Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Irina, Utkina"'
Autor:
Irina Utkina-Sosunova, Alessia Chiorazzi, Mariangels de Planell-Saguer, Hai Li, Cristina Meregalli, Eleonora Pozzi, Valentina Alda Carozzi, Annalisa Canta, Laura Monza, Paola Alberti, Giulia Fumagalli, Charles Karan, Yalda Moayedi, Serge Przedborski, Guido Cavaletti, Francesco Lotti
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Peripheral neurotoxicity is a dose-limiting adverse reaction of primary frontline chemotherapeutic agents, including vincristine. Neuropathy can be so disabling that patients drop out of potentially curative therapy, negatively impacting can
Externí odkaz:
https://doaj.org/article/becfb928778f4455b47dda2d76d7e062
Akademický článek
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Autor:
Julian Agin‐Liebes, Richard A. Hickman, Jean Paul Vonsattel, Phyllis L. Faust, Xena Flowers, Irina Utkina Sosunova, Joel Ntiri, Richard Mayeux, Matthew Surface, Karen Marder, Stanley Fahn, Serge Przedborski, Roy N. Alcalay
Publikováno v:
Movement Disorders.
Autor:
John Parkinson, Paul D. W. Eckford, Irina Utkina, Michelle Di Paola, Onofrio Laselva, Tarini N.A. Gunawardena, Christine E. Bear, Leigh Wellhauser, Amy P. Wong, Sunny Xia, Zoe Ngan, Jia Xin Jiang, Felix Ratjen, Zoltán Bozóky, Theo J. Moraes
Publikováno v:
Stem Cell Reports
Summary For those people with cystic fibrosis carrying rare CFTR mutations not responding to currently available therapies, there is an unmet need for relevant tissue models for therapy development. Here, we describe a new testing platform that emplo
Autor:
Eduardo J, Pérez-Torres, Irina, Utkina-Sosunova, Vartika, Mishra, Peter, Barbuti, Mariangels, De Planell-Saguer, Georgia, Dermentzaki, Heather, Geiger, Anna O, Basile, Nicolas, Robine, Delphine, Fagegaltier, Kristin A, Politi, Paola, Rinchetti, Vernice, Jackson-Lewis, Matthew, Harms, Hemali, Phatnani, Francesco, Lotti, Serge, Przedborski
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(26)
Retromer is a heteropentameric complex that plays a specialized role in endosomal protein sorting and trafficking. Here, we report a reduction in the retromer proteins—vacuolar protein sorting 35 (VPS35), VPS26A, and VPS29—in patients with amyotr
Publikováno v:
Ecology. 103
Specific leaf area (SLA; one-sided leaf area per unit of dry mass) is a key trait indicating plant growth strategy and its responses to changing environments. Despite its high relevance for ecological research and recent efforts to mobilize the trait
Autor:
Sergey A Sosunov, Xavier Ameer, Zoya V Niatsetskaya, Irina Utkina-Sosunova, Veniamin I Ratner, Vadim S Ten
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120456 (2015)
This study demonstrates that in mice subjected to hypoxia-ischemia (HI) brain injury isoflurane anesthesia initiated upon reperfusion limits a release of mitochondrial oxidative radicals by inhibiting a recovery of complex-I dependent mitochondrial r
Externí odkaz:
https://doaj.org/article/432e7a840dae49aea3ffffb6dae864ae
Autor:
Konstantin Severinov, Yuri I. Wolf, Kira S. Makarova, Sergey Shmakov, Irina Utkina, Eugene V. Koonin
Publikováno v:
CRISPR J
CRISPR-Cas systems typically consist of a CRISPR array and cas genes that are organized in one or more operons. However, a substantial fraction of CRISPR arrays are not adjacent to cas genes. Definitive identification of such isolated CRISPR arrays r
Publikováno v:
Mathematical Optimization Theory and Operations Research ISBN: 9783030586560
In this paper we propose an efficient heuristic for the Vehicle Routing Problem on Trees (TVRP). An initial solution is constructed with a greedy algorithm based on the Depth-First Search (DFS) approach. To optimize initial solutions obtained by our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98e0d07b582d3d3680eb5461cb822be5
https://doi.org/10.1007/978-3-030-58657-7_30
https://doi.org/10.1007/978-3-030-58657-7_30
Publikováno v:
International Journal of Production Research. 56:3262-3273
The cell formation problem (CFP) is an NP-hard optimization problem considered for cell manufacturing systems. Because of its high computational complexity several heuristics have been developed for solving this problem. In this paper we present a br