Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Irida Papapostolou"'
Autor:
Konstantinos Lafazanis, Elias Begas, Irida Papapostolou, Hermis Iatrou, Nikos Sakellaridis, Dimitrios Vlassopoulos, Konstantinos Dimas
Publikováno v:
Medicina, Vol 60, Iss 6, p 864 (2024)
Background and Objectives: Gemcitabine has been used to treat various solid cancers, including, since 1997, metastatic pancreatic cancer. Here, we developed an HPLC-UV method to determine serum gemcitabine levels and use it in pharmacokinetic studies
Externí odkaz:
https://doaj.org/article/e1a1890c426145a5afcaabbffb9984d8
Publikováno v:
Methods and Protocols, Vol 6, Iss 5, p 94 (2023)
Although 2D in vitro cancer cell cultures have been used for decades as a first line-of-research tool to investigate antitumoral drugs and treatments, their use presents many drawbacks, including the poor resemblance of such cultures to the character
Externí odkaz:
https://doaj.org/article/fe220a9224e64d7497afd99404574948
Autor:
Barbara Preti, Jean-Sébastien Rougier, Irida Papapostolou, Florian Bochen, Christian E. Gerber, Hugues Abriel, Martin Lochner, Christine Peinelt
Publikováno v:
CHIMIA, Vol 76, Iss 12 (2022)
The transient receptor potential melastatin 4 (TRPM4) ion channel is ubiquitously expressed. Dysregulation and/or functional mutations of TRPM4 lead to several diseases. Within our studies, we screened for TRPM4 inhibitors and identified small molecu
Externí odkaz:
https://doaj.org/article/344d922443754d068dbe864dca6661ba
Autor:
Irida Papapostolou, Daniela Ross-Kaschitza, Florian Bochen, Christine Peinelt, Maria Constanza Maldifassi
Publikováno v:
Cells, Vol 12, Iss 15, p 2000 (2023)
Nicotine in tobacco is known to induce tumor-promoting effects and cause chemotherapy resistance through the activation of nicotinic acetylcholine receptors (nAChRs). Many studies have associated the α5 nicotinic receptor subunit (α5), and a specif
Externí odkaz:
https://doaj.org/article/a830cd96edcf4a45922be0ddd5dca604
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 890 (2023)
Despite recent therapeutic advances, pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive malignancies, with remarkable resistance to treatment, poor prognosis, and poor clinical outcome. More efficient therapeutic approaches ar
Externí odkaz:
https://doaj.org/article/d6fe1f7509724941b75593b9264ef0f5
Publikováno v:
Molecules, Vol 26, Iss 1, p 86 (2020)
Cancer is the second leading cause of death globally with an estimated 9.6 million deaths in 2018 and a sustained rise in its incidence in both developing and developed countries. According to the WHO, about 1 in 6 deaths is due to cancer. Despite th
Externí odkaz:
https://doaj.org/article/ec202827c20a477293bca83d0be1d67e
Publikováno v:
Molecules, Vol 26, Iss 86, p 86 (2021)
Cancer is the second leading cause of death globally with an estimated 9.6 million deaths in 2018 and a sustained rise in its incidence in both developing and developed countries. According to the WHO, about 1 in 6 deaths is due to cancer. Despite th