Hilaire, Qing H. Meng, Irina Baburina, Michael C. Milone

Publikováno v: Therapeutic Drug Monitoring

Supplemental Digital Content is Available in the Text.
Background: Busulfan is an alkylating agent used in allogeneic hematopoietic stem cell transplantation for various malignant and nonmalignant disorders. Therapeutic drug monitoring of busulf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6e1edb093c13362fdfd64181aee53e
https://doi.org/10.1097/ftd.0000000000000883

Zobrazit plný text záznamu

Point-of-care measurement of clozapine concentration using a finger-stick blood sample

Autor: Matthew Atkins, Salvatore J. Salamone, Philip McGuire, Irina Baburina, Robert G. Harland, James H. MacCabe, David Taylor

Publikováno v: Journal of Psychopharmacology. 35:279-283

Background: The use of clozapine demands regular monitoring of clozapine plasma concentrations and of white blood cell parameters. The delay between sending blood samples for analysis and receiving the results hinders clinical care. Point-of-care tes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18524a2190b870092c863fd28ad6982
https://doi.org/10.1177/0269881121991567

Zobrazit plný text záznamu

Validation of a Commercial Assay and Decision Support Tool for Routine Paclitaxel Therapeutic Drug Monitoring (TDM)

Autor: Stefanie Kraff, Salvatore J. Salamone, Jodi Blake Courtney, Irina Baburina, Ralf A. Hilger, Daniel J. Cline, Ulrich Jaehde, Sonali P. Jog, Michael Craig Miller, Markus Joerger

Publikováno v: Therapeutic Drug Monitoring. 39:617-624

Background The value of therapeutic drug monitoring (TDM) for paclitaxel (PTX) was recently demonstrated in the largest TDM trial ever conducted in oncology. The trial demonstrated significant reduction in neuropathy when using TDM. Dose adjustment f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca74b615cc7590eb0b739968ea76e4d0
https://doi.org/10.1097/ftd.0000000000000446

Zobrazit plný text záznamu

A rapid homogeneous immunoassay to quantify gemcitabine in plasma for therapeutic drug monitoring (TDM)

Autor: Julianne L. Holleran, Richard J. Honeywell, Jodi Blake Courtney, Matt W. Ross, Daniel Kozo, Godefridus J. Peters, Irina Baburina, Salvatore J. Salamone, Jan H. Beumer, Michael Barrett, Rebecca L. Harney, Justin Jarrah

Publikováno v: Therapeutic Drug Monitoring, 39(3), 235-242. Lippincott Williams and Wilkins
Kozo, D, Ross, M W, Jarrah, J, Barrett, M, Harney, R L, Courtney, J B, Baburina, I, Holleran, J L, Beumer, J H, Peters, G J, Honeywell, R J & Salamone, S J 2017, ' Rapid homogeneous immunoassay to quantify gemcitabine in plasma for therapeutic drug monitoring ', Therapeutic Drug Monitoring, vol. 39, no. 3, pp. 235-242 . https://doi.org/10.1097/FTD.0000000000000402

Background: Gemcitabine (20,20-difluoro-20-deoxycytidine) is a nucleoside analog used as a single agent and in combination regimens for the treatment of a variety of solid tumors. Several studies have shown a relationship between gemcitabine peak pla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59817b33207b228d7cc503cb7e60edf2
https://europepmc.org/articles/PMC5460533/

Zobrazit plný text záznamu

Development and Evaluation of a Nanoparticle-Based Immunoassay for Determining Paclitaxel Concentrations on Routine Clinical Analyzers

Autor: Justin Jarrah, Rebecca L. Harney, Hadia K. Riaz, Salvatore J. Salamone, Hongxia Zhang, Daniel J. Cline, Gregory D. Lundell, Jodi Blake Courtney, Yunying Li, Irina Baburina, Makoto Miyazaki

Publikováno v: Therapeutic Drug Monitoring. 35:809-815

Paclitaxel (PTX; Taxol, Abraxane) is used in many regimens for breast cancer, non-small cell lung cancer (NSCLC), and ovarian cancer. Multiple studies have demonstrated that PTX exhibits a greater than 10-fold interpatient variability of clearance ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf909c0b6543a6c5585d596a21d48a9
https://doi.org/10.1097/ftd.0b013e318296be01

Zobrazit plný text záznamu

Engineering of recombinant antibody fragments to methamphetamine by anchored periplasmic expression

Autor: George Georgiou, Raymond A. Hui, Barrett R. Harvey, Brent L. Iverson, Armen B. Shanafelt, Steve Vitone, Irina Baburina

Publikováno v: Journal of Immunological Methods. 308:43-52

The detection of methamphetamine and other chemically related illicit drugs relies extensively on immunoassays. Here we report the cloning and affinity maturation of an anti-methamphetamine antibody which is being employed in the current commercial a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aec1846c18ca635e245aa9abfac18cd
https://doi.org/10.1016/j.jim.2005.09.017

Zobrazit plný text záznamu

P4‐048: BIOMARKER STABILITY IN CSF: PRE‐ANALYTICAL FACTORS IN A PROSPECTIVE COLLECTION

Autor: Daniel Kozo, Holly Soares, Adam J. Simon, Gary Feiss, Jodi Blake Courtney, Kim Williams, Caitlin N. Baldasano, George Green, Salvatore J. Salamone, Irina Baburina

Publikováno v: Alzheimer's & Dementia. 10

of the optical densities in ten repetitions of the standard curves was 5% for all standards. In the clinical part, at the cut off value 691 pg/mL, Ab 1-42 showed the sensitivity and the specificity of 69.3 %, and 88.9%, respectively, whereas at the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::13b3e29bd38935b09896c9aaf56965c3
https://doi.org/10.1016/j.jalz.2014.05.1562

Zobrazit plný text záznamu

Cellular Responses to Excess Phospholipid

Autor: Suzanne Jackowski, Irina Baburina

Publikováno v: Journal of Biological Chemistry. 274:9400-9408

Phosphatidylcholine (PtdCho) is the major membrane phospholipid in mammalian cells, and its synthesis is controlled by the activity of CDP:phosphocholine cytidylyltransferase (CCT). Enforced CCT expression accelerated the rate of PtdCho synthesis. Ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270e77f4d88db9c7c8c529e7b72e4922
https://doi.org/10.1074/jbc.274.14.9400

Zobrazit plný text záznamu

Regulation of thiamin diphosphate-dependent 2-oxo acid decarboxylases by substrate and thiamin diphosphate.Mg(II) – evidence for tertiary and quaternary interactions

Autor: John R. Guest, Yuhong Gao, Natalia S. Nemeria, Frank Jordan, Fusheng Guo, Ara Kahyaoglu, William Furey, Haijuan Li, Jizu Yi, Irina Baburina, Jue Wang

Publikováno v: Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1385:287-306

The regulatory mechanism of substrate activation in yeast pyruvate decarboxylase is triggered by the interaction of pyruvic acid with C221 located on the beta domain at20 A from the thiamin diphosphate (ThDP). To trace the putative information transf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077e3c1ff24d560298db94a837bfe3f6
https://doi.org/10.1016/s0167-4838(98)00075-2

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání