Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Irina Alimov"'
Autor:
Xinming Cai, Zinger Yang, John S. Reece-Hoyes, Edmund Harrington, John Alford, Tim Schuhmann, Luis Llamas, Rob Maher, Alicia Lindeman, Stephen M. Canham, Irina Alimov, Nadire Cochran, Carsten Russ, Suchithra Menon, Gregory R. Hoffman, Qiong Wang, John Concannon
Publikováno v:
Journal of Biological Chemistry. 294:3359-3366
Bile acids are critical metabolites in the gastrointestinal tract and contribute to maintaining intestinal immune homeostasis through cross-talk with the gut microbiota. The conversion of bile acids by the gut microbiome is now recognized as a factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276c48c6e9a8f74f5d3be2581e7eed33
https://doi.org/10.1074/jbc.ra118.005103
https://doi.org/10.1074/jbc.ra118.005103
Autor:
Amin Kamel, Elizabeth George, Xiaolin Gao, Antonin V. Tutter, Diksha Bhatia, Vic E. Myer, Mark Labow, Irina Alimov, Panagiotis Hatsis, Alan Buckler, Louis Wang, Mithat Gunduz, Christine D. Wilson, Earl Mcdonald, Gregory A. Michaud, Yucheng Ni, Kavitha Venkatesan, Jeffrey A. Porter, Yan Feng, Shaowen Wang, Deborah Rothman, Timothy Rasmusson, Mary Ellen Digan, David Farley, John A. Tallarico, Fred Harbinski
Publikováno v:
Chemistry & Biology. 22:1228-1237
SummaryIn an attempt to identify novel therapeutics and mechanisms to differentially kill tumor cells using phenotypic screening, we identified N-benzyl indole carbinols (N-BICs), synthetic analogs of the natural product indole-3-carbinol (I3C). To u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f299b5d21cce111f5872a6c80b374946
https://doi.org/10.1016/j.chembiol.2015.06.025
https://doi.org/10.1016/j.chembiol.2015.06.025
Publikováno v:
Cell Cycle. 5:1662-1668
HDAC inhibitors are promising antitumor drugs with several HDAC inhibitors already in clinical trials. LAQ824, a potent pan-HDAC inhibitor, has been shown to induce cell cycle arrest and cell death. However, the mechanism of its antitumor effects and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cde004b223bff20e9fb967a7f38cb19
https://doi.org/10.4161/cc.5.15.3099
https://doi.org/10.4161/cc.5.15.3099
Autor:
Herren Wu, Irina Alimov, Edward P. Nikonowicz, K. Uma, Iwona K. Wower, Peining Dong, Lihong Jiang, Robert A. Zimmermann, Denis Drygin
The assembly and structural integrity of the ribosome are guaranteed by specific interactions among its component proteins and RNAs. In Escherichia coli and other bacteria, many of the proteins that associate with rRNA also regulate the translation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45b30f267e82afabb538b8b9d93f71a8
https://doi.org/10.1128/9781555818142.ch10
https://doi.org/10.1128/9781555818142.ch10
Autor:
Ilango Balakrishnan, Etienne Danis, Angela Pierce, Krishna Madhavan, Dong Wang, Nathan Dahl, Bridget Sanford, Diane K. Birks, Nate Davidson, Dennis S. Metselaar, Michaël Hananja Meel, Rakeb Lemma, Andrew Donson, Trinka Vijmasi, Hiroaki Katagi, Ismail Sola, Susan Fosmire, Irina Alimova, Jenna Steiner, Ahmed Gilani, Esther Hulleman, Natalie J. Serkova, Rintaro Hashizume, Cynthia Hawkins, Angel M. Carcaboso, Nalin Gupta, Michelle Monje, Nada Jabado, Kenneth Jones, Nicholas Foreman, Adam Green, Rajeev Vibhakar, Sujatha Venkataraman
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108286- (2020)
Summary: Diffuse intrinsic pontine glioma (DIPG) is an incurable brain tumor of childhood characterized by histone mutations at lysine 27, which results in epigenomic dysregulation. There has been a failure to develop effective treatment for this tum
Externí odkaz:
https://doaj.org/article/df550ba18a7344fb83017de0c06084bc
Autor:
Sujatha Venkataraman, Irina Alimova, Rong Fan, Peter Harris, Nicholas Foreman, Rajeev Vibhakar
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10748 (2010)
MicroRNAs (miRNAs) are a class of short non-coding RNAs that regulate cell homeostasis by inhibiting translation or degrading mRNA of target genes, and thereby can act as tumor suppressor genes or oncogenes. The role of microRNAs in medulloblastoma h
Externí odkaz:
https://doaj.org/article/62eb636d546742efbe13770eea06cc7f